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pro vyhledávání: '"L. S. Premkumar"'
Autor:
L S, Premkumar, G P, Ahern
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 274(2)
3,4-Methylenedioxymethamphetamine (ecstasy, MDMA) and related amphetamines are CNS stimulants that have euphoric, memory-enhancing and neurotoxic properties. When applied in pharmacological doses to cultured rat hippocampal neurons, ecstasy reduced t
Autor:
Shin-Ho Chung, L. S. Premkumar
Publikováno v:
Neuroreport. 6(5)
Single channel potassium currents activated indirectly via stimulation of metabotropic receptors were recorded in cell-attached patches on hippocampal neurones in slices from neonatal rats. When metabotropic receptors in the area outside of the patch
Autor:
L. S. Premkumar, P. W. Gage
Publikováno v:
Journal of neurophysiology. 71(6)
1. Single-channel currents were recorded in cell-attached patches on cultured hippocampal neurons in response to gamma-aminobutyric acid-B (GABAB) agonists or serotonin applied to the cell surface outside the patch area. 2. The channels activated by
Publikováno v:
Methods in Pharmacology ISBN: 9781441932327
A wide range of neurotransmitters, such as gamma-aminobutyric acid (GABA), serotonin (5-hydroxytryptamine, 5HT), acetylcholine, noradrenaline, dopamine, and adenosine, have been found to activate potassium channels in central neurons. It is possible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc7d55042ab2355590382409c2cd313e
https://doi.org/10.1007/978-1-4757-2239-0_7
https://doi.org/10.1007/978-1-4757-2239-0_7
Publikováno v:
Proceedings. Biological sciences. 242(1303)
Exposure of the inside surface of patches of membrane excised from cultured rat hippocampal neurons to arachidonic acid (10-100 $\mu $M) caused the appearance of potassium currents of variable amplitude similar to those activated by GABA or baclofen
Publikováno v:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 329(1254)
Techniques for extracting small, single channel ion currents from background noise are described and tested. It is assumed that single channel currents are generated by a first-order, finite-state, discrete-time, Markov process to which is added 'whi
Autor:
Peter W. Gage, Subhash G. Vasudevan, Helmut Reiländer, Shin-Ho Chung, L. S. Premkumar, Sally Stowe
Publikováno v:
FEBS Letters. (1):7-11
Following the infection of insect ovarian cells (Sf9) with recombinant baculovirus bearing the cDNA coding for the rat muscarinic acetylcholine (ACh) receptor subtype m3, ionic flux across the membrane in response to the application of ACh was examin