Zobrazeno 1 - 10
of 35
pro vyhledávání: '"L. Susan Pletscher"'
Autor:
Heather A. Lawson, Kathleen M. Zelle, Gloria L. Fawcett, Bing Wang, L. Susan Pletscher, Taylor J. Maxwell, Thomas H. Ehrich, Jane P. Kenney-Hunt, Jason B. Wolf, Clay F. Semenkovich, James M. Cheverud
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 10, Pp 2976-2984 (2010)
Variation in serum cholesterol, free-fatty acids, and triglycerides is associated with cardiovascular disease (CVD) risk factors. There is great interest in characterizing the underlying genetic architecture of these risk factors, because they vary g
Externí odkaz:
https://doaj.org/article/7036436aa0c54a2290ef5df5a74bbaac
Autor:
James M. Cheverud, Gloria L. Fawcett, Joseph P. Jarvis, Elizabeth A. Norgard, Mihaela Pavlicev, L. Susan Pletscher, Kenneth S. Polonsky, Honggang Ye, Graeme I. Bell, Clay F. Semenkovich
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 5, Pp 907-913 (2010)
We previously mapped Adip1, an obesity quantitative trait locus (QTL), to the central portion of murine chromosome 1 containing the calpain-10 (Capn10) gene. Human studies have associated calpain-10 (CAPN10) variants with type 2 diabetes and various
Externí odkaz:
https://doaj.org/article/c79151826d384ca698b1bb5170264cac
Autor:
Joseph P. Jarvis, Jane Kenney-Hunt, Thomas H. Ehrich, L. Susan Pletscher, Clay F. Semenkovich, James M. Cheverud
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 8, Pp 1692-1702 (2005)
Maternal effects on offspring phenotypes occur because mothers in many species provide an environment for their developing young. Although these factors are correctly “environmental” with respect to the offspring genome, their variance may have b
Externí odkaz:
https://doaj.org/article/e699757ed32e49489abf65a8eac25fba
Autor:
Melissa G. Kramer, Ty T. Vaughn, L. Susan Pletscher, Kelly King-Ellison, Emily Adams, Christopher Erikson, James M. Cheverud
Publikováno v:
Genetics and Molecular Biology, Vol 21, Iss 2, p 211 (1998)
Strain intercross experiments provide a powerful means for mapping genes affecting complex quantitative traits. We report on the genetic variability of the intercross of the Large (LG/J) and Small (SM/J) inbred mouse strains as a guide to gene mappin
Externí odkaz:
https://doaj.org/article/7a52956a09c44a2298a13a870d69e041
Autor:
Arthur Lee, Bing Wang, L. Susan Pletscher, Gloria L. Fawcett, Thomas H. Ehrich, Heather A. Lawson, Taylor J. Maxwell, Jane P. Kenney-Hunt, Jason B. Wolf, Clay F. Semenkovich, James M. Cheverud
Publikováno v:
Mammalian Genome. 22:197-208
Variations in diabetic phenotypes are caused by complex interactions of genetic effects, environmental factors, and the interplay between the two. We tease apart these complex interactions by examining genome-wide genetic and epigenetic effects on di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d401aec77e1fc3e31c8f9125c5952de7
https://doi.org/10.1007/s00335-010-9313-3
https://doi.org/10.1007/s00335-010-9313-3
Autor:
Heather A. Lawson, Jason B. Wolf, Victoria R. Brooks, James M. Cheverud, Elizabeth A. Norgard, L. Susan Pletscher, Bing Wang
Publikováno v:
Mammalian Genome. 22:178-196
Previous studies on the LG,SM advanced intercross line have identified approximately 40 quantitative trait loci (QTL) for long -bone (humerus, ulna, femur, and tibia) lengths. In this study, long-bone-length QTL were fine-mapped in the F(34) generati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69bb2037fe06efd3a4faf089ad0e5910
https://doi.org/10.1007/s00335-010-9311-5
https://doi.org/10.1007/s00335-010-9311-5
Autor:
Lise Clark, Andrew V. Kossenkov, Ellen Heber-Katz, L. Susan Pletscher, Elizabeth P. Blankenhorn, Celia Chang, James M. Cheverud, Louise C. Showe, Gregory Bryan, Wenhwai Horng, Xiang-Ming Zhang
Publikováno v:
Mammalian Genome. 20:720-733
MRL mice display unusual healing properties. When MRL ear pinnae are hole punched, the holes close completely without scarring, with regrowth of cartilage and reappearance of both hair follicles and sebaceous glands. Studies using (MRL/lpr x C57BL/6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d708b93479a945fc2d17515941bc89c
https://doi.org/10.1007/s00335-009-9216-3
https://doi.org/10.1007/s00335-009-9216-3
Autor:
L. Susan Pletscher, James M. Cheverud, Joseph P. Jarvis, Thomas H. Ehrich, Clay F. Semenkovich, Jane P. Kenney-Hunt
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 8, Pp 1692-1702 (2005)
Maternal effects on offspring phenotypes occur because mothers in many species provide an environment for their developing young. Although these factors are correctly "environmental" with respect to the offspring genome, their variance may have both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e707b57993269d3c2a00fae809483be
http://www.sciencedirect.com/science/article/pii/S0022227520329680
http://www.sciencedirect.com/science/article/pii/S0022227520329680
Autor:
Jane P. Kenney, Tomas Hrbek, Thomas H. Ehrich, James M. Cheverud, Clay F. Semenkovich, L. Susan Pletscher
Publikováno v:
Diabetes. 53:3328-3336
Genetic variation in response to high-fat diets is important in understanding the recent secular trends that have led to increases in obesity and type 2 diabetes. The examination of quantitative trait loci (QTLs) for both obesity- and diabetes-relate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71cc8113ff5a6066e65578831b6e6312
https://doi.org/10.2337/diabetes.53.12.3328
https://doi.org/10.2337/diabetes.53.12.3328
Publikováno v:
Diabetes. 53:2700-2708
Obesity and its comorbidities, particularly type 2 diabetes, have become serious public health problems over the past few decades. Although the current pandemic is largely caused by societal environmental changes in diet, variation in response to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2438e803f70369471b59cac506fade48
https://doi.org/10.2337/diabetes.53.10.2700
https://doi.org/10.2337/diabetes.53.10.2700