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pro vyhledávání: '"L.K. Leung"'
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Akademický článek
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Publikováno v:
Journal of Thrombosis and Haemostasis. 20:238-244
BACKGROUND Kallikrein is generated when the contact system is activated, subsequently cleaving high molecular weight kininogen to bradykinin (BK). BK binds to bradykinin receptor 2, causing vascular leakage. BK is inactivated by proteolysis by the pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387d06ef683c50b2b3035152168e8e39
https://doi.org/10.1111/jth.15551
https://doi.org/10.1111/jth.15551
Autor:
Sameera Peraramelli, Qi Zhou, Qin Zhou, Bettina Wanko, Lei Zhao, Toshihiko Nishimura, Thomas H. Leung, Seiya Mizuno, Mamoru Ito, Timothy Myles, Thomas M. Stulnig, John Morser, Lawrence L.K. Leung
Publikováno v:
J Thromb Haemost
BACKGROUND: Osteopontin (OPN) is a multifunctional proinflammatory matricellular protein overexpressed in multiple human cancers and associated with tumor progression and metastases. Thrombin cleavage of OPN reveals a cryptic binding site for α(4)β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a42cba05d55c5e1170a617db3b9660
https://pubmed.ncbi.nlm.nih.gov/35108449
https://pubmed.ncbi.nlm.nih.gov/35108449
Autor:
Winnie W.Y. Tso, Ko Ling Chan, Tatia M.C. Lee, Nirmala Rao, S.L. Lee, Fan Jiang, Sophelia H.S. Chan, Wilfred H.S. Wong, Rosa S. Wong, Keith T.S. Tung, Jason C. Yam, Anthony P.Y. Liu, Gilbert T. Chua, Jaime S. Rosa Duque, Almen L.N. Lam, K.M. Yip, L.K. Leung, Yuliang Wang, Jin Sun, Guanghai Wang, Godfrey C.F. Chan, Ian C.K. Wong, Patrick Ip
Publikováno v:
Child Abuse & Neglect
Background Children with special educational needs (SEN) are more vulnerable during the COVID-19 pandemic with risk of poor mental wellbeing and child maltreatment. Objective To examine the impact of COVID-19 on the mental health of children with SEN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e23bc34b97155dcdf69415dcb5e2eba
https://doi.org/10.1016/j.chiabu.2021.105457
https://doi.org/10.1016/j.chiabu.2021.105457
Autor:
John Morser, Dempsey Garrett, Qin Zhou, Fredric B. Kraemer, Yiqiang Zhang, Wen-Jun Shen, Dachuan Dong, Pinglin Yang, Xiao Hao, Andreas Stahl, Lei Zhao, Lawrence L.K. Leung, Shuo Qiu
Publikováno v:
FASEB J
Apart from its role in inflammation and immunity, chemerin is also involved in white adipocyte biology. To study the role of chemerin in adipocyte metabolism, we examined the function of chemerin in brown adipose tissue. Brown and white adipocyte pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada140604be8eae1e4d9249a44368bb7
https://doi.org/10.1096/fj.202100156r
https://doi.org/10.1096/fj.202100156r
Autor:
John Morser, William H. Robinson, Xiaomei Ge, Lei Zhao, Yasuto Yamaguchi, Lawrence L.K. Leung
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-9 (2018)
Arthritis Research & Therapy
Arthritis Research & Therapy
Background Chemerin is a chemoattractant involved in immunity that also functions as an adipokine. Chemerin is secreted as an inactive precursor (chem163S), and its activation requires proteolytic cleavages at its C-terminus, involving proteases in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a2774abf442cde23b4273f860a452b
http://link.springer.com/article/10.1186/s13075-018-1615-y
http://link.springer.com/article/10.1186/s13075-018-1615-y
Autor:
Yasuto Yamaguchi, Xiaomei Ge, Caroline Berube, John Morser, Loredana Bury, Paolo Gresele, Lei Zhao, Lawrence L.K. Leung
Publikováno v:
Blood. 131:353-364
Chemerin is a chemoattractant and adipokine that circulates in blood as inactive prochemerin (chem163S). Chem163S is activated by a series of C-terminal proteolytic cleavages resulting in diverse chemerin forms with different levels of activity. We s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9982ff3efbc7d08c896fba9f492c5fe5
https://doi.org/10.1182/blood-2017-07-792580
https://doi.org/10.1182/blood-2017-07-792580
Autor:
William H. Robinson, Jayme C.B. Koltsov, Grace Xiong, Lawrence L.K. Leung, Nidhi Bhutani, Nithya Lingampalli, Constance R. Chu
Publikováno v:
Am J Sports Med
Background: Autologous platelet-rich plasma (PRP) is widely used for a variety of clinical applications. However, clinical outcome studies have not consistently shown positive effects. The composition of PRP differs based on many factors. An improved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80ac3dff7124453a12fe0d1714943af5
https://doi.org/10.1177/0363546517740845
https://doi.org/10.1177/0363546517740845
Akademický článek
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