Zobrazeno 1 - 10
of 12
pro vyhledávání: '"L. Saafi"'
Autor:
Shaoping Zhang, Hong Liu, Winifred P. S. Wong, Garth J. S. Cooper, Athena Ferreira, Yee Soon Choong, Etuate L. Saafi, Chia Lin Chuang, David Scott
Publikováno v:
Diabetes
OBJECTIVES—We sought to 1) Determine whether soluble-misfolded amylin or insoluble-fibrillar amylin may cause or result from diabetes in human amylin transgenic mice and 2) determine the role, if any, that insulin resistance might play in these pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0a3a86e1472649e6b4cc28b2e42c5b
https://doi.org/10.2337/db06-1755
https://doi.org/10.2337/db06-1755
Publikováno v:
African Journal of Biotechnology; Vol 11, No 63 (2012); 12619-12629
The adverse effects of salt should not be the same in tobacco plants exposed to a permanent and transient high concentration of NaCl in its environment. Experiments were conducted in order to verify the hypothesis of reversibility of NaCl effects. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a78edc14d5102bb3039e44c54c54c82
https://www.ajol.info/index.php/ajb/article/view/129062
https://www.ajol.info/index.php/ajb/article/view/129062
Publikováno v:
Biochemical Journal. 343:53-61
The objective of these studies was to clarify the role of Ca(2+) in the mechanism of death evoked by human amylin (hA) in islet beta-cells. hA forms fibrils in vitro and islet amyloid in vivo. Here we show that pure synthetic hA aggregated in solutio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ec7b7a21598b69b8ebc6079c1966427
https://doi.org/10.1042/bj3430053
https://doi.org/10.1042/bj3430053
Publikováno v:
Bulletin of Health Research, Vol 12, Iss 1 Mar (2012)
Studi nyamuk penular filariasis malayi pada empat desa endemis filariasis (Wawolemo, Pondi-daha, Lalohao dan Teteona) di Kabupaten Kendari, Sulawesi Tenggara, telah dilakukan dari bulan November 1980 sampai Oktober 1982. Nyamuk penular Brugia malayi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::0a12fb3e1f861f39e2c7f00539a4be3e
http://ejournal.litbang.kemkes.go.id/index.php/BPK/article/view/557
http://ejournal.litbang.kemkes.go.id/index.php/BPK/article/view/557
Publikováno v:
Bulletin of Health Research, Vol 12, Iss 1 Mar (2012)
Studi nyamuk penular filariasis malayi pada empat desa endemis (Wawolemo. Pondidaha. Lalohao dan Teteona) di Kabupaten Kendari, Sulawesi Tenggara, telah dilakukan dari bulan November 1980 sampai Oktober 1982. Nyamuk penular Brugia malayi di alam sela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::8e7e809afda78d2486d252933d8dd5c4
http://ejournal.litbang.kemkes.go.id/index.php/BPK/article/view/558
http://ejournal.litbang.kemkes.go.id/index.php/BPK/article/view/558
Autor:
Grant R. Allen, Bridget L. Leonard, Garth J. S. Cooper, Ajith Dissanayake, F. E. Leahy, John Richard Baker, Thomas K. Borg, Etuate L. Saafi, Geraldine F. Keogh, Adèle J. Pope, Robert N. Doughty, Dianne H. Brunton, Peter D. W. Boyd, Gregory D. Gamble, Yih-Kai Chan, Sally D. Poppitt, Brett R. Cowan, Anthony R. J. Phillips, Soon Y. Choong, Alistair A. Young, Christopher J. Occleshaw, David J. Crossman
Publikováno v:
Diabetes. 53(9)
Heart disease is the major cause of death in diabetes, a disorder characterized by chronic hyperglycemia and cardiovascular complications. Although altered systemic regulation of transition metals in diabetes has been the subject of previous investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440436332f6ea790ecd279577fd2407d
https://pubmed.ncbi.nlm.nih.gov/15331567
https://pubmed.ncbi.nlm.nih.gov/15331567
Publikováno v:
Cell biology international. 25(4)
A view is emerging that human amylin (HA) kills pancreatic islet beta-cells by apoptosis. This study strengthens this view by documenting time-dependent morphological and ultrastructural changes in 10 microm HA-treated cultured RINm5F islet beta-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b6b008e2b1ec26d449f151ee77b6b5
https://pubmed.ncbi.nlm.nih.gov/11319840
https://pubmed.ncbi.nlm.nih.gov/11319840
Publikováno v:
The Biochemical journal.
The objective of these studies was to clarify the role of Ca(2+) in the mechanism of death evoked by human amylin (hA) in islet beta-cells. hA forms fibrils in vitro and islet amyloid in vivo. Here we show that pure synthetic hA aggregated in solutio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef812d3340968ee75f90e892a4b90b73
https://pubmed.ncbi.nlm.nih.gov/10493911
https://pubmed.ncbi.nlm.nih.gov/10493911
Publikováno v:
FEBS letters. 455(3)
Human amylin (10 microM) significantly inhibited RINm5F islet beta-cell proliferation and evoked apoptosis associated with typical degenerative ultrastructural changes and DNA fragmentation, whereas rat amylin did not. Time course analysis showed tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93756419ee4e2863f352021163db41b9
https://pubmed.ncbi.nlm.nih.gov/10437796
https://pubmed.ncbi.nlm.nih.gov/10437796
Autor:
Kenneth N. Goldie, Garth J. S. Cooper, W. T. M. Gruijters, Ueli Aebi, Claire Goldsbury, Shirley A. Müller, Martin P. Misur, Joerg Kistler, Andreas Engel, Etuate L. Saafi
Publikováno v:
Journal of structural biology. 119(1)
Human amylin forms fibrillar amyloid between pancreatic islet cells in patients with non-insulin-dependent (type 2) diabetes mellitus. Fibrillar assemblies also form in vitro in aqueous solutions of synthetic human amylin. We now report on the struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f58f6e2d9016be927774373d5fbb2f
https://pubmed.ncbi.nlm.nih.gov/9216085
https://pubmed.ncbi.nlm.nih.gov/9216085