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pro vyhledávání: '"L. de Paz"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 137-144 (2019)
Here, we present an exploratory study on the fluorous-assisted synthesis of chondroitin sulfate (CS) oligosaccharides. Following this approach, a CS tetrasaccharide was prepared. However, in contrast to our previous results, a significant loss of β-
Externí odkaz:
https://doaj.org/article/555066e4307f4517a741806489eb09f4
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 496 (2022)
Chondroitin sulfate (CS) E is the natural ligand for pleiotrophin (PTN) in the central nervous system (CNS) of the embryo. Some structures of PTN in solution have been solved, but no precise location of the binding site has been reported yet. Using 1
Externí odkaz:
https://doaj.org/article/0b1cc7963ca84ebf86c360c7b8382750
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3026 (2022)
Pleiotrophin (PTN) is a neurotrophic factor that participates in the development of the embryonic central nervous system (CNS) and neural stem cell regulation by means of an interaction with sulfated glycosaminoglycans (GAGs). Chondroitin sulfate (CS
Externí odkaz:
https://doaj.org/article/1b7e90c2408b4d3fb09f956f1e5a68a8
Publikováno v:
Current Medicinal Chemistry. 29:1173-1192
Langerin is a C-type Lectin expressed at the surface of Langerhans cells, which play a pivotal role protecting organisms against pathogen infections. To address this aim, Langerin presents at least two recognition sites, one Ca2+-dependent and anothe
Publikováno v:
Molecules, Vol 24, Iss 8, p 1591 (2019)
Here, we report the synthesis of a sulfated, fully protected hexasaccharide as a glycosaminoglycan mimetic and the study of its interactions with different growth factors: midkine, basic fibroblast growth factor (FGF-2) and nerve growth factor (NGF).
Externí odkaz:
https://doaj.org/article/1d9004e8568b401da8987c78ea62b5c1
Publikováno v:
Pharmaceuticals; Volume 15; Issue 5; Pages: 496
Chondroitin sulfate (CS) E is the natural ligand for pleiotrophin (PTN) in the central nervous system (CNS) of the embryo. Some structures of PTN in solution have been solved, but no precise location of the binding site has been reported yet. Using 1
Autor:
José L. de Paz, Pedro M. Nieto
Publikováno v:
Methods in Molecular Biology ISBN: 9781071613979
The classic, solution-phase synthesis of glycosaminoglycan (GAG) oligosaccharides is hampered by the numerous, time-consuming chromatographic purifications required for the isolation of the glycosylation products after each coupling step between suga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2565eb66c4727eed6f39f4781d3517e
https://doi.org/10.1007/978-1-0716-1398-6_4
https://doi.org/10.1007/978-1-0716-1398-6_4
Autor:
José L, de Paz, Pedro M, Nieto
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2303
The classic, solution-phase synthesis of glycosaminoglycan (GAG) oligosaccharides is hampered by the numerous, time-consuming chromatographic purifications required for the isolation of the glycosylation products after each coupling step between suga
Autor:
Marcel L. De Paz
A thorough numerical analysis of micro-impingement cooling for application in high pressure turbine vanes is presented. The fundamental flow of an axisymmetric jet is first modeled and studied to ascertain the validity of the results. Subsequent, a f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a97d2e642681f2cbed1f5b818a0b48d5
https://doi.org/10.32920/ryerson.14665782
https://doi.org/10.32920/ryerson.14665782
Publikováno v:
Beilstein Journal of Organic Chemistry
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 137-144 (2019)
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 137-144 (2019)
Here, we present an exploratory study on the fluorous-assisted synthesis of chondroitin sulfate (CS) oligosaccharides. Following this approach, a CS tetrasaccharide was prepared. However, in contrast to our previous results, a significant loss of β-