Výsledky vyhledávání - "L. van Dussen"

Notch Pathway Regulation of Intestinal Cell Fate

Autor: Linda C. Samuelson, Peter J. Dempsey, Kelli L. Van Dussen

The Notch signaling pathway is a critical regulator of the intestinal epithelium, playing a fundamental role in stem cell maintenance, progenitor cell proliferation, and cell fate determination. Notch controls iterative functions in developing intest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d7343438223d496001d24ba44332ccc
https://doi.org/10.1016/b978-0-12-809954-4.00006-2

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Value of plasma chitotriosidase to assess non-neuronopathic Gaucher disease severity and progression in the era of enzyme replacement therapy

Autor: Johanna E. M. Groener, Johannes M. F. G. Aerts, Rolf G. Boot, L. van Dussen, Carla E. M. Hollak, E. J. Hendriks

Publikováno v: Journal of inherited metabolic disease, 37(6), 991-1001. Springer Netherlands

Gaucher disease (GD) is caused by deficiency of the enzyme glucocerebrosidase catalysing the regular lysosomal degradation of glucosylceramide. In the common non-neuropathic variant of GD, glucosylceramide-laden macrophages (Gaucher cells) accumulate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55cace68febb91464c2652485a256a5f
https://doi.org/10.1007/s10545-014-9711-x

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Akademický článek

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Taliglucerase alfa leads to favorable bone marrow responses in patients with type I Gaucher disease

Autor: Mario Maas, Raul Chertkoff, Hanna Rosenbaum, Johannes M. F. G. Aerts, Ari Zimran, Milan Petakov, Carla E. M. Hollak, Deborah Elstein, Einat Brill-Almon, David Aviezer, Erik M. Akkerman, L. van Dussen

Publikováno v: Blood cells, molecules & diseases, 50(3), 206-211. Academic Press Inc.

Taliglucerase alfa (Protalix Biotherapeutics, Israel) is a carrot-cell-expressed recombinant human beta-glucocerebrosidase recently approved in the United States for the treatment of type 1 Gaucher disease (GD). As bone disease is one of the most deb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86167d66aec94ebdaddd9f5d0d730e5e
https://doi.org/10.1016/j.bcmd.2012.11.001

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Akademický článek

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Heterogeneous pattern of bone disease in adult type 1 Gaucher disease: Clinical and pathological correlates

Autor: Carla E. M. Hollak, Paul Lips, H.W. van Essen, L. van Dussen, Nathalie Bravenboer

Publikováno v: Blood Cells Molecules and Diseases, 53(3), 118-123. Academic Press Inc.
van Dussen, L, Lips, P T A M, van Essen, H W, Hollak, C E M & Bravenboer, N 2014, ' Heterogeneous pattern of bone disease in adult type 1 Gaucher disease: Clinical and pathological correlates ', Blood Cells Molecules and Diseases, vol. 53, no. 3, pp. 118-123 . https://doi.org/10.1016/j.bcmd.2014.05.005
Blood cells, molecules & diseases, 53(3), 118-123. Academic Press Inc.

Gaucher disease (GD) is a lysosomal storage disorder characterized by accumulation of glucosylceramide in macrophages, so-called Gaucher cells, as a result of a deficiency of the lysosomal enzyme glucocerebrosidase. Bone complications are an importan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d56324bcbc0c6ef1a87141ea770299
https://research.vu.nl/en/publications/d02495cb-21c6-449e-8998-5ec9da7ac041

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Markers of bone turnover in Gaucher disease: modeling the evolution of bone disease

Autor: C. E. M. Hollak, Mario Maas, Johanna E. M. Groener, Johannes M. F. G. Aerts, V.E. Everts, J.A.K. Blokland, L. van Dussen, Ineke D. C. Jansen, Nathalie Bravenboer, Paul Lips

Publikováno v: Journal of clinical endocrinology and metabolism, 96(7), 2194-2205. The Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 96(7), 2194-2205. Oxford University Press
van Dussen, L, Lips, P T A M, Everts, V E, Bravenboer, N, Jansen, I D C, Groener, J E M, Maas, M, Blokland, J A K, Aerts, J M F G & Hollak, C E M 2011, ' Markers of Bone Turnover in Gaucher Disease: Modeling the Evolution of Bone Disease ', Journal of Clinical Endocrinology and Metabolism, vol. 96, no. 7, pp. 2194-2205 . https://doi.org/10.1210/jc.2011-0162
Journal of Clinical Endocrinology and Metabolism, 96(7), 2194-2205. The Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 96(7), 2194-2205
van Dussen, L, Lips, P, Everts, V E, Bravenboer, N, Jansen, I D C, Groener, J E M, Maas, M, Blokland, J A K, Aerts, J M F G & Hollak, C E M 2011, ' Markers of bone turnover in Gaucher disease: modeling the evolution of bone disease ', Journal of Clinical Endocrinology and Metabolism, vol. 96, no. 7, pp. 2194-2205 . https://doi.org/10.1210/jc.2011-0162

Context: Gaucher disease (GD) is a lysosomal storage disorder characterized by abundant presence of macrophages. Bone complications and low bone density are believed to arise from enhanced bone resorption mediated through macrophage-derived factors.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ab3814caa09db30f970fdd3aac37f3
https://pure.amc.nl/en/publications/markers-of-bone-turnover-in-gaucher-disease-modeling-the-evolution-of-bone-disease(3a4cfcca-a767-4dad-8cd9-35d226b18ad0).html

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