Zobrazeno 1 - 10
of 83
pro vyhledávání: '"L. Wingfield"'
Autor:
Isabel Espadas, Jenna L. Wingfield, Yoshihisa Nakahata, Kaushik Chanda, Eddie Grinman, Ilika Ghosh, Karl E. Bauer, Bindu Raveendra, Michael A. Kiebler, Ryohei Yasuda, Vidhya Rangaraju, Sathyanarayanan Puthanveettil
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Long noncoding RNAs (lncRNAs) play crucial roles in maintaining cell homeostasis and function. However, it remains largely unknown whether and how neuronal activity impacts the transcriptional regulation of lncRNAs, or if this leads to synap
Externí odkaz:
https://doaj.org/article/b3b16eadd75b46a39a05aa39546e135f
Molecular motor KIF3B in the prelimbic cortex constrains the consolidation of contextual fear memory
Autor:
Nadine F. Joseph, Aya Zucca, Jenna L. Wingfield, Isabel Espadas, Damon Page, Sathyanarayanan V. Puthanveettil
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-12 (2021)
Abstract Molecular and cellular mechanisms underlying the role of the prelimbic cortex in contextual fear memory remain elusive. Here we examined the kinesin family of molecular motor proteins (KIFs) in the prelimbic cortex for their role in mediatin
Externí odkaz:
https://doaj.org/article/d2983862208b4be4bb6b9ada8da8de19
Autor:
Yan-Xia Liu, Bin Xue, Wei-Yue Sun, Jenna L Wingfield, Jun Sun, Mingfu Wu, Karl F Lechtreck, Zhenlong Wu, Zhen-Chuan Fan
Publikováno v:
eLife, Vol 10 (2021)
Certain ciliary signaling proteins couple with the BBSome, a conserved complex of Bardet–Biedl syndrome (BBS) proteins, to load onto retrograde intraflagellar transport (IFT) trains for their removal out of cilia in Chlamydomonas reinhardtii. Here,
Externí odkaz:
https://doaj.org/article/e01318a578cb49e394f5023f5facabc1
Akademický článek
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Autor:
Jenna L Wingfield, Ilaria Mengoni, Heather Bomberger, Yu-Yang Jiang, Jonathon D Walsh, Jason M Brown, Tyler Picariello, Deborah A Cochran, Bing Zhu, Junmin Pan, Jonathan Eggenschwiler, Jacek Gaertig, George B Witman, Peter Kner, Karl Lechtreck
Publikováno v:
eLife, Vol 6 (2017)
Intraflagellar transport (IFT) trains, multimegadalton assemblies of IFT proteins and motors, traffic proteins in cilia. To study how trains assemble, we employed fluorescence protein-tagged IFT proteins in Chlamydomonas reinhardtii. IFT-A and motor
Externí odkaz:
https://doaj.org/article/d5e81191a8b840c585d4a90e0e20d613
Autor:
Jun Sun, Bin Dong, Zhen-Chuan Fan, Yan-Xia Liu, Jenna L Wingfield, Karl F. Lechtreck, Mingfu Wu, Bin Xue
Publikováno v:
Proc Natl Acad Sci U S A
Bardet-Biedl syndrome (BBS) is a ciliopathy caused by defects in the assembly or distribution of the BBSome, a conserved protein complex. The BBSome cycles via intraflagellar transport (IFT) through cilia to transport signaling proteins. How the BBSo
Molecular motor KIF3B in the prelimbic cortex constrains the consolidation of contextual fear memory
Autor:
Isabel Espadas, Jenna L. Wingfield, Sathyanarayanan V. Puthanveettil, Nadine F. Joseph, Damon T. Page, Aya Zucca
Publikováno v:
Molecular Brain
Molecular Brain, Vol 14, Iss 1, Pp 1-12 (2021)
Molecular Brain, Vol 14, Iss 1, Pp 1-12 (2021)
Molecular and cellular mechanisms underlying the role of the prelimbic cortex in contextual fear memory remain elusive. Here we examined the kinesin family of molecular motor proteins (KIFs) in the prelimbic cortex for their role in mediating context
Publikováno v:
The British Journal of Surgery
Introduction Covid-19 is a global threat which had emerged rapidly over the course of last year and is particularly deleterious to those with multiple co-morbidities. While limited data is available on the outcomes of emergency surgical patients infe
Autor:
Dennis R. Diener, Jenna L Wingfield, Betlehem Mekonnen, Ilaria Mengoni, Mareike A Jordan, Peiwei Liu, Karl F. Lechtreck, Gaia Pigino
Publikováno v:
Journal of Cell Science
J Cell Sci
J Cell Sci
Flagellar assembly depends on intraflagellar transport (IFT), a bidirectional motility of protein carriers, the IFT trains. The trains are periodic assemblies of IFT-A and IFT-B subcomplexes and the motors kinesin-2 and IFT dynein. At the tip, antero
Publikováno v:
British Journal of Surgery. 108
Introduction Throughout the Covid-19 pandemic, the surgical community has attempted to address whether it is safe to continue surgery. The aim of this research was to review evidence on emergency general patients operated on during the pandemic compa