Predictors and associations of the persistent airflow limitation phenotype in asthma: a post-hoc analysis of the ATLANTIS study

Autor: Tessa M Kole, Elise Vanden Berghe, Monica Kraft, Judith M Vonk, Martijn C Nawijn, Salman Siddiqui, Kai Sun, Leonardo M Fabbri, Klaus F Rabe, Kian Fan Chung, Gabriele Nicolini, Alberto Papi, Chris Brightling, Dave Singh, Thys van der Molen, Sven-Erik Dahlén, Alvar Agusti, Rosa Faner, Jadwiga A Wedzicha, Gavin C Donaldson, Ian M Adcock, Lies Lahousse, Huib A M Kerstjens, Maarten van den Berge, P. Badorrek, M. Broeders, W.G. Boersma, A. Chetta, A. Cukier, M. D'Amato, R. Djukanovic, M.P. Foschino, C. Gessner, N. Hanania, R. Martin, S. Milleri, R. Olivenstein, P. Paggiaro, E. Pizzichini, V. Plaza Moral, D.S. Postma, N. Scichilone, R. Schilz, A. Spanevello, R. Stelmach, J.S. Vroegop, O.S. Usmani, Q. Zhang, H. Ahmed, D. Allen, S. Ballereau, M.K. Batuwitage, A. Bedding, A.F. Behndig, A. Berglind, A. Berton, J. Bigler, M.J. Boedigheimer, K. Bønnelykke, P. Brinkman, A. Bush, D. Campagna, C. Casaulta, A. Chaiboonchoe, T. Davison, B. De Meulder, I. Delin, P. Dennison, P. Dodson, L. El Hadjam, D. Erzen, C. Faulenbach, K. Fichtner, N. Fitch, E. Formaggio, M. Gahlemann, G. Galffy, D. Garissi, T. Garret, E. Guillmant-Farry, E. Henriksson, U. Hoda, J.M. Hohlfeld, X. Hu, A. James, K. Johnson, N. Jullian, G. Kerry, M. Klüglich, R. Knowles, J.R. Konradsen, K. Kretsos, L. Krueger, A-S. Lantz, C. Larminie, P. Latzin, D. Lefaudeux, N. Lemonnier, L.A. Lowe, R. Lutter, A. Manta, A. Mazein, L. McEvoy, A. Menzies-Gow, N. Mores, C.S. Murray, K. Nething, U. Nihlén, R. Niven, B. Nordlund, S. Nsubuga, J. Pellet, C. Pison, G. Praticò, M. Puig Valls, K. Riemann, J.P. Rocha, C. Rossios, G. Santini, M. Sagi, S. Scott, N. Sehgal, A. Selby, P. Söderman, A. Sogbesan, F. Spycher, S. Stephan, J. Stokholm, M. Sunther, M. Szentkereszty, L. Tamasi, K. Tariq, S Valente, W.M. Van Aalderen, C.M. Van Drunen, J. Van Eyll, A. Vyas, W. Yu, W. Zetterguist, Z. Zolkipli, A.H. Zwinderman, A. Agusti, J.A. Wedzicha, G.C. Donaldson, R. Faner, R. Breyer-Kohansal, A.H. Maitland-van der Zee, E. Melén, J.P. Allinson, L.E.G.W. Vanfleteren, J. Vestbo, I.M. Adcock, L. Lahousse, M. Van den Berge, P. Alter, F. Barbe, C.E. Brightling, M.K. Breyer, O.C. Burghuber, M. Casas, K.F. Chung, B.G. Cosío, F. Crispi, J. De Batlle, J.W. Fitting, J. Garcia, J. Hallberg, S. Hartl, D. Jarvis, A. Mathioudakis, L. Nicod, A. Papi, A. Ritchie, T. Sigsgaard, P.J. Sterk, A. Ullman, K. Vellvé, C. Vogelmeier, A.M. Wheelock, C.E. Wheelock

Publikováno v: The Lancet Respiratory Medicine, 11(1), 55-64. Elsevier Limited
The Lancet. Respiratory Medicine, 11(1), 55-64. ELSEVIER SCI LTD
LANCET RESPIRATORY MEDICINE

BACKGROUND: Persistent airflow limitation (PAL) occurs in a subset of patients with asthma. Previous studies on PAL in asthma have included relatively small populations, mostly restricted to severe asthma, or have no included longitudinal data. The a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398c06c4dcd6d075885b6472a2c74e3f
http://hdl.handle.net/10044/1/98623

IL-17-high asthma with features of a psoriasis immunophenotype

Autor: Jörgen Östling, Marleen van Geest, James P.R. Schofield, Zala Jevnikar, Susan Wilson, Jonathan Ward, Rene Lutter, Dominick E. Shaw, Per S. Bakke, Massimo Caruso, Sven-Erik Dahlen, Stephen J. Fowler, Ildikó Horváth, Norbert Krug, Paolo Montuschi, Marek Sanak, Thomas Sandström, Kai Sun, Ioannis Pandis, Charles Auffray, Ana R. Sousa, Yike Guo, Ian M. Adcock, Peter Howarth, Kian Fan Chung, Jeanette Bigler, Peter J. Sterk, Paul J. Skipp, Ratko Djukanović, Outi Vaarala, I.M. Adcock, H. Ahmed, C. Auffray, P. Bakke, A.T. Bansal, F. Baribaud, S. Bates, E.H. Bel, J. Bigler, H. Bisgaard, M.J. Boedigheimer, K. Bønnelykke, J. Brandsma, P. Brinkman, E. Bucchioni, D. Burg, A. Bush, M. Caruso, A. Chaiboonchoe, P. Chanez, K.F. Chung, C.H. Compton, J. Corfield, A. D'Amico, S.E. Dahlen, B. De Meulder, R. Djukanovic, V.J. Erpenbeck, D. Erzen, K. Fichtner, N. Fitch, L.J. Fleming, E. Formaggio, S.J. Fowler, U. Frey, M. Gahlemann, T. Geiser, Y. Guo, S. Hashimoto, J. Haughney, G. Hedlin, P.W. Hekking, T. Higenbottam, J.M. Hohlfeld, C. Holweg, I. Horváth, P. Howarth, A.J. James, R. Knowles, A.J. Knox, N. Krug, D. Lefaudeux, M.J. Loza, R. Lutter, A. Manta, S. Masefield, A. Mazein, A. Meiser, R.J.M. Middelveld, M. Miralpeix, P. Montuschi, N. Mores, C.S. Murray, J. Musial, D. Myles, L. Pahus, I. Pandis, S. Pavlidis, P. Powell, G. Praticò, M. Puig N. Rao, J. Riley, A. Roberts, G. Roberts, A. Rowe, T. Sandström, W. Seibold, A. Selby, D.E. Shaw, R. Sigmund, F. Singer, P.J. Skipp, A.R. Sousa, P.J. Sterk, K. Sun, B. Thornton, W.M. van Aalderen, M. van Geest, J. Vestbo, N.H. Vissing, A.H. Wagener, S.S. Wagers, Z. Weiszhart, C.E. Wheelock, S.J. Wilson, Antonios Aliprantis, David Allen, Kjell Alving, P. Badorrek, David Balgoma, S. Ballereau, Clair Barber, Manohara Kanangana Batuwitage, A. Bautmans, A. Bedding, A.F. Behndig, Jorge Beleta, A. Berglind, A. Berton, Grazyna Bochenek, Armin Braun, D. Campagna, Leon Carayannopoulos, C. Casaulta, Romanas Chaleckis, B. Dahlén, imothy Davison, Jorge De Alba, Inge De Lepeleire, Tamara Dekker, Ingrid Delin, P. Dennison, Annemiek Dijkhuis, Paul Dodson, Aleksandra Draper, K. Dyson, Jessica Edwards, L. El Hadjam, Rosalia Emma, Magnus Ericsson, C. Faulenbach, Breda Flood, G. Galffy, Hector Gallart, D. Garissi, J. Gent, M. Gerhardsson de Verdier, D. Gibeon, Cristina Gomez, Kerry Gove, Neil Gozzard, E. Guillmant-Farry, E. Henriksson, Lorraine Hewitt, U. Hoda, Richard Hu, Sile Hu, X. Hu, E. Jeyasingham, K. Johnson, N. Jullian, Juliette Kamphuis, Erika J. Kennington, Dyson Kerry, G. Kerry, M. Klüglich, Hugo Knobel, Johan Kolmert, J.R. Konradsen, Maxim Kots, Kosmas Kretsos, L. Krueger, Scott Kuo, Maciej Kupczyk, Bart Lambrecht, A.-S. Lantz, Christopher Larminie, L.X. Larsson, P. Latzin, N. Lazarinis, N. Lemonnier, Saeeda Lone-Latif, L.A. Lowe, Alexander Manta, Lisa Marouzet, Jane Martin, Caroline Mathon, L. McEvoy, Sally Meah, A. Menzies-Gow, Leanne Metcalf, Maria Mikus, Philip Monk, Shama Naz, K. Nething, Ben Nicholas, U. Nihlén, Peter Nilsson, R. Niven, B. Nordlund, S. Nsubuga, Antonio Pacino, Susanna Palkonen, J. Pellet, Giorgio Pennazza, Anne Petrén, Sandy Pink, C. Pison, Anthony Postle, Malayka Rahman-Amin, Lara Ravanetti, Emma Ray, Stacey Reinke, Leanne Reynolds, K. Riemann, Martine Robberechts, J.P. Rocha, C. Rossios, Kirsty Russell, Michael Rutgers, G. Santini, Marco Santoninco, M. Saqi, Corinna Schoelch, S. Scott, N. Sehgal, Marcus Sjödin, Barbara Smids, Caroline Smith, Jessica Smith, Katherine M. Smith, P. Söderman, A. Sogbessan, F. Spycher, Doroteya Staykova, S. Stephan, J. Stokholm, K. Strandberg, M. Sunther, M. Szentkereszty, L. Tamasi, K. Tariq, John-Olof Thörngren, Jonathan Thorsen, S. Valente, Marianne van de Pol, C.M. van Drunen, Jonathan Van Eyll, Jenny Versnel, Anton Vink, C. von Garnier, A. Vyas, Frans Wald, Samantha Walker, Kristiane Wetzel, Coen Wiegman, Siân Williams, Xian Yang, Elizabeth Yeyasingham, W. Yu Amgen, W. Zetterquist, Z. Zolkipli, A.H. Zwinderman

Publikováno v: Journal of Allergy and Clinical Immunology, 144(5), 1198-1213. Mosby Inc.
U-BIOPRED Study Group 2019, ' IL-17-high asthma with features of a psoriasis immunophenotype ', The Journal of allergy and clinical immunology . https://doi.org/10.1016/j.jaci.2019.03.027
Journal of allergy and clinical immunology, 144(5), 1198-1213. Mosby Inc.
Östling, J R, van Geest, M, U-BIOPRED Study Group, Schofield, J P R, Jevnikar, Z, Wilson, S, Ward, J, Lutter, R, Shaw, D E, Bakke, P S, Caruso, M, Dahlen, S-E, Fowler, S J, Horváth, I, Krug, N, Montuschi, P, Sanak, M, Sandström, T, Sun, K, Pandis, I, Auffray, C, Sousa, A R, Guo, Y, Adcock, I M, Howarth, P, Chung, K F, Bigler, J, Sterk, P J, Skipp, P J, Djukanović, R & Vaarala, O 2019, ' IL-17–high asthma with features of a psoriasis immunophenotype ', Journal of Allergy and Clinical Immunology, vol. 144, no. 5, pp. 1198-1213 . https://doi.org/10.1016/j.jaci.2019.03.027

Background The role of IL-17 immunity is well established in patients with inflammatory diseases, such as psoriasis and inflammatory bowel disease, but not in asthmatic patients, in whom further study is required. Objective We sought to undertake a d

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https://publica.fraunhofer.de/handle/publica/259279

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