Zobrazeno 1 - 10
of 37
pro vyhledávání: '"L. Saccar"'
Autor:
Consuelo L Saccar
Publikováno v:
Expert Opinion on Drug Metabolism & Toxicology. 5:1113-1124
Esomeprazole (S-isomer of omeprazole) demonstrates a better pharmacokinetic/pharmacodynamic profile than the racemic product omeprazole. Esomeprazole's pharmacological activity of gastric acid secretion is through proton pump inhibition. The pharmaco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f45d39b98fe530b04d52a0e381d5bb0
https://doi.org/10.1517/17425250903124363
https://doi.org/10.1517/17425250903124363
Autor:
Consuelo L. Saccar, Sandra M. Gawchik
Publikováno v:
Expert Opinion on Biological Therapy. 9:377-382
An overview of short-term specific immunotherapy (ST-SIT) highlighting Pollinex Quattro (PQ) Tree is presented. The product development of this novel allergy vaccine using modifying agent glutaraldehyde, adjuvant monophosphoryl lipid and L-tyrosine h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93883be04fd3261edbde541e490e3352
https://doi.org/10.1517/14712590802699596
https://doi.org/10.1517/14712590802699596
Publikováno v:
Journal of Allergy and Clinical Immunology. 103:615-621
Background: Limited dose-response information is available for nebulized β 2 -agonists, especially in young children. Objective: The purpose of this study was to determine the safety and efficacy of increasing doses of nebulized levalbuterol (Xopene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9f4c91c65ee79579481cb5e2aeb28a8
https://doi.org/10.1016/s0091-6749(99)70233-2
https://doi.org/10.1016/s0091-6749(99)70233-2
Publikováno v:
Pharmaceutical research. 1(5)
The effects of morphine on the single dose pharmacokinetics of theophylline were examined in two groups (6 rats/group) of male Sprague-Dawley rats after the administration of theophylline (6.25 mg/kg) alone and in conjunction with a 5 mg /kg I.V. dos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3da37581ed71a02bab1f07da880d4af0
https://pubmed.ncbi.nlm.nih.gov/24277335
https://pubmed.ncbi.nlm.nih.gov/24277335
Publikováno v:
Pharmaceutical research. 3(3)
Amiodarone is an investigational antiarrhythmic agent which has been implicated in reducing the activity of the hepatic mixed-function oxidase system. To evaluate this effect further, two groups of six male Sprague-Dawley rats each received theophyll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84990ab9577c1f466ae81291b9bd5777
https://pubmed.ncbi.nlm.nih.gov/24271523
https://pubmed.ncbi.nlm.nih.gov/24271523
Autor:
Consuelo L. Saccar, Deborah Givan, Herbert C. Mansmann, Robert Zanni, Ghassem E. Larijani, Mary Beth Kester, Mario L. Rocci, Douglas S. Holsclaw
Publikováno v:
Pediatric Asthma, Allergy & Immunology. 5:7-13
The pharmacokinetics of theophylline and its metabolites were studied in 13 patients with cystic fibrosis (CF) after an intravenous bolus of aminophylline (6 mg/kg) followed by multiple dosing with sustained release theophylline (Theo-Dur®) (7.7-14.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::845c71fc4096790a06ad4df0d8c264ec
https://doi.org/10.1089/pai.1991.5.7
https://doi.org/10.1089/pai.1991.5.7
Autor:
Consuelo L. Saccar, Sandra M. Gawchik
Publikováno v:
Drug safety. 23(4)
The efficacy of intranasal triamcinolone acetonide in seasonal and allergic rhinitis has been evaluated in clinical trials and has been compared with antihistamines and other intranasal corticosteroids. Intranasal corticosteroids are either as equall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19a691f0ee97484ce4de0146ec30156c
https://pubmed.ncbi.nlm.nih.gov/11051218
https://pubmed.ncbi.nlm.nih.gov/11051218
Autor:
S M, Gawchik, C L, Saccar
Publikováno v:
The Journal of the American Osteopathic Association. 100(1)
Leukotrienes are proinflammatory mediators with special significance in asthma. Released by numerous cell types, particularly after exposure to allergens, leukotrienes cause a potent contraction of bronchial smooth muscle, resulting in reduced airway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f00f88643ef08c4ff1c27553ed9f6ba
https://pubmed.ncbi.nlm.nih.gov/10693315
https://pubmed.ncbi.nlm.nih.gov/10693315
Autor:
Consuelo L. Saccar
Publikováno v:
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine. 9(1)
Dry powder inhaler (DPI) delivery systems provide advantages over the metered-dose inhaler (MDI) systems. Of the anti-asthma agents studied, most of the trials have focused on the beta adrenergic agonists with a lesser degree of inhaled cromoglycate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f82e76a583a5ad6dcc9c0248ccc3d1b1
https://pubmed.ncbi.nlm.nih.gov/10160213
https://pubmed.ncbi.nlm.nih.gov/10160213
Publikováno v:
The Journal of Pediatrics. 103:131-135
The elimination pharmacokinetics of tobramycin sulfate was studied in 25 newborn infants of birth weight 0.7 to 4.7 kg during 31 treatment episodes. The peak serum concentrations after a 2.5 mg/kg dose were usually within the therapeutic range of 5 t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e377c126ecdc9a80755bf91b7abae83
https://doi.org/10.1016/s0022-3476(83)80799-9
https://doi.org/10.1016/s0022-3476(83)80799-9