Zobrazeno 1 - 10
of 43
pro vyhledávání: '"L. V. Gening"'
Autor:
L. V. Gening, Konstantin Y. Kazachenko, Alena V. Makarova, Nataliya Miropolskaya, Vyacheslav Z. Tarantul
Publikováno v:
DNA Repair. 50:77-82
Y-family DNA polymerase iota (Pol ι) possesses both DNA polymerase and dRP lyase activities and was suggested to be involved in DNA translesion synthesis and base excision repair in mammals. The 129 strain of mice and its derivatives have a natural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed5e26e667448ffabb8e04aaab03448f
https://doi.org/10.1016/j.dnarep.2017.01.001
https://doi.org/10.1016/j.dnarep.2017.01.001
Publikováno v:
Biochemistry (Moscow). 82:38-45
Manganese (Mn) is crucially important for vital activity of cells and has many biological functions. Nevertheless, high doses of Mn taken up by an organism over a long period may cause neurodegenerative diseases such as manganism and Parkinsonism. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957638621f6a6101b6c63e4989086e15
https://doi.org/10.1134/s0006297917010047
https://doi.org/10.1134/s0006297917010047
Autor:
Irina V. Makarova, Vyacheslav Z. Tarantul, L. V. Gening, Konstantin Y. Kazachenko, Alexandr A. Volodin
Publikováno v:
Methods and Protocols
Methods and Protocols, Vol 3, Iss 1, p 3 (2020)
Volume 3
Issue 1
Methods and Protocols, Vol 3, Iss 1, p 3 (2020)
Volume 3
Issue 1
We propose an improved earlier described &ldquo
mirror&rdquo
method for detecting in cell nuclear extracts mutations that arise in DNA during its replication due to the misincorporation of deoxyadenosine-5&prime
monophosphate (dAMP) op
mirror&rdquo
method for detecting in cell nuclear extracts mutations that arise in DNA during its replication due to the misincorporation of deoxyadenosine-5&prime
monophosphate (dAMP) op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e55b000738e9647717a60102346a04
https://doi.org/10.3390/mps3010003
https://doi.org/10.3390/mps3010003
Publikováno v:
Molecular Genetics, Microbiology and Virology. 29:16-22
The impact of the 8 most common bivalent metal cations (Mg2+, Mn2+, Co2+, Cd2+, Zn2+, Ni2+, Ca2+, Cu2+) on the operation of the whole complex of DNA polymerases in mice brain cell extracts was tested. A decrease in the fidelity of the DNA synthesis w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d164a075a4b255ed837fbefb2ca5eef
https://doi.org/10.3103/s0891416814010030
https://doi.org/10.3103/s0891416814010030
Publikováno v:
Acta Naturae. 5:34-43
Aptamers are short single-stranded oligonucleotides that are capable of binding various molecules with high affinity and specificity. When the technology of aptamer selection was developed almost a quarter of a century ago, a suggestion was immediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b055e1296288e53117a44acc2d8099
https://doi.org/10.32607/20758251-2013-5-4-34-43
https://doi.org/10.32607/20758251-2013-5-4-34-43
Publikováno v:
Biochemistry (Moscow). 78:1137-1145
Bivalent metal cations are key components in the reaction of DNA synthesis. They are necessary for all DNA polymerases, being involved as cofactors in catalytic mechanisms of nucleotide polymerization. It is also known that in the presence of Mn2+ th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc032ad357b4edb52a1f0dc862bec03
https://doi.org/10.1134/s0006297913100088
https://doi.org/10.1134/s0006297913100088
Autor:
E. E. Grishina, Irina Makarova, A. V. Lakhin, S. I. Shram, A. S. Efremova, Vyacheslav Z. Tarantul, L. V. Gening
Publikováno v:
Molecular Genetics, Microbiology and Virology. 28:1-7
DNA polymerase iota (Pol ι) which has some peculiar features and is characterized by an extremely error prone DNA synthesis, belongs to the group of enzymes preferentially activated by Mn2+ instead of Mg2+. In this work, using misGvA method (misinco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7feeb8ea1f15319d180316c2a7861e9
https://doi.org/10.3103/s0891416813010035
https://doi.org/10.3103/s0891416813010035
Autor:
Irina Makarova, L. E. Andreeva, V V Nenasheva, L. V. Gening, Vyacheslav Z. Tarantul, A. V. Lakhin
Publikováno v:
Journal of Developmental Biology
Journal of Developmental Biology, Vol 4, Iss 1, p 6 (2016)
Journal of Developmental Biology; Volume 4; Issue 1; Pages: 6
Journal of Developmental Biology, Vol 4, Iss 1, p 6 (2016)
Journal of Developmental Biology; Volume 4; Issue 1; Pages: 6
Using a modified radiolabeled primer extension method (we named this modification misGvA—“misincorporation of G versus A”) we have investigated the DNA synthesis and repair at early and late stages of development of loach Misgurnus fossilis. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069ebc567d76240bf6769f0dde7203c2
http://europepmc.org/articles/PMC5831811
http://europepmc.org/articles/PMC5831811
Autor:
A. S. Efremova, L. V. Gening, Viacheslav Z. Tarantul, Alena V. Makarova, A. V. Lakhin, Yuri I. Pavlov, S. I. Shram, Andrei A. Kazakov
Publikováno v:
Nucleic Acid Therapeutics. 22:49-57
Human DNA-polymerase iota (Pol ι) is an extremely error-prone enzyme and the fidelity depends on the sequence context of the template. Using the in vitro systematic evolution of ligands by exponential enrichment (SELEX) procedure, we obtained an oli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e864de1c9c9374d8b544a9beccdef17
https://doi.org/10.1089/nat.2011.0324
https://doi.org/10.1089/nat.2011.0324
Autor:
Irina Makarova, V V Nenasheva, L. V. Gening, L. E. Andreeva, Alena V. Makarova, Larisa V Kozikova, Vyacheslav Z. Tarantul, N. V. Khaidarova, Andrey Kazakov
Publikováno v:
Biotechnology Letters. 34:205-212
Human DNA polymerase iota (Pol ι) is a Y-family DNA polymerase with unusual biochemical properties and not fully understood functions. Pol ι preferentially incorporates dGTP opposite template thymine. This property can be used to monitor Pol ι act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc8954bfba72d7469cf5455e6cd3d6f4
https://doi.org/10.1007/s10529-011-0764-8
https://doi.org/10.1007/s10529-011-0764-8