Výsledky vyhledávání - "L. S. Sitnikova"

The Neuroprotective Effect of Forskolin and Its Influence of Mitochondrial Dysfunction in Neurons in Primary Rat Cerebellum Cultures

Autor: M. A. Ivanova, Sergei M. Antonov, T. V. Karelina, P. A. Abushik, L. S. Sitnikova, D. A. Sibarov

Publikováno v: Neuroscience and Behavioral Physiology. 49:1096-1099

Activation of cyclic adenosine monophosphate (cAMP) synthesis is known to lead to triggering of neuroprotective signal cascades. It is therefore interesting to assess the effects of forskolin as an activator of adenylate cyclase and cAMP production o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c295b6fb4ad6d5f7f92d2fbcc016b0e5
https://doi.org/10.1007/s11055-019-00845-6

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Collapse of Neuronal Energy Balance As a Basis of L-Homocysteine Neurotoxicity

Autor: T. V. Karelina, P. A. Abushik, L. S. Sitnikova, Sergei M. Antonov, Yu. D. Stepanenko, Rashid Giniatullin, D. A. Sibarov, M. A. Ivanova

Publikováno v: Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology. 12:360-368

Using fluorescence detection methods, neurotoxic effects of L-homocysteine (HCY), L-glutamate (Glu), and N-methyl-D-aspartate (NMDA) on primary culture of rat cerebellar neurons were compared and the agonist-evoked intracellular Ca2+ responses and ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e243e1c467749ed56a82788db0f7bbb
https://doi.org/10.1134/s1990747818050069

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Forskolin As a Neuroprotector and Modulator of Glutamate-Evoked Ca2+ Entry into Cerebellar Neurons

Autor: P. A. Abushik, Yu. D. Stepanenko, L. S. Sitnikova, D. A. Sibarov, M. A. Ivanova, T. V. Karelina, Sergei M. Antonov

Publikováno v: Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology. 12:390-393

The analysis of neuronal viability of cerebellar neurons in primary culture during long-lasting (240 min) treatment with glutamate revealed that forskolin (1 μM), an adenylate cyclase activator, prevents apoptosis and necrosis of cells, thus exhibit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b42a29800f7a64f0fe7ca70601707810
https://doi.org/10.1134/s1990747818050021

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