Výsledky vyhledávání - "L. S. Mainwaring"

Rosiglitazone induces the unfolded protein response, but has no significant effect on cell viability, in monocytic and vascular smooth muscle cells

Autor: Richard Webb, Roger H. K. Morris, Aled Roberts, E. Adam, J. Caddy, SA Isa, L. S. Mainwaring, Derek Lang, A. W. Thomas

Publikováno v: Biochemical and Biophysical Research Communications. 400:689-695

Given the safety concerns expressed over negative cardiovascular outcomes resulting from the clinical use of rosiglitazone, and the view that rosiglitazone exerts PPARγ-independent effects alongside its insulin-sensitising PPARγ-dependent effects,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3d0a85191f7ea070bb5029b5273dce
https://doi.org/10.1016/j.bbrc.2010.08.129

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The non-genomic effects of high doses of Rosiglitazone on cell growth and apoptosis in cultured monocytic cells

Autor: SA Isa, Richard Webb, A. W. Thomas, L. S. Mainwaring

Publikováno v: Bayero Journal of Pure and Applied Sciences; Vol 2, No 2 (2009); 1-7

Peroxisome Proliferator-Activated Receptor gamma (PPARγ) is a ligand-activated transcription factor which belongs to the nuclear hormone superfamily and has multiple pharmacological ligands called Thiazolidinediones (TZDs). TZDs are a class of drugs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04cd51bebf61e82fccb4c3c852caeb56
https://doi.org/10.4314/bajopas.v2i2.63716

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