Basic Science * 208. Stem Cell Factor Expression is Increased in the Skin of Patients with Systemic Sclerosis and Promotes Proliferation and Migration of Fibroblasts in vitro

Autor: S. Karrar, X. Shiwen, J. Nikotorowicz-Buniak, D. J. Abraham, C. Denton, R. Stratton, R. Bayley, K. A. Kite, E. Clay, J. P. Smith, G. D. Kitas, C. Buckley, S. P. Young, L. Ye, L. Zhang, J. Goodall, H. Gaston, H. Xu, P. M. Lutalo, Y. Zhao, L. Meng Choong, S. Sangle, J. Spencer, D. D'Cruz, O. J. Rysnik, K. McHugh, P. Bowness, L. Rump-Goodrich, D. Mattey, O. Kehoe, J. Middleton, A. Cartwright, C. Schmutz, A. Askari, D. H. Gardner, L. E. Jeffery, K. Raza, D. M. Sansom, M. Fitzpatrick, G. Wallace, S. Young, J. Shaw, H. Hatano, A. Cauli, J. L. Giles, A. Mathieu, S. Kollnberger, S. Webster, L. Ellis, L. M. O'Brien, T. J. Fitzmaurice, A. Nazeer Moideen, L. Evans, L. Osgood, A. Williams, S. Jones, C. Thomas, V. O'Donnell, M. Nowell, L. Ouboussad, S. Savic, L. J. Dickie, J. Hintze, C. H. Wong, G. P. Cook, M. Buch, P. Emery, M. F. McDermott, S. A. Hardcastle, C. L. Gregson, K. Deere, G. Davey Smith, P. Dieppe, J. H. Tobias, E. Dennison, M. Edwards, J. Bennett, D. Coggon, K. Palmer, C. Cooper, D. McWilliams, A. Young, P. D. Kiely, D. Walsh, H. J. Taylor, I. Harding, J. Hutchinson, I. Nelson, A. Blom, J. Tobias, E. Clark, J. Parker, M. Bukhari, K. Jayakumar, P. Kiely, J. Diffin, M. Lunt, T. Marshall, J. Chipping, D. Symmons, S. Verstappen, J. Bluett, J. Bowes, P. Ho, N. McHugh, D. Buden, O. Fitzgerald, A. Barton, J. R. Glossop, N. B. Nixon, R. D. Emes, P. T. Dawes, W. E. Farrell, D. L. Mattey, I. C. Scott, S. Steer, S. Seegobin, A. M. Hinks, S. Eyre, A. Morgan, A. G. Wilson, L. Hocking, P. Wordsworth, J. Worthington, A. Cope, C. M. Lewis, S. Guerra, B. A. Ahmed, D. Abraham, C. Fonseca, J. Robinson, J. Taylor, L. Haroon Rashid, E. Flynn, J. Isaacs, J. H. Barrett, B. Kingston, M. Ahmed, J. R. Kirwan, R. Marshall, K. Chapman, R. Pearson, C. Heycock, C. Kelly, M. Rynne, V. Saravanan, J. Hamilton, A. Saeed, R. Coughlan, J. J. Carey, Z. Farah, W. Matthews, C. Bell, S. Petford, L.-M. Tibbetts, K. M. J. Douglas, W. Holden, J. Ledingham, M. Fletcher, R. Winfield, Z. Price, K. Mackay, C. Dixon, R. Oppong, S. Jowett, E. Nicholls, D. Whitehurst, S. Hill, A. Hammond, E. Hay, K. Dziedzic, C. Righetti, M. Lebmeier, V. L. Manning, M. Hurley, D. L. Scott, E. Choy, L. Bearne, E. Nikiphorou, S. Morris, D. James, E. C. Wong, J. Long, A. Fletcher, S. Holmes, P. Hockey, M. Abbas, C. Chattopadhyay, J. Flint, M. Gayed, K. Schreiber, S. Arthanari, M. Nisar, M. Khamashta, C. Gordon, I. Giles, J. Robson, A. Kiran, J. Maskell, N. Arden, A. Hutchings, A. Emin, D. Culliford, B. Dasgupta, W. Hamilton, R. Luqmani, H. Jethwa, D. Rowczenio, H. Trojer, T. Russell, J. Loeffler, P. Hawkins, H. Lachmann, I. Verma, A. Syngle, P. Krishan, N. Garg, S. P. McGowan, D. T. Gerrard, H. Chinoy, W. E. Ollier, R. G. Cooper, J. A. Lamb, L. Taborda, P. Correia Azevedo, D. Isenberg, K. M. Leyland, A. Judge, D. Hunter, D. Hart, M. K. Javaid, M. H. Edwards, A. E. Litwic, K. A. Jameson, D. Deeg, J. Cushnaghan, A. Aihie Sayer, D. Jagannath, C. Parsons, L. Stoppiello, P. Mapp, S. Ashraf, D. Wilson, R. Hill, B. Scammell, C. Wenham, P. Shore, R. Hodgson, A. Grainger, J. Aaron, L. Hordon, P. Conaghan, Y. Bar-Ziv, Y. Beer, Y. Ran, S. Benedict, N. Halperin, M. Drexler, A. Mor, G. Segal, A. Lahad, A. Haim, U. Rath, D. M. Morgensteren, M. Salai, A. Elbaz, V. G. Vasishta, E. Derrett-Smith, R. Hoyles, K. Khan, A. Ezeonyeji, G. Takhar, V. Ong, L. Loughrey, L.-A. Bissell, E. Hensor, G. Abignano, A. Redmond, F. Del Galdo, F. C. Hall, A. Malaviya, S. Baker, A. Furlong, A. Mitchell, A. L. Godfrey, M. Ruddlesden, A. Hadjinicolaou, M. Hughes, T. Moore, N. O'Leary, A. Tracey, H. Ennis, G. Dinsdale, C. Roberts, A. Herrick, C. P. Denton, L. Guillevin, E. Hunsche, D. Rosenberg, B. Schwierin, M. Scott, T. Krieg, M. Anderson, M. Matucci-Cerinic, R. Alade, S. Xu, S. Nihtyanova, K. E. Clark, F. W. K. Tam, R. Unwin, R. J. Stratton, B. Schreiber, C. Seng Edwin Lim, E. Corsiero, N. Sutcliffe, H. Wardemann, C. Pitzalis, M. Bombardieri, H. Tahir, S. Donnelly, M. Greenwood, T. O. Smith, V. Easton, H. Bacon, E. Jerman, K. Armon, F. Poland, A. Macgregor, D. van der Heijde, J. Sieper, D. Elewaut, A. L. Pangan, D. Nguyen, C. Badenhorst, S. Kirby, D. White, A. Harrison, J. A. Garcia, S. Stebbings, J. W. MacKay, S. Aboelmagd, K. Gaffney, A. Deodhar, J. Braun, M. Mack, B. Hsu, T. Gathany, C. Han, R. D. Inman, N. Cooper-Moss, J. Packham, V. Strauss, J. E. Freeston, L. Coates, J. Nam, A. R. Moverley, P. Helliwell, R. Wakefield, P. Mease, R. Fleischmann, J. Wollenhaupt, D. Kielar, F. Woltering, C. Stach, B. Hoepken, T. Arledge, D. Gladman, G. Coteur, A. Kavanaugh, O. Purcaru, I. McInnes, A. B. Gottlieb, L. Puig, P. Rahman, C. Ritchlin, S. Li, Y. Wang, A. Mendelsohn, M. Doyle, W. Tillett, D. Jadon, G. Shaddick, C. Cavill, G. Robinson, R. Sengupta, E. Korendowych, C. de Vries, R. C. Thomas, T. Shuto, N. Busquets-Perez, H. Marzo-Ortega, D. McGonagle, G. Richards, S. Bingham, P. John Hamlin, R. Adshead, S. Cambridge, P. Suppiah, M. Cullinan, A. Nolan, W. M. Thompson, H. R. Mathieson, S. L. Mackie, D. Bryer, M. Krutikov, L. Gray, E. Bruce, A. Keat, W. Innes, R. Pandit, L. Kay, S. Lapshina, L. Myasoutova, S. Erdes, D. Wallis, N. Waldron, I. Thorne, C. Harris, K. Vohra, D. Khinchi, L. Kaur, A. Jones, N. Harrison, D. Harris, T. Jones, J. Rees, A. Bennett, S. Fazal, N. Tugnet, N. Barkham, N. Basu, A. McClean, L. Harper, E. N. Amft, N. Dhaun, R. A. Luqmani, M. A. Little, D. R. Jayne, O. Flossmann, J. McLaren, V. Kumar, D. M. Reid, G. J. Macfarlane, G. Jones, M. Yates, R. A. Watts, L. Igali, C. Mukhtyar, H. Doll, S. Yew, R. Suppiah, P. Hoglund, D. Jayne, K. Westman, W. Win Maw, P. Patil, M. Williams, T. Adizie, D. Christidis, F. Borg, A. Robertson, A. P. Croft, S. Smith, S. Carr, S. Youssouf, A. Salama, C. Pusey, M. Morgan

Publikováno v: Rheumatology. 52:i135-i172

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4274168dcb6af09e716060f4a62004f8
https://doi.org/10.1093/rheumatology/ket195

THU0182 Waste Not, Want Not: Is Anti-TNF Wastage Preventable?

Autor: S. Petford, C. Bell, Karen M J Douglas, L.-M. Tibbetts

Publikováno v: Annals of the Rheumatic Diseases. 72:A225.1-A225

Background Anti-TNF therapy (αTNF) has revolutionised rheumatology with undeniable improvements in patients’ care, but also made it an expensive speciality. Humira, Enbrel and Infliximab are independently within the top 10 selling pharmaceutical p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4cd32360977c0c1ae52d3e9ba412a90e
https://doi.org/10.1136/annrheumdis-2013-eular.710

In vivo selection of a highly metastatic cell line from a human pancreatic carcinoma in the nude mouse

Autor: M P, Vezeridis, G N, Tzanakakis, P A, Meitner, C M, Doremus, L M, Tibbetts, P, Calabresi

Publikováno v: Cancer. 69(8)

A cell line with high metastatic capacity to the liver was established by sequential passages of a human pancreatic cancer cell line through the nude mouse liver. A subline, L3.5, established after five passages of the fast-growing variant (FG) of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::da3ad77f4678a7ae469ae62ff0e47961
https://pubmed.ncbi.nlm.nih.gov/1544114

Cytotoxic liponucleotide analogs. II. Antitumor activity of CDP-diacylglycerol analogs containing the cytosine arabinoside moiety

Autor: J G, Turcotte, S P, Srivastava, J M, Steim, P, Calabresi, L M, Tibbetts, M Y, Chu

Publikováno v: Biochimica et biophysica acta. 619(3)

Among events limiting the effectiveness of cancer chemotherapy are the general lack of preferential uptake of anticancer drugs by tumor cells and the occurrence of drug resistance. An approach has been undertaken to explore whether or not such events

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5ba1edeec603404e68d6772bbbee0c1e
https://pubmed.ncbi.nlm.nih.gov/7459369

Chemotherapy of cell-line-derived human colon carcinomas in mice immunosuppressed with antithymocyte serum

Autor: L M, Tibbetts, M Y, Chu, J C, Hager, D L, Dexter, P, Calabresi

Publikováno v: Cancer. 40

An in vivo model is described for assessing the antitumor activity of chemotherapeutic agents. Tumors derived from human colon carcinoma cell lines injected into antithymocyte serum (ATS) immunosuppressed mice were used. In this system, both antitumo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::be982c788adf7da5cbfba37645263708
https://pubmed.ncbi.nlm.nih.gov/303540