Zobrazeno 1 - 10
of 221
pro vyhledávání: '"L. Stefaneanu"'
Autor:
K. Kovacs, L. Stefaneanu
Publikováno v:
Cells Tissues Organs. 152:19-27
In transgenic mice with cerebral expression of foreign GH, pituitary GH production is profoundly disturbed, blood IGF-I levels are decreased and growth is retarded. Adenohypophysial morphology in these transgenic mice (6 males and 6 females) was stud
Autor:
L. Stefaneanu
Publikováno v:
Journal of Clinical Endocrinology & Metabolism. 78:83-88
Autor:
B W, Scheithauer, E, Horvath, K, Kovacs, R V, Lloyd, L, Stefaneanu, M, Buchfelder, R, Fahlbusch, K, von Werder, D F, Lyons
Publikováno v:
Pituitary. 1(3-4)
Recent studies indicate that cells of various epithelial tumors are capable of transformation to neurons. Observing both neurons and neuropil in two prolactin-producing adenohypophyseal tumors, one benign and one malignant, we sought to assess their
Publikováno v:
Pituitary. 1(3-4)
We studied the presence of von Hippel-Lindau protein (VHL-P) in 7 nontumorous pituitaries and 68 pituitary adenomas by immunocytochemistry using a polyclonal antibody which detects both normal and mutated forms. In nontumorous pituitary VHL-P was var
Publikováno v:
Transgenic research. 8(3)
PEPCK/bGH transgenic mice have very high blood levels of foreign GH, and prominent reproductive disturbances, especially in females. To obtain a deeper insight into the causes of these abnormalities, pituitaries of PEPCK/bGH transgenics were studied
Publikováno v:
Endocrinology. 140(9)
Pituitary is influenced by circulating and locally produced insulin-like growth factor I (IGF-I). To further elucidate the role of pituitary IGF-I, we compared pituitary morphology of homozygous (IgfI-/-), heterozygous (IgfI+/+), and wild-type (IgfI+
Publikováno v:
Virchows Archiv : an international journal of pathology. 432(3)
Insulin-like growth factors (IGFs) have been reported to promote cell proliferation in many tumours, but their contribution to pituitary adenoma development and growth has not been characterized. We report the presence of insulin-like growth factor I
Autor:
L, Stefaneanu, K, Kovacs
Publikováno v:
Microscopy research and technique. 39(2)
Transgenic mice are valuable experimental models of human endocrine diseases. Targeted ablation of specific cell lineages or insertion of genes coding for releasing factors, hormones, growth factors, and oncogenes fused with appropriate promoters, or
Autor:
A Tampanaru-Sarmesiu, L Stefaneanu, C Readhead, S Akita, Shlomo Melmed, J Fine, Kalman Kovacs
Publikováno v:
The Journal of clinical investigation. 99(10)
Leukemia inhibitory factor (LIF) and LIF receptors are expressed in adenohypophyseal cells and LIF regulates pituitary hormone transcription and cell replication in vitro. Therefore, transgenic mice expressing pituitary-directed LIF driven by the rat
Autor:
K. Kovacs, L. Stefaneanu
Publikováno v:
Endocrine System ISBN: 9783642646492
The adenohypophysis originates in a diverticulum of stomodeal ectoderm called Rathke’s pouch. A ventral evagination of diencephalon-saccus infundibula contacts Rathke’s pouch and gives rise to the neurohypophysis. The adenohypophysis has an anter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46161a1d6eb722692fe5987f9fd8f766
https://doi.org/10.1007/978-3-642-60996-1_4
https://doi.org/10.1007/978-3-642-60996-1_4