Orexin A injection into the ventral medial prefrontal cortex induces antidepressant-like effects: Possible involvement of local Orexin-1 and Trk receptors

Autor: Samia R. L. Joca, Ariandra G. Sartim, L.A. Stanquini

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Rationale Reduced levels of orexin-A (OXA) in the central nervous system (CNS) have been associated with the pathophysiology of depression and its exogenous administration promotes antidepressant-like effect. The mechanisms associated with these effe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::902be7a9a9cee301b0589ad585c8e6d9
https://pubmed.ncbi.nlm.nih.gov/32827568

Repeated treatment with nitric oxide synthase inhibitor attenuates learned helplessness development in rats and increases hippocampal BDNF expression

Autor: Francisco Silveira Guimarães, Caroline Biojone, L.A. Stanquini, Sâmia R.L. Joca

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Stanquini, L A, Biojone, C, Guimarães, F S & Joca, S R 2018, ' Repeated treatment with nitric oxide synthase inhibitor attenuates learned helplessness development in rats and increases hippocampal BDNF expression ' Acta Neuropsychiatrica, vol. 30, no. 3, pp. 127-136 . https://doi.org/10.1017/neu.2017.28

BackgroundNitric oxide synthase (NOS) inhibitors induce antidepressant-like effects in animal models sensitive to acute drug treatment such as the forced swimming test. However, it is not yet clear if repeated treatment with these drugs is required t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54bbf826880a6ebc2ee5d73b8fd4ba5d

Purinergic signaling is involved in the stress response and antidepressant effect

Autor: M.A. Pinto e Silva, Sâmia R.L. Joca, Caroline Biojone, Darcy Ribeiro, Plinio C. Casarotto, L.A. Stanquini, Gregers Wegener

Publikováno v: European Neuropsychopharmacology. 26:S263

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb7392199e99159853589b35b8006a9f
https://doi.org/10.1016/s0924-977x(16)31142-7

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