PfSPZ Vaccine induces focused humoral immune response in HIV positive and negative Tanzanian adultsResearch in context

Autor: Anneth Tumbo, Freia-Raphaella Lorenz, Annie S.P. Yang, Stephanie Sefried, Tobias Schindler, Maximilian Mpina, Jean-Pierre Dangy, Florence A. Milando, Mohammed A. Rashid, Gloria Nyaulingo, Kamaka Ramadhani, Said Jongo, Philip L. Felgner, Yonas Abebe, B. Kim Lee Sim, L.W. Preston Church, Thomas L. Richie, Peter F. Billingsley, Tooba Murshedkar, Stephen L. Hoffman, Salim Abdulla, Peter G. Kremsner, Benjamin Mordmüller, Claudia Daubenberger, Rolf Fendel

Publikováno v: EBioMedicine, Vol 108, Iss , Pp 105364- (2024)

Summary: Background: PfSPZ Vaccine, a promising pre-erythrocytic stage malaria vaccine candidate based on whole, radiation-attenuated Plasmodium falciparum (Pf) sporozoites (SPZ), has proven safe and effective in mediating sterile protection from mal

Externí odkaz: https://doaj.org/article/608a577a935848f082781131f68893d7

Wettability and Hardness Investigation of Nickel-Coated Precipitated Calcium Carbonate Sn-9Zn Composite Solder

Autor: L.W. Keong, F.F. Zainal, M.Z. Kasmuin, A.A. Mohamad, M.F.M. Nazari, M. Nabiałek, B. Jeż

Publikováno v: Archives of Metallurgy and Materials, Vol vol. 68, Iss No 3, Pp 1035-1040 (2023)

To fabricate a lead-free solder with better properties, a surface-modified precipitate calcium carbonate (PCC) was added as a reinforcement phase to tin-zinc (Sn-9Zn) solder. The surface modification of PCC was done by using electroless plating to de

Externí odkaz: https://doaj.org/article/ea31b54b11be4ea08b04431c11b5fb57

Synergetic deformation mechanisms in an Mg-Zn-Y-Zr alloy with intragranular LPSO structures

Autor: Z.Z. Peng, X.H. Shao, Z.M. Liang, D.L. Wang, L.W. Wang, X.L. Ma

Publikováno v: Journal of Magnesium and Alloys, Vol 11, Iss 5, Pp 1754-1768 (2023)

Deformation kink is one of the important strengthening mechanisms of the long-period-stacking-ordered (LPSO) phase containing magnesium (Mg) alloys, while the deformation twin is generally suppressed. To optimize the mechanical properties of LPSO con

Externí odkaz: https://doaj.org/article/1f327dce48e3408d9a21d5b6ed2ce41f

Sporozoite immunization: Innovative Translational Science to Support the Fight against malaria

Autor: Thomas L. Richie, L.W. Preston Church, Tooba Murshedkar, Peter F. Billingsley, Eric R. James, Mei-Chun Chen, Yonas Abebe, Natasha KC, Sumana Chakravarty, David Dolberg, Sara A. Healy, Halimatou Diawara, Mahamadou S. Sissoko, Issaka Sagara, David M. Cook, Judith E. Epstein, Benjamin Mordmüller, Melissa Kapulu, Andrea Kreidenweiss, Blandine Franke-Fayard, Selidji T. Agnandji, María-Silvia A. López Mikue, Matthew B.B. McCall, Laura Steinhardt, Martina Oneko, Ally Olotu, Ashley M. Vaughan, James G. Kublin, Sean C. Murphy, Said Jongo, Marcel Tanner, Sodiomon B. Sirima, Matthew B. Laurens, Claudia Daubenberger, Joana C. Silva, Kirsten E. Lyke, Chris J. Janse, Meta Roestenberg, Robert W. Sauerwein, Salim Abdulla, Alassane Dicko, Stefan H. I. Kappe, B. Kim Lee Sim, Patrick E. Duffy, Peter G. Kremsner, Stephen L. Hoffman

Publikováno v: Expert Review of Vaccines, Vol 0, Iss 0 (2023)

Introduction Malaria, a devastating febrile illness caused by protozoan parasites, sickened 247,000,000 people in 2021 and killed 619,000, mostly children and pregnant women in sub-Saharan Africa. A highly effective vaccine is urgently needed, especi

Externí odkaz: https://doaj.org/article/64ccc130995e4fbda0570808ef7ca47d

SARS-CoV-2 vaccine-induced antibodies protect against Omicron breakthrough infection

Autor: Eva A.M. Baerends, Astrid K. Hvidt, Joanne Reekie, Ole S. Søgaard, Nina B. Stærke, Dorthe Raben, Henrik Nielsen, Kristine T. Petersen, Maria R. Juhl, Isik S. Johansen, Susan O. Lindvig, Lone W. Madsen, Lothar Wiese, Lene S. Knudsen, Mette B. Iversen, Thomas Benfield, Kasper K. Iversen, Sidsel D. Andersen, Anna K. Juhl, Lisa L. Dietz, Signe R. Andreasen, Thea K. Fischer, Christian Erikstrup, Palle Valentiner-Branth, Jens Lundgren, Lars Østergaard, Martin Tolstrup, J. Lundgren, L. Østergaard, T. Benfield, L. Krohn-Dehli, D.K. Petersen, K. Fogh, E. Højmark, K.K. Iversen, P. Bek, V. Klastrup, F. Larsen, S.H. Rasmussen, M.H. Schleimann, S. Schieber, N.B. Stærke, A. Søndergaard, B. Tarp, M. Tousgaard, Y. Yehdego, J. Bodilsen, H. Nielsen, K.T. Petersen, M. Ruwald, R.K. Thisted, S.F. Caspersen, M. Iversen, L.S. Knudsen, J.L. Meyerhoff, L.G. Sander, L. Wiese, C. Abildgaard, I.K. Holden, N.E. Johansen, I.S. Johansen, L. Larsen, S.O. Lindvig, L.W. Madsen, A. Øvrehus, N.A. Kruse, H. Lomholdt, T.G. Krause, P. Valentiner-Branth, B. Søborg, T.K. Fischer, C. Erikstrup, S.R. Ostrowski, M. Tolstrup, O.S. Søgaard, D. Raben, E. Jylling, D. Hougaard, S.D. Andersen, K. Lykkegaard, S.R. Andreasen, E. Baerends, L.L. Dietz, A.K. Hvidt, A.K. Juhl, R. Olesen, K.K. Andersen, W. Bannister, C. Bjernved, T.W. Elsing, F.V. Esmann, M.A. Ghafari, E. Gravholdt, S.F. Jakobsen, M.L. Jakobsen, C.M. Jensen, T.Ø. Jensen, D. Kristensen, L.R. Kumar, C. Matthews, N. Normand, C. Olsson, J. Reekie, A. Traytel, T. Weide, A.M. Hvas, H. Støvring

Publikováno v: iScience, Vol 26, Iss 9, Pp 107621- (2023)

Summary: SARS-CoV-2 Omicron quickly spread globally, also in regions with high vaccination coverage, emphasizing the importance of exploring the immunological requirements for protection against Omicron breakthrough infection.The test-negative matche

Externí odkaz: https://doaj.org/article/ea485062804846ef9b467b59eb882465