Zobrazeno 1 - 10
of 330
pro vyhledávání: '"L. Sautebin"'
Publikováno v:
Mediators of Inflammation, Vol 5, Iss 1, Pp 14-17 (1996)
The effect of prostaglandtn E2, iloprost and cAMP on both nitric oxide and tumour necrosis factor-α release in J774 macrophages has been studied. Both prostaglandin E2 and iloprost inhibited, in a concentration-dependent fashion, the lipopolysacchar
Externí odkaz:
https://doaj.org/article/6295ae5c9ffd4e0bb380c2dd92c0e753
Akademický článek
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Autor:
Carla Ghelardini, Antonio Giordani, Andrea Cappelli, Giovanna Poce, Mariangela Biava, Alma Martelli, Gianfranco Caselli, Maurizio Anzini, Sara Consalvi, L. Sautebin, A. Di Capua, Vincenzo Calderone, Maria Cristina Breschi, P. Patrignani, Lucio Claudio Rovati, Lara Testai
Publikováno v:
Pharmacological Research. 78:1-9
Selective cyclooxygenase 2 (COX2) inhibitors (COXIBs) are effective anti-inflammatory and analgesic drugs with improved gastrointestinal (GI) safety compared to nonselective nonsteroidal anti-inflammatory drugs known as traditional (tNSAIDs). However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec5e3c242dbe36bbe79dcefd10b40d8
https://doi.org/10.1016/j.phrs.2013.09.008
https://doi.org/10.1016/j.phrs.2013.09.008
Autor:
Antonietta Rossi, P. Patrignani, Carla Ghelardini, S. Alfonso, Paola Anzellotti, Gianluca Giorgi, Antonio Giordani, Di Cesare Mannelli L, Claudio Battilocchio, Giovanna Poce, Mariangela Biava, Salvatore Valenti, Annalisa Bruno, Michele Rovini, Papa G, Giulio Cesare Porretta, L. Sautebin, Anzini M, Calderone, Alma Martelli, Lara Testai
Publikováno v:
Journal of medicinal chemistry. 54(22)
The design of compounds that are able to inhibit cyclooxygenase (COX) and to release nitric oxide (NO) should give rise to drugs endowed with an overall safer profile for the gastrointestinal and cardiovascular systems. Herein we report a new class o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c531ce5629b29c5cdd1fc043bd22a2
https://pubmed.ncbi.nlm.nih.gov/21992176
https://pubmed.ncbi.nlm.nih.gov/21992176
Publikováno v:
British journal of pharmacology. 165(3)
Leukotrienes (LTs) are pro-inflammatory mediators produced by 5-lipoxygenase (5-LO). Currently available 5-LO inhibitors either lack efficacy or are toxic and novel approaches are required to establish a successful anti-LT therapy. Here we provide a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3efaf56e1eea915db1e0284bbf004299
https://pubmed.ncbi.nlm.nih.gov/21797843
https://pubmed.ncbi.nlm.nih.gov/21797843
Autor:
L. Sautebin, Maurizio Botta, Fabrizio Manetti, Michele Rovini, G. C. Porretta, Antonio Giordani, Maurizio Anzini, Claudio Battilocchio, S. Tacconelli, Antonietta Rossi, P. Patrignani, Francesco Makovec, Giovanna Poce, Nicoletta Galeotti, Carlo Pergola, Mariangela Biava, Carla Ghelardini, Paola Anzellotti, Andrea Cappelli
The development of the coxib family has represented a stimulating approach in the treatment of inflammatory disorders, such as arthritis, and for the management of acute pains, in relation to the well-known traditional Non-Steroidal Anti-inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5453c2789c7b12517804164731397978
http://hdl.handle.net/2158/586712
http://hdl.handle.net/2158/586712
Autor:
A, Rossi, C, Pergola, A, Koeberle, M, Hoffmann, F, Dehm, P, Bramanti, S, Cuzzocrea, O, Werz, L, Sautebin
BACKGROUND AND PURPOSE Zileuton is the only 5-lipoxygenase (5-LOX) inhibitor marketed as a treatment for asthma, and is often utilized as a selective tool to evaluate the role of 5-LOX and leukotrienes. The aim of this study was to investigate the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::82dcb3e2fa3488b9a0bd1c8de76466cf
http://hdl.handle.net/11588/381407
http://hdl.handle.net/11588/381407