Zobrazeno 1 - 10
of 4 191
pro vyhledávání: '"L. West"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The role of the cerebral cortex in self-initiated versus sensory-driven movements is central to understanding volitional action. Whether the differences in these two movement classes are due to specific cortical areas versus more cortex-wide
Externí odkaz:
https://doaj.org/article/95bc10f965b24aedb3e714103cd2ae38
Autor:
T. Curtis Shoyer, Kasie L. Collins, Trevor R. Ham, Aaron T. Blanchard, Juilee N. Malavade, Benjamin A. Johns, Jennifer L. West, Brenton D. Hoffman
Publikováno v:
Cell Reports: Methods, Vol 4, Iss 7, Pp 100815- (2024)
Summary: The ability of cells to sense and respond to mechanical forces is critical in many physiological and pathological processes. However, determining the mechanisms by which forces affect protein function inside cells remains challenging. Motiva
Externí odkaz:
https://doaj.org/article/1d829633ca9349298a176df6ee0bbc11
Autor:
Karen-Anne McVey Neufeld, Yu-Kang Mao, Christine L. West, Matthew Ahn, Hashim Hameed, Eiko Iwashita, Andrew M. Stanisz, Paul Forsythe, Denise Barbut, Michael Zasloff, Wolfgang A. Kunze
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Vagus nerve signaling is a key component of the gut-brain axis and regulates diverse physiological processes that decline with age. Gut to brain vagus firing patterns are regulated by myenteric intrinsic primary afferent neuron (IPAN) to vag
Externí odkaz:
https://doaj.org/article/8c5b201dc8a74a0aba5a9b43a60e69cf
Autor:
Aleš Linhart, Gabriela Dostálová, Kathy Nicholls, Michael L. West, Camilla Tøndel, Ana Jovanovic, Pilar Giraldo, Bojan Vujkovac, Tarekegn Geberhiwot, Einat Brill-Almon, Sari Alon, Raul Chertkoff, Rossana Rocco, Derralynn Hughes
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-12 (2023)
Abstract Background Pegunigalsidase alfa is a novel, PEGylated α-galactosidase-A enzyme-replacement therapy approved in the EU and US to treat patients with Fabry disease (FD). Objective/methods BRIDGE is a phase 3 open-label, switch-over study desi
Externí odkaz:
https://doaj.org/article/08a93d1d21254bb38a521c49dce3c679
Autor:
Mansooreh Jamshidian-Tehrani, Hossein Ghahvehchian, Christopher J Compton, Jeremy D Clark, Nicole L West, Mohsen Bahmani Kashkouli
Publikováno v:
International Journal of Ophthalmology, Vol 17, Iss 8, Pp 1576-1576 (2024)
Externí odkaz:
https://doaj.org/article/97db0435ce774c2ab12f8711dc844444
Publikováno v:
Frontiers in Virtual Reality, Vol 5 (2024)
Externí odkaz:
https://doaj.org/article/fdf763f9b112459eb775d83b0a3b4217
Autor:
Ilan A. Kerman, Matthew E. Glover, Yezhe Lin, Jennifer L. West, Alexandra L. Hanlon, Anita S. Kablinger, Sarah M. Clinton
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Objective: This study sought to investigate the relationship between antibiotic exposure and subsequent risk of psychiatric disorders.Methods: This retrospective cohort study used a national database of 69 million patients from 54 large healthcare or
Externí odkaz:
https://doaj.org/article/15f0cc8a6ff24440ab0882b87147f246
Publikováno v:
Asian Fisheries Science, Vol 14, Iss 1 (2001)
Externí odkaz:
https://doaj.org/article/58d1cf50a2ae49cdb46b0c5250185df3
Autor:
Lauren Jennings, Rebecca L. West, Nafisa Halim, Jeanette L. Kaiser, Marya Gwadz, William B. MacLeod, Allen L. Gifford, Jessica E. Haberer, Catherine Orrell, Lora L. Sabin
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background South Africa bears a large HIV burden with 7.8 million people with HIV (PWH). However, due to suboptimal antiretroviral therapy (ART) adherence and retention in care, only 66% of PWH in South Africa are virally suppressed. Standar
Externí odkaz:
https://doaj.org/article/41977d481ce743e98efbb46282851c94
Autor:
Amr H. Saleh, Michael Rothe, Dwayne L. Barber, William M. McKillop, Graeme Fraser, Chantal F. Morel, Axel Schambach, Christiane Auray-Blais, Michael L. West, Aneal Khan, Daniel H. Fowler, C. Anthony Rupar, Ronan Foley, Jeffrey A. Medin, Armand Keating
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 28, Iss , Pp 262-271 (2023)
The safety and efficacy of lentivirus-mediated gene therapy was recently demonstrated in five male patients with Fabry disease—a rare X-linked lysosomal storage disorder caused by GLA gene mutations that result in multiple end-organ complications.
Externí odkaz:
https://doaj.org/article/94ca546755434fd5983165124cd0e623