Zobrazeno 1 - 10
of 41
pro vyhledávání: '"L. Van der Spek"'
Autor:
L. Van der Spek, B. G. J. S. Sonneveld
Publikováno v:
Journal of Health, Population and Nutrition, Vol 43, Iss 1, Pp 1-15 (2024)
Abstract Background Timor-Leste’s food insecurity, propelled by political conflicts, a fragile economy and biophysical limitations that characterize mountainous Small Island Developing States (SIDS), is expressed in a high incidence (50%) of stunte
Externí odkaz:
https://doaj.org/article/5cc8be629ec04434885c484f78294a1f
Akademický článek
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Background: Patients with chronic lymphocytic leukemia (CLL) may be more susceptible to COVID-19 related poor outcomes, including thrombosis and death, due to the advanced age, the presence of comorbidities, and the disease and treatment- related imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::edcfbb63486e80d26627f3502ca9bb04
https://www.bib.irb.hr/1253909
https://www.bib.irb.hr/1253909
Akademický článek
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Publikováno v:
Pediatric Radiology. 47:750-754
Image-guided biopsy techniques are widely used in clinical practice. Commonly used methods employ either ultrasound (US) or computed tomography (CT) for image guidance. In certain patients, US or CT guidance may be suboptimal, or even impossible, bec
Autor:
Thommey P. Thomas, Seok-Ki Choi, James R. Baker, Alina Kotlyar, Abraham F. L. Van Der Spek, Pascale Leroueil
Publikováno v:
The Journal of Physical Chemistry B. 116:10387-10397
Oximes are important in the treatment of organophosphate (OP) poisoning, but have limited biological half-lives. Complexing these drugs with a macromolecule, such as a dendrimer, could improve their pharmacokinetics. The present study investigates th
Autor:
Ming Hsin Li, Ankur Desai, Hong Zong, James R. Baker, Pascale Leroueil, Seok-Ki Choi, Abraham F. L. Van Der Spek
Publikováno v:
Macromolecules. 44:4026-4029
Autor:
Kevin K. Tremper, Paul E. Kazanjian, Abraham F. L. Van Der Spek, Michael O'Reilly, Sachin Kheterpal
Publikováno v:
Seminars in Anesthesia, Perioperative Medicine and Pain. 23:72-85
Autor:
Alina Kotlyar, Baohua Huang, Pascale R. Leroueil, Thommey P. Thomas, Mark Vartanian, James R. Baker, Ankur Desai, Hong Zong, Brent B. Ward, Abraham F. L. Van Der Spek, Xiangyang Shi, Xue-Min Cheng
Publikováno v:
Pharmaceutical research. 30(1)
Design and evaluate the in vitro and in vivo efficacy of two extended release morphine formulations developed for IV administration by complexing esterase activated morphine prodrugs to surface-modified, generation 5 (G5) poly(amidoamine) (PAMAM) den
Autor:
Abraham F. L. Van Der Spek, Thomas Dunham, Ankur Desai, Hong Zong, Xue-Min Cheng, Alina Kotlyar, Brent B. Ward, Baohua Huang, Pascale R. Leroueil, James R. Baker, Thommey P. Thomas
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(21)
Two morphine prodrugs (‘PDA’ and ‘PDB’) were synthesized and the kinetics of esterase-mediated morphine release from these prodrugs were determined when incubated with plasma from different animal species. Morphine was rapidly released from P