Zobrazeno 1 - 10
of 26
pro vyhledávání: '"L.J.M. Cross"'
Autor:
Madeleine Ennis, K.D. Buchanan, Liam G Heaney, L.J.M. Cross, Christopher Shaw, Lorcan McGarvey
Publikováno v:
Thorax. 53:357-362
BACKGROUND—Multiple sensory neuropeptides are present in human airways and may contribute to diseases such as asthma. This study quantified and characterised substance P (SP), neurokinin A (NKA), and calcitonin gene related peptide (CGRP) immunorea
Publikováno v:
Clinical & Experimental Allergy. 28:196-204
Background Metachromatic cells obtained from asthmatic subjects demonstrate increased spontaneous and stimulated histamine release in vitro. Their ability to synthesize and store proinflammatory cytokines has focused renewed interest on their role in
Publikováno v:
Inflammation Research. 46:306-309
Objective and Design: This study examined whether bradykinin and neurokinin A activate human pulmonary mast cells retrieved by bronchoalveolar lavage (BAL).¶Subjects: BAL samples were obtained at routine bronchoscopy from 14 unpreselected patients.
Autor:
L.J.M. Cross, Michael A. Matthay, Cecilia O'Kane, Cliona McDowell, Daniel F. McAuley, Jospeh J. Elborn
Publikováno v:
Cross, L J M, O'Kane, C M, McDowell, C, Elborn, J J, Matthay, M A & McAuley, D F 2013, ' Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction – a randomised placebo-controlled trial (KARE): study protocol ', Trials, vol. 14, 51 . https://doi.org/10.1186/1745-6215-14-51
Cross, LJM; O'Kane, CM; McDowell, C; Elborn, JJ; Matthay, MA; & McAuley, DF. (2013). Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction-a randomised placebo-controlled trial (KARE): Study protocol. Trials, 14(1). doi: 10.1186/1745-6215-14-51. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/36n4t3ht
Cross, Laurence JM; O’Kane, Cecilia M; McDowell, Cliona; Elborn, Jospeh J; Matthay, Michael A; & McAuley, Daniel F. (2013). Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction ¿ a randomised placebo-controlled trial (KARE): study protocol. Trials, 14(1), 51. doi: http://dx.doi.org/10.1186/1745-6215-14-51. Retrieved from: http://www.escholarship.org/uc/item/9kj677vf
Cross, LJM; O'Kane, CM; McDowell, C; Elborn, JJ; Matthay, MA; & McAuley, DF. (2013). Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction-a randomised placebo-controlled trial (KARE): Study protocol. Trials, 14(1). doi: 10.1186/1745-6215-14-51. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/36n4t3ht
Cross, Laurence JM; O’Kane, Cecilia M; McDowell, Cliona; Elborn, Jospeh J; Matthay, Michael A; & McAuley, Daniel F. (2013). Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction ¿ a randomised placebo-controlled trial (KARE): study protocol. Trials, 14(1), 51. doi: http://dx.doi.org/10.1186/1745-6215-14-51. Retrieved from: http://www.escholarship.org/uc/item/9kj677vf
Background Acute lung injury is a common, devastating clinical syndrome associated with substantial mortality and morbidity with currently no proven therapeutic interventional strategy to improve patient outcomes. The objectives of this study are to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5362aed1e27c7b7e013112a9d0d31d5
https://pure.qub.ac.uk/en/publications/3f429d9b-257f-499c-880d-5874c95935f9
https://pure.qub.ac.uk/en/publications/3f429d9b-257f-499c-880d-5874c95935f9
Autor:
L.J.M. Cross, Madeleine Ennis, Michael Bienert, Wolfram Gaida, E. Krause, Annette G. Beck-Sickinger, Günther Jung
Publikováno v:
British journal of pharmacology, 117(2): 325-332
1. Neuropeptide-induced histamine release is thought to occur via receptor-independent mechanisms, with net charge and lipophilicity being important factors. 2. In this study, the histamine releasing ability of neuropeptide Y (NPY), two C-terminal se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::521048aac5a0e871364bb9930045bccf
https://repository.publisso.de/resource/frl:6405176
https://repository.publisso.de/resource/frl:6405176
Autor:
Margitta Dathe, Amanda L. Salmon, Christopher Shaw, L.J.M. Cross, Sven Rothemund, Michael Beyermann, Lars Thim, Alexandra E. Irvine, Michael Bienert, Gerd Krause, Paul Canning, T. R. J. Lappin
Publikováno v:
The Journal of biological chemistry. 276(13)
On the basis of histamine release from rat peritoneal mast cells, an octadecapeptide was isolated from the skin extract of the Northern Leopard frog (Rana pipiens). This peptide was purified to homogeneity using reversed-phase high performance liquid
Autor:
Madeleine Ennis, Michael Beyermann, Margitta Dathe, Michael Bienert, Eberhard Krause, G. Krause, Dorothea Lorenz, L.J.M. Cross
Publikováno v:
European journal of pharmacology. 291(3)
Mast cell activation by polycationic substances is believed to result from a direct activation of G protein α subunits and it was suggested that the adaption of amphipathic, α-helical conformations wouuld allow the peptide to reach the cytosolic co
Publikováno v:
Agents and actions.
Substance P (SP) stimulates human skin and rodent mast cells. Since neuropeptide-mediated reflexes may be important in asthma, the ability of SP to stimulate human mast cells obtained at bronchoalveolar lavage (BAL) was examined. Routine BAL (n = 22)
Publikováno v:
Inflammation Research. 45:S11-S12
Autor:
Eberhard Krause, L.J.M. Cross, M. Beyerman, Michael Bienert, Madeleine Ennis, Annette G. Beck-Sickinger
Publikováno v:
Biochemical Society Transactions. 22:7S-7S