Zobrazeno 1 - 10
of 26
pro vyhledávání: '"L. Z. Topol"'
Autor:
N. I. Solovyeva, V. F. Pozdnev, F. L. Kisseljov, T. A. Zakamaldina-Zama, Elvira A. Dilakyan, T. O. Balayevskaya, L. Z. Topol
Publikováno v:
International Journal of Cancer. 60:495-500
Aspartyl and cysteine proteinases at distinct stages of carcinogenesis were analyzed in rat embryo fibroblasts, sequentially immortalized and transformed by 2 different genes: the early region of simian adenovirus SA7 and c-Ha-ras oncogene. The dynam
Autor:
F. L. Kisseljov, Elvira A. Dilakyan, O.N Lubkova, T. A. Gureeva, L. Z. Topol, S. V. Vinokurova, N. I. Solovyeva, V. A. Zhurbitskaya
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 309(1)
Methods: The activities of cathepsin L and its endogenous inhibitors were analyzed in rat embryo fibroblasts, immortalized and transformed by different genes. Results: Regardless of the transfecting agent used (DNA of adenovirus SA7 or polyomavirus L
Cloning of the murine Drm gene (Cktsf1b1) and characterization of its oncogene suppressible promoter
Publikováno v:
Cytogenetics and cell genetics. 89(3-4)
The Drm gene, first identified in rat cells in our laboratory, appears to play a significant role in early embryo patterning and limb bud development. We have now isolated mouse Drm (mDrm) cDNA as well as genomic DNA clones and have mapped the Drm ge
Autor:
E A, Dilakian, S V, Vinokurova, V A, Zhurbitskaia, E V, Komissarova, L Z, Topol', F L, Kiselev, N I, Solov'eva
Publikováno v:
Voprosy meditsinskoi khimii. 44(1)
Expression of cysteine proteinases, cathepsins L and B, and their inhibitors was studied out in three model systems of rat embryo fibroblasts, sequentially immortalized and transformed by different genes. In Model I rat embryo fibroblasts were immort
Autor:
L Z, Topol, D G, Blair
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 6(9)
We have characterized activation of the MAP kinase cascade in an inducible system in response to the temperature-sensitive (ts) expression of the v-mos oncogene. Transformation of immortalized rat embryo fibroblasts by a ts isolate of Moloney murine
Publikováno v:
Voprosy meditsinskoi khimii. 40(3)
Study of the expression of the aspartyl cathepsin D-like and cysteine cathepsin L-like proteinases was carried out on a model system of rat embryo fibroblasts. The model system employed makes it possible to distinguish two discrete successive stages
Autor:
A. G. Tatosyan, T. A. Zakamaldina, L. Z. Topol, E. N. Uvarova, V. A. Matveeva, G. I. Deichman, T. E. Kluchareva
Publikováno v:
International journal of cancer. 51(6)
We have previously shown that RSV-SR-transformed hamster cells acquire high resistance to H2O2, i.e. the cytotoxic product of activated macrophages (H2OR2) and that they begin to secrete PGE (PGEs), thus inactivating the CTA of NK cells. Among normal
Autor:
E. A. Musatkina, L. Z. Topol, G. I. Deichman, M. S. Shtutman, A. G. Tatosyan, N. P. Kisseljova
Publikováno v:
Modern Trends in Human Leukemia IX ISBN: 9783540543602
Previously, different hamster cell lines transformed in vitro by Rous sarcoma virus (RSV) (SR-D strain) were established [1]. These cells displayed different levels of spontaneous metastatic activity in syngenic animals. The structure of RSV provirus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e72386edf73f31eb3d392996c27dc26a
https://doi.org/10.1007/978-3-642-76829-3_39
https://doi.org/10.1007/978-3-642-76829-3_39
Publikováno v:
Voprosy meditsinskoi khimii. 37(6)
Cysteine-dependent proteinases were studied in a model system of rat embryonal fibroblasts which enabled to evaluate two discrete steps of malignant transformation in vitro: immortalization and tumoral transformation. Dynamics of intracellular and se