Zobrazeno 1 - 10
of 196
pro vyhledávání: '"L. Toca"'
Autor:
Xavier García-Massó, Israel Villarrasa-Sapiña, Nuria Ortega-Benavent, Sergio Montalt-García, José L. Toca-Herrera
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract This manuscript aims to study the reliability of different variables related to performance and acceleration during the golf putt in players with medium-to-high handicaps and to determine the number of attempts necessary to find reliable val
Externí odkaz:
https://doaj.org/article/c04f37042cc64da2bacd460228cf8661
Advanced Quantification of Receptor–Ligand Interaction Lifetimes via Single-Molecule FRET Microscopy
Autor:
Lukas Schrangl, Vanessa Mühlgrabner, René Platzer, Florian Kellner, Josephine Wieland, Reinhard Obst, José L. Toca-Herrera, Johannes B. Huppa, Gerhard J. Schütz, Janett Göhring
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 1001 (2024)
Receptor–ligand interactions at cell interfaces initiate signaling cascades essential for cellular communication and effector functions. Specifically, T cell receptor (TCR) interactions with pathogen-derived peptides presented by the major histocom
Externí odkaz:
https://doaj.org/article/f6adba3fa60549a596c4b8d1a3fc9875
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Cell mechanical properties have been proposed as label free markers for diagnostic purposes in diseases such as cancer. Cancer cells show altered mechanical phenotypes compared to their healthy counterparts. Atomic Force Microscopy (AFM) is
Externí odkaz:
https://doaj.org/article/43d7274bba23475e818084d8ee1d905e
Autor:
Ina Buchholz, Thomas McDonnell, Peter Nestler, Sudarat Tharad, Martin Kulke, Anna Radziszewska, Vera M. Ripoll, Frank Schmidt, Elke Hammer, Jose L. Toca-Herrera, Anisur Rahman, Mihaela Delcea
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Beta-2-glycoprotein I (β2GPI) is a blood protein and the major antigen in the autoimmune disorder antiphospholipid syndrome (APS). β2GPI exists mainly in closed or open conformations and comprises of 11 disulfides distributed across five d
Externí odkaz:
https://doaj.org/article/ab52dc10ebec4e0c9e466f4231064c67
Publikováno v:
Toxins, Vol 15, Iss 2, p 167 (2023)
Cyt proteins are insecticidal proteins originally from Bacillus thuringiensis. The lipid binding of the Cyt2Aa2 protein depends on the phase of the lipid bilayer. In this work, the importance of the conserved T144 residue in the αD-β4 loop for lipi
Externí odkaz:
https://doaj.org/article/4b962f7cf1db4360a3c7a1383e6d6c6b
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract The interest in studying the mechanical and adhesive properties of cells has increased in recent years. The cytoskeleton is known to play a key role in cell mechanics. However, the role of the microtubules in shaping cell mechanics is not ye
Externí odkaz:
https://doaj.org/article/fe5caa122b88497798f54afea2ec8a10
Akademický článek
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Autor:
Maria Maares, Claudia Keil, Leif Löher, Andreas Weber, Amsatou Andorfer-Sarr, Hajo Haase, Jagoba Iturri, José L. Toca-Herrera
Publikováno v:
Biology, Vol 9, Iss 12, p 468 (2020)
Monitoring biomechanics of cells or tissue biopsies employing atomic force microscopy (AFM) offers great potential to identify diagnostic biomarkers for diseases, such as colorectal cancer (CRC). Data on the mechanical properties of CRC cells, howeve
Externí odkaz:
https://doaj.org/article/f721b7c205bf405c8a4c735b6a7a251f
Publikováno v:
Toxins, Vol 12, Iss 4, p 226 (2020)
Cytolytic toxin (Cyt) is a toxin among Bacillus thuringiensis insecticidal proteins. Cyt toxin directly interacts with membrane lipids for cytolytic action. However, low hemolytic activity is desired to avoid non-specific effects in mammals. In this
Externí odkaz:
https://doaj.org/article/b7a5d586020a40e680c5e14ca1c3ebb4
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 38(50)
Bacterial cells survive in a wide range of different environments and actively tune their mechanical properties for purposes of growth, movement, division, and nutrition. In Gram-negative bacteria, the cell envelope with its outer membrane and peptid