Zobrazeno 1 - 10
of 39
pro vyhledávání: '"L. Stoops"'
Autor:
Terry L. Stoops
Publikováno v:
The Journal of the Civil War Era. 6:293-295
Publikováno v:
Journal of Membrane Science. 471:168-178
Polyvinylpyrrolidone free and thus more sustainable polyethersulfone ultrafiltration membrane were successfully synthesized by the incorporation of high amounts inorganic nanoparticles into the polymeric matrix. The effect of the filler content on pa
Publikováno v:
HVAC&R Research. 19:1001-1015
The indoor climate in commercial kitchens is often unsatisfactory, and working conditions can have a significant effect on employees’ comfort and productivity. The type of establishment (fast food, casual, etc.) and climatic zone can influence ther
Publikováno v:
ACS Chemical Neuroscience. 3:658-664
The synthesis of phidianidines A and B, the first 1,2,4-oxadiazole-containing alkaloid, from the marine opisthobranch mollusk Phidiana militaris is reported. The synthesis proceeds in six steps from known indole acetic acids in 39.9% (phidianidine A)
Publikováno v:
Expert Opinion on Therapeutic Patents. 21:1309-1338
Akt plays a pivotal role in cell survival and proliferation through a number of downstream effectors; unregulated activation of the PI3K/PTEN/Akt pathway is a prominent feature of many human cancers. Akt is considered an attractive target for cancer
Autor:
Emily Days, Sydney L. Stoops, Chris Farmer, Suzanne N. Brady, A. Scott Pearson, C. David Weaver, R. Daniel Beauchamp, Craig W. Lindsley, Alex G. Waterson, Connie Weaver
Publikováno v:
ACS Chemical Biology. 6:452-465
E-cadherin is a transmembrane protein that maintains intercellular contacts and cell polarity in epithelial tissue. The down-regulation of E-cadherin contributes to the induction of the epithelial-to-mesenchymal transition (EMT), resulting in an incr
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:5207-5211
Herein we disclose the first total synthesis of tambjamine K and a library of unnatural analogs. Unnatural analogs were shown to be more potent in viability, proliferation, and invasion assays than the natural product in multiple cancer cell lines, w
Autor:
Robert R. Lavieri, Jana A. Lewis, Paige E. Selvy, Michelle D. Armstrong, Jason R. Buck, Craig W. Lindsley, H. Alex Brown, Sydney L. Stoops, Sarah A. Scott
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:1916-1920
This Letter describes the synthesis and structure-activity-relationships (SAR) of isoform-selective PLD inhibitors. By virtue of the installation of alternative halogenated piperidinyl benzimidazolone privileged structures, in combination with a key
Autor:
Thomas Kodadek, Todd M. Doran, Alberto Pugliese, Lorraine F. Clark, Kevin Pels, Sydney L. Stoops, Jay S. Skyler, Scott Simanski, Eric Koesema, Jumpei Morimoto
Publikováno v:
Cell chemical biology. 23(5)
A major goal in understanding autoimmune diseases is to define the antigens that elicit a self-destructive immune response, but this is a difficult endeavor. In an effort to discover autoantigens associated with type 1 diabetes (T1D), we used epitope
Autor:
Alex G. Waterson, Hanbing An, Sydney L. Stoops, J. Scott Daniels, R. Daniel Beauchamp, John T. Brogan, Craig W. Lindsley, Suzanne Brady, Connie Weaver
Publikováno v:
Bioorganicmedicinal chemistry letters. 25(19)
E-cadherin is a ubiquitous trans-membrane protein that has important functions in cellular contacts and has been shown to play a role in the epithelial mesenchymal transition. We have previously reported the use of an HTS screen to identify compounds