Zobrazeno 1 - 10
of 152
pro vyhledávání: '"L. Wolin"'
Autor:
Xinguo Chen, Sandra L. Wolin
Publikováno v:
RNA. 29:620-629
Transfer RNA fragments are proposed to regulate numerous processes in eukaryotes, including translation inhibition, epigenetic inheritance, and cancer. In the bacteriumSalmonella entericaserovar Typhimurium, 5′ tRNA halves ending in 2′,3′ cycli
Publikováno v:
mBio, Vol 7, Iss 1 (2016)
ABSTRACT A fascinating aspect of retroviruses is their tendency to nonrandomly incorporate host cell RNAs into virions. In addition to the specific tRNAs that prime reverse transcription, all examined retroviruses selectively package multiple host ce
Externí odkaz:
https://doaj.org/article/178ebbd60db3474db43331c45e0d8686
Publikováno v:
Annual Review of Microbiology. 74:387-407
Ro60 ribonucleoproteins (RNPs), composed of the ring-shaped Ro 60-kDa (Ro60) protein and noncoding RNAs called Y RNAs, are present in all three domains of life. Ro60 was first described as an autoantigen in patients with rheumatic disease, and Ro60 o
Publikováno v:
Nucleic Acids Res
Noncoding Y RNAs are abundant in animal cells and present in many bacteria. These RNAs are bound and stabilized by Ro60, a ring-shaped protein that is a target of autoantibodies in patients with systemic lupus erythematosus. Studies in bacteria revea
Autor:
Sandra L. Wolin, Lynne E. Maquat
Publikováno v:
Science
The numerous quality control pathways that target defective ribonucleic acids (RNAs) for degradation play key roles in shaping mammalian transcriptomes and preventing disease. These pathways monitor most steps in the biogenesis of both noncoding RNAs
Publikováno v:
Journal of Cell Biology. 218:2564-2582
A defining feature of embryonic stem cells (ESCs) is the ability to differentiate into all three germ layers. Pluripotency is maintained in part by a unique transcription network that maintains expression of pluripotency-specific transcription factor
Autor:
Sandra L. Wolin, Marco Boccitto
Publikováno v:
Crit Rev Biochem Mol Biol
Ro60, also known as SS-A or TROVE2, is an evolutionarily conserved RNA-binding protein that is found in most animal cells, approximately 5% of sequenced prokaryotic genomes and some archaea. Ro60 is present in cells as both a free protein and as a co
Autor:
Alice Telesnitsky, Sandra L. Wolin
Publikováno v:
Viruses, Vol 8, Iss 8, p 235 (2016)
As they assemble, retroviruses encapsidate both their genomic RNAs and several types of host RNA. Whereas limited amounts of messenger RNA (mRNA) are detectable within virion populations, the predominant classes of encapsidated host RNAs do not encod
Externí odkaz:
https://doaj.org/article/0080472945a249748c1ddea41c01c8e3
Autor:
Sandra L. Wolin, Sandra G. Williams
Publikováno v:
Trends Mol Med
Although autoimmunity and autoimmune disease (AID) are relatively common, the repertoire of autoantigens is paradoxically very limited. Highly enriched in this autoantigen repertoire are nucleic acids and their binding proteins, which together form l
Autor:
Brian Calingaert, Zdravko P. Vassilev, Elizabeth Andrews, Nada Djokanovic, Paul Petraro, Eric Davenport, Vito S. Racanelli, Laurie J. Zografos, Dan L. Wolin, Kelly Hollis
Publikováno v:
Pharmaceutical medicine. 33(3)
As part of the risk-management plan (RMP) for aflibercept, materials have been developed to educate physicians in Canada on the key safety information and safe use for aflibercept. The objectives of this study were to assess whether physicians in Can