Zobrazeno 1 - 10
of 52
pro vyhledávání: '"L.R. Hughes"'
Publikováno v:
Advances in Enzyme Regulation. 31:13-27
Heterocyclic para-aminobenzoate modifications of 2-desamino-2-methyl-5,8-dideazafolic acid and a series of its N10-substituted analogs have produced a number of interesting compounds that have enabled a deeper understanding of the biochemical events
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6c67404ca23a96fab07a73ba123b3a
https://doi.org/10.1016/0065-2571(91)90006-8
https://doi.org/10.1016/0065-2571(91)90006-8
Publikováno v:
MTT-S International Microwave Symposium Digest.
The paper describes a modified Von Hippel technique for determination of complex dielectric and magnetic properties of materials. The technique uses least square fit to derive the scatter matrix parameters for calibrating out internal reflection betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0da01b9ff701c097f6c2bfcdf7bdcfc8
https://doi.org/10.1109/mwsym.1977.1124380
https://doi.org/10.1109/mwsym.1977.1124380
Autor:
T. C. Stephens, M. Brown, Ann L. Jackman, F. T. Boyle, L.R. Hughes, Z. S. Matusiak, R. Kimbell, A. M. Slater, M N Smith
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461362876
ICI D1694, a quinazolinone based inhibitor of thymidylate synthase (TS) was developed to act in part through efficient metabolism to polyglutamates by the enzyme folypolyglutamyl synthetase (FPGS)1. The addition of γ-glutamates to agents such as ICI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1948c93ec204efe2efa9f8af416aa294
https://doi.org/10.1007/978-1-4615-2960-6_119
https://doi.org/10.1007/978-1-4615-2960-6_119
Autor:
K. Balmanno, P.R. Marsham, J. A. M. Bishop, A.L. Jackman, G.A. Taylor, L.R. Hughes, A.H. Calvert
Publikováno v:
Zurich, Switzerland, September 3–8, 1989
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72511e72a345a4b166fb652c989dd409
https://doi.org/10.1515/9783110889000-207
https://doi.org/10.1515/9783110889000-207
Autor:
L.R. Hughes, D. I. Jodrell, J. A. M. Bishop, A.L. Jackman, David Richard Newell, A.H. Calvert, G.A. Taylor
Publikováno v:
Zurich, Switzerland, September 3–8, 1989
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e88bebb738f13d2242e9b3d3125423ef
https://doi.org/10.1515/9783110889000-195
https://doi.org/10.1515/9783110889000-195
Autor:
Ah Calvert, L.R. Hughes, Kenneth R. Harrap, David Richard Newell, G.A. Taylor, Ann L. Jackman
Publikováno v:
Advances in Enzyme Regulation. 29:161-179
N10-Propargyl-5,8-dideazafolic acid (CB3717) has proved to be an interesting recent addition to the spectrum of antifolate drugs. Its sole biochemical locus of action appears to be thymidylate synthase, an inhibitory effect which is potentiated by in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44fd540127edba95a78f19f2c19f6c2
https://doi.org/10.1016/0065-2571(89)90099-x
https://doi.org/10.1016/0065-2571(89)90099-x
Autor:
Ralph A. Raphael, L.R. Hughes
Publikováno v:
Tetrahedron Letters. 17:1543-1546
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20ffda2121dee108346a717f04d4c84b
https://doi.org/10.1016/s0040-4039(00)71306-2
https://doi.org/10.1016/s0040-4039(00)71306-2
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781468456783
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::418edde9f060d6e82a309af8b930f222
https://doi.org/10.1007/978-1-4684-5676-9_56
https://doi.org/10.1007/978-1-4684-5676-9_56
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