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pro vyhledávání: '"L. Weiselberg"'
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Akademický článek
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Autor:
L. C. De Marco, D. R. Budman, C. Lathia, P. Amorusi, M. Birkhofer, S. Lichtman, L. Weiselberg, V. Vinciguerra, J. Lovecchio, D. Gal, A. Hoffman, J. Kantrowitz, R. Rastogi
Publikováno v:
Cancer chemotherapy and pharmacology. 36(1)
Zeniplatin, a more water-soluble organoplatinum than cisplatin, was evaluated for clinical pharmacology in the context of a phase II trial in previously treated patients with ovarian carcinoma. A total of 12 patients were given zeniplatin at 120 mg/m
Publikováno v:
Cancer Research. 69:3089-3089
Background:Breast cancer cell lines achieve a state of resistance to antiestrogens and to estrogen withdrawal or aromatase inhibitors by utilizing other growth factor pathways to transactivate ERα and undergo estrogen-independent growth. Breast canc
Autor:
W, Kreis, D R, Budman, K, Chan, S L, Allen, P, Schulman, S, Lichtman, L, Weiselberg, M, Schuster, J, Freeman, S, Akerman
Publikováno v:
Leukemia. 5(11)
Thirty two patients with refractory or recurrent acute leukemia or blast crisis of chronic myelocytic leukemia were treated with 1-beta-D-arabinofuranosylcytosine (Ara-C), 100 mg/m2 [group I (n = 15)] or 200 mg/m2 [group II (n = 18)], and tetrahydrou
Autor:
L, Weiselberg, U, Matulonis, E, McGarvey, B, Roberts, S, Lichtman, S, Allen, V, Vinciguerra, S, Teichberg
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 63(3)
The stereologic characteristics of monocytes from patients with acute nonlymphocytic leukemia containing a monocytic component (FAB M4 and M5), and the monocytes from normal individuals were determined by morphometric analysis. The cells studied were
Publikováno v:
Cancer treatment reports. 67(10)
A phase II trial of mitomycin, vinblastine, and cisplatin was undertaken in 26 patients with non-small cell carcinoma of the lung. A major response rate of 46% was seen in measurable and evaluable disease, with a complete response rate of 12%. Median
Autor:
W, Kreis, F, Chaudhri, K, Chan, S, Allen, D R, Budman, P, Schulman, L, Weiselberg, J, Freeman, M, Deere, V, Vinciguerra
Publikováno v:
Cancer research. 45(12 Pt 1)
The pharmacokinetic parameters of low dose 1-beta-D-arabinofuranosylcytosine (ara-C) infusions were studied in 11 patients, 6 males and 5 females, with a mean age of 68.5 +/- 13.8 (SD) years. The drug was infused to 4 patients with pre-leukemia (refr
Publikováno v:
Cancer treatment reports. 66(1)
A role for vinblastine (VBL) in lung cancer has never been clearly defined. Because of recent pharmacokinetic data suggesting a biweekly schedule for VBL and recent antitumor activity shown for vindesine, a phase II trial of divided-dose VBL was init
Autor:
W, Kreis, K, Chan, D R, Budman, P, Schulman, S, Allen, L, Weiselberg, S, Lichtman, V, Henderson, J, Freeman, M, Deere
Publikováno v:
Cancer research. 48(5)
When 1-beta-D-arabinofuranosylcytosine (ara-C), 25 mg/m2, is infused over 3 h together with tetrahydrouridine (THU) at 10 to 350 mg/m2 to heavily pretreated patients with solid tumors, Michaelis-Menten type kinetic values are observed with leveling o