Výsledky vyhledávání - "L.A.Th. Hilgers"

Oral immunisation of naive and primed animals with transgenic potato tubers expressing LT-B

Autor: D Bosch, D.E.A Florack, W.J.A Boersma, T.J van der Wal, L.A.Th Hilgers, J.W Molthoff, Tosca G.M. Lauterslager, Jan P. M. Langeveld

Publikováno v: Vaccine, 19, 2749-2755
Vaccine 19 (2001)

The efficacy of edible vaccines produced in potato tubers was examined in mice. Transgenic plants were developed by Agrobacterium tumefaciens-mediated transformation. The antigen selected was the non-toxic B subunit of the Escherichia coli enterotoxi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5245d1f29cf35552d8ce5a122a7434
https://doi.org/10.1016/s0264-410x(00)00513-2

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Sulfolipo-cyclodextrin in squalane-in-water as a novel and safe vaccine adjuvant

Autor: B. Boon, L.A.Th Hilgers, M. Fochesato, I. Nicolas, G. Lejeune

Publikováno v: Vaccine 17 (1999) 3
Vaccine, 17(3), 219-228

Previously, we described synergistic adjuvanticity of combinations of synthetic sulfolipo(SL)-derivatives of polysaccharide (SL-polysaccharides) and squalane-in-water emulsions (squalane/W). In this paper, effects of type of polysaccharide and nature

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d0892d4b695146e21b1e0f69590488d
https://doi.org/10.1016/s0264-410x(98)00195-9

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A novel non-mineral oil-based adjuvant. II. Efficacy of a synthetic sulfolipopolysaccharide in a squalane-in-water emulsion in pigs

Autor: Marinus Wijnand Weststrate, T. Dazelle, A. Luitjens, B. Groenveld, L.A.Th Hilgers, P. L. I. Platenburg

Publikováno v: Vaccine. 12:661-665

The adjuvanticity of a sulfolipopolysaccharide (SLP) incorporated into a squalane-in-water emulsion (SLP/S/W) was compared with that of a mineral oil-in-water (O/W) adjuvant currently used in commercial porcine vaccines. Groups of pigs were immunized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51cdfb3e44cfe0060d86caaab88b68f9
https://doi.org/10.1016/0264-410x(94)90273-9

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Adjuvant effects of sulfolipo-cyclodextrin in a squalane-in-water and water-in-mineral oil emulsions for BHV-1 vaccines in cattle

Autor: A.M. Sadir, M.J. Dus Santos, Patricia Ines Zamorano, Sonia Alejandra Romera, L.A.Th Hilgers, M. Puntel, M.V. Borca, J. Blanco Viera, V.L Alcon

Publikováno v: Vaccine. 19(1)

The antibody and cell mediated immune responses induced by BHV-1 were analysed in cattle after vaccination and challenge exposure to the virulent strain LA of BHV-1. Animals were vaccinated intramuscularly (IM) with inactivated virus vaccines against

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b10a29fdb936c34c949f2527123491f2
https://pubmed.ncbi.nlm.nih.gov/10924795

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Alkyl-esters of polyacrylic acid as vaccine adjuvants

Autor: B. Boon, M. Strebelle, G. Lejeune, L.A.Th Hilgers, I. Nicolas, E. Dewil

Publikováno v: Vaccine 16 (1998)
Vaccine, 16, 1575-1581

Previously, we demonstrated that polyacrylic acid (PAA) augmented significantly the immune response to inactivated Newcastle disease virus (iNDV) in chickens, but that efficacy was insufficient to replace the water-in-mineral oil (W/O) adjuvant appli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec541812ea39a2fbb49d779a9d43f54f
https://research.wur.nl/en/publications/alkyl-esters-of-polyacrylic-acid-as-vaccine-adjuvants

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Quantitative analysis of a synthetic adjuvant by an immunoassay

Autor: M. Fochesato, I. Nicolas, B. Boon, G. Lejeune, L.A.Th Hilgers

Publikováno v: Journal of Immunological Methods 218 (1998)
Journal of Immunological Methods, 218, 105-116

Antibodies against a sulpholipo-derivative of synthetic polysucrose (SL-Ficoll) were prepared with the purpose of developing a detection system for this adjuvant component. SL-Ficolls with polysucrose backbones of 400 kDa (SL-Ficoll400) or 22 kDa (SL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea8abbe6bf369653b42590e9dc44588
https://research.wur.nl/en/publications/quantitative-analysis-of-a-synthetic-adjuvant-by-an-immunoassay

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Effect of various adjuvants on secondary immune response in chickens

Autor: B. Boon, E Dewil, L.A.Th Hilgers, G. Lejeune, I. Nicolas

Publikováno v: Veterinary Immunology and Immunopathology 66 (1998)
Veterinary Immunology and Immunopathology, 66, 159-171

Stimulatory effects of several types of adjuvants on secondary antibody response to inactivated Newcastle disease virus (iNDV) were examined in chickens. For this purpose, animals were primed with iNDV without adjuvant resulting in a low but signific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbca3eafd6e0e4bf86aacb64eaca7b07
https://research.wur.nl/en/publications/effect-of-various-adjuvants-on-secondary-immune-response-in-chick

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Detection of Marek's disease virus antigen in chickens by a novel immunoassay

Autor: L.A.Th. Hilgers, S.H.M. Jeurissen, Marinus Wijnand Weststrate, Rudolf Scholten

Publikováno v: Journal of virological methods. 27(2)

An immunoassay was developed to detect Marek's disease virus (MDV) antigen on the tips of feathers obtained from MDV-infected chickens. MDV in follicular debris on the feather tip was demonstrated by use of a specific monoclonal antibody. The princip

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9fc6501886bf2c8bb1f4c658333b991
https://pubmed.ncbi.nlm.nih.gov/2156882

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