The decrease in uroporphyrinogen decarboxylase activity induced by ethanol predisposes rats to the development of porphyria and accelerates xenobiotic-triggered porphyria, regardless of hepatic damage

Autor: M.C. Ríos de Molina, M.B. Mazzetti, M. Galigniana, C. Aldonatti, J.M. Tomio, L.C. San Martín de Viale

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 35, Iss 11, Pp 1273-1283 (2002)

We evaluated the porphyrinogenic ability of ethanol (20% in drinking water) per se, its effect on the development of sporadic porphyria cutanea tarda induced by hexachlorobenzene in female Wistar rats (170-190 g, N = 8/group), and the relationship wi

Externí odkaz: https://doaj.org/article/e039bd81d5d44e6c8c2d477d5545f302

Differential effects of paraquat on oxidative stress parameters and polyamine levels in two freshwater invertebrates

Autor: L.C. San Martín de Viale, N. R. Verrengia Guerrero, A.B. Della Penna, Gisela Kristoff, Adriana C. Cochón, María Natalia Piol

Publikováno v: Ecotoxicology and Environmental Safety. 68:286-292

Paraquat is still a widely used herbicide in several countries. Its toxic action on plants occurs through a one-electron reduction interfering with the photosynthesis process. By a similar reaction, the herbicide may induce peroxidation processes in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d5e65424446e6ada8b4c1d698effa5
https://doi.org/10.1016/j.ecoenv.2006.11.010

The decrease in uroporphyrinogen decarboxylase activity induced by ethanol predisposes rats to the development of porphyria and accelerates xenobiotic-triggered porphyria, regardless of hepatic damage

Autor: L.C. San Martín de Viale, M.B. Mazzetti, J.M. Tomio, M. C. Rios De Molina, C. Aldonatti, M. Galigniana

Publikováno v: Brazilian Journal of Medical and Biological Research v.35 n.11 2002
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
Brazilian Journal of Medical and Biological Research, Volume: 35, Issue: 11, Pages: 1273-1283, Published: NOV 2002
Brazilian Journal of Medical and Biological Research, Vol 35, Iss 11, Pp 1273-1283 (2002)

We evaluated the porphyrinogenic ability of ethanol (20% in drinking water) per se, its effect on the development of sporadic porphyria cutanea tarda induced by hexachlorobenzene in female Wistar rats (170-190 g, N = 8/group), and the relationship wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b67c7f668ba9cf0e50b7b9e9b2971c8
https://doi.org/10.1590/s0100-879x2002001100004

Heme metabolism after discontinued hexachlorobenzene administration in rats: possible irreversible changes and biomarker for hexachlorobenzene persistence

Autor: Carmen Aldonatti, S.C Billi de Catabbi, L.C. San Martín de Viale

Publikováno v: Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology. 127:165-175

The aim of the present study was to determine whether short-term administration of hexachlorobenzene (HCB) (1 g/kg body wt., suspended in water, 5 days/week), could cause and maintain marked porphyria in the absence of the exogenous drug, and whether

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8b40dd76ebdec262c5e9b48a359aeb
https://doi.org/10.1016/s0742-8413(00)00149-3

Studies on the active centre(s) of rat liver porphyrinogen carboxy-lyase. in vivo effect of hexachlorobenzene on decarboxylation site(s) of porphyrinogens

Autor: L.C. San Martín de Viale, S.C Billi de Catabbi

Publikováno v: International Journal of Biochemistry. 26:595-600

1. 1. The role of histidine on the decarboxylation of porphyrinogens of 7-, 6-, and 5-COOH III brought about by porphyrinogen carboxy-lyase (PCL) was studied. 2. 2. For this purpose hepatic PCL from normal and hexachlorobenzene (HCB) treated rats wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d936a76726910ae171e196a5e64b5b1
https://doi.org/10.1016/0020-711x(94)90019-1