Zobrazeno 1 - 10
of 273
pro vyhledávání: '"L. VECELLIO"'
Autor:
Stefan Knapp, Jürg Schwaller, Rab Prinjha, Tony Kouzarides, Nicholas B. La Thangue, Marjeta Urh, Danette L. Daniels, Duncan Hay, Susanne Müller, Sharlene Velichko, Alison O'Mahony, Paul E. Brennan, Chas Bountra, Matteo L. Vecellio, Simon Taylor, Philip Jeffrey, Dave Lugo, Kevin Lee, Nigel Parr, Umesh Kumar, Samuel Robson, Andrew Bannister, Ka Hing Che, Christopher Wells, Clarence Yapp, Panagis Filippakopoulos, Anthony Tumber, Martin Philpott, Sarah Martin, Octovia Monteiro, Heidi Olzscha, Julia Meier, Katherine Jones, Katharina Leonards, Angeliki Thanasopoulou, Oleg Fedorov, Sarah Picaud
Description of additional methods and procedures used in the study. Also includes Supplemental References.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57235f2b6dacb19e5e6c1bbf5652d40c
https://doi.org/10.1158/0008-5472.22406324
https://doi.org/10.1158/0008-5472.22406324
Autor:
Stefan Knapp, Jürg Schwaller, Rab Prinjha, Tony Kouzarides, Nicholas B. La Thangue, Marjeta Urh, Danette L. Daniels, Duncan Hay, Susanne Müller, Sharlene Velichko, Alison O'Mahony, Paul E. Brennan, Chas Bountra, Matteo L. Vecellio, Simon Taylor, Philip Jeffrey, Dave Lugo, Kevin Lee, Nigel Parr, Umesh Kumar, Samuel Robson, Andrew Bannister, Ka Hing Che, Christopher Wells, Clarence Yapp, Panagis Filippakopoulos, Anthony Tumber, Martin Philpott, Sarah Martin, Octovia Monteiro, Heidi Olzscha, Julia Meier, Katherine Jones, Katharina Leonards, Angeliki Thanasopoulou, Oleg Fedorov, Sarah Picaud
The histone acetyltransferases CBP/p300 are involved in recurrent leukemia-associated chromosomal translocations and are key regulators of cell growth. Therefore, efforts to generate inhibitors of CBP/p300 are of clinical value. We developed a specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40435e054abe8c3438258da01486a385
https://doi.org/10.1158/0008-5472.c.6507044
https://doi.org/10.1158/0008-5472.c.6507044
Autor:
Stefan Knapp, Jürg Schwaller, Rab Prinjha, Tony Kouzarides, Nicholas B. La Thangue, Marjeta Urh, Danette L. Daniels, Duncan Hay, Susanne Müller, Sharlene Velichko, Alison O'Mahony, Paul E. Brennan, Chas Bountra, Matteo L. Vecellio, Simon Taylor, Philip Jeffrey, Dave Lugo, Kevin Lee, Nigel Parr, Umesh Kumar, Samuel Robson, Andrew Bannister, Ka Hing Che, Christopher Wells, Clarence Yapp, Panagis Filippakopoulos, Anthony Tumber, Martin Philpott, Sarah Martin, Octovia Monteiro, Heidi Olzscha, Julia Meier, Katherine Jones, Katharina Leonards, Angeliki Thanasopoulou, Oleg Fedorov, Sarah Picaud
BLI evaluation of I-CBP112 selectivity (S1); BioMAP data for I-CBP112 (S2); Effects on MLL-AF9 and NUP98-HOXA9 (S3); Immunophenotype of injected MLL-AF9 cells (S4); Cell survival data (S5); Synergy with JQ1 and doxorubicin (S6).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7179d3022dddf0f23baaefb469c32d18
https://doi.org/10.1158/0008-5472.22406327.v1
https://doi.org/10.1158/0008-5472.22406327.v1
Autor:
Stefan Knapp, Jürg Schwaller, Rab Prinjha, Tony Kouzarides, Nicholas B. La Thangue, Marjeta Urh, Danette L. Daniels, Duncan Hay, Susanne Müller, Sharlene Velichko, Alison O'Mahony, Paul E. Brennan, Chas Bountra, Matteo L. Vecellio, Simon Taylor, Philip Jeffrey, Dave Lugo, Kevin Lee, Nigel Parr, Umesh Kumar, Samuel Robson, Andrew Bannister, Ka Hing Che, Christopher Wells, Clarence Yapp, Panagis Filippakopoulos, Anthony Tumber, Martin Philpott, Sarah Martin, Octovia Monteiro, Heidi Olzscha, Julia Meier, Katherine Jones, Katharina Leonards, Angeliki Thanasopoulou, Oleg Fedorov, Sarah Picaud
I-CBP112 ΔTm data for bromodomains (S1); I-CBP112 ITC data (S2); Selectivity screening data outside BRD family (S3); ITC data (S4); Data collection and refinement statistics (S5); I-CBP112 deregulated genes 3d KASUMI-1 (S6); I-CBP112 deregulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1968754395c665786341968851738032
https://doi.org/10.1158/0008-5472.22406321
https://doi.org/10.1158/0008-5472.22406321
Publikováno v:
EMC - AKOS - Trattato di Medicina. 22:1-5
Autor:
J- R. CREPPY, M. CABRERA, J. PARDESSUS, G. ROSEAU, B. DELACHE, J. MONTHARU, L. GARANGER, F. DUCANCEL, L. VECELLIO
Les études précliniques utilisant des modèles animaux sont essentielles et dans certains cas règlementaires pour les aérosols inhalés. Le macaque a été identifié comme un modèle animal pertinent mais difficile d'accès. Dans le contexte de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eae1851d036b071d7cf77f13e7dade14
Akademický článek
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Publikováno v:
Revue des maladies respiratoires. 38(2)
Nebulization is a drug delivery mode whose prescription and application remain uncertain. A guide to good practice has been proposed by the work group on aerosol therapy of the French Society for Respiratory Diseases, so-called GAT. The previous reco
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