Zobrazeno 1 - 10
of 19
pro vyhledávání: '"L. S. MELVIN"'
Autor:
A. Nannipieri, Munkang Choi, P. Asenov, D. Sherlekar, Jaehyun Lee, L. S. Melvin, L. Sponton, Binjie Cheng, S. Jones, X-W. Lin, Victor Moroz, Jacky Huang
Publikováno v:
2020 IEEE International Electron Devices Meeting (IEDM).
Instead of marching from one crisply defined technology node to the next with an uncertain timeline, industry is transitioning toward annual technology updates driven by a schedule, but with an uncertain transistor density increase. Full node updates
Autor:
E. G. ANDREWS, G. W. ANTOGNOLI, R. BRESLOW, M. P. CARTA, T. J. CARTY, R. J. CHAMBERS, J. B. CHENG, V. L. COHAN, J. L. COLLINS, D. B. DAMON, J. DELEHUNT, J. F. EGGLER, J. D. ESKRA, K. W. FREIERT, W. A. HADA, A. MARFAT, H. MASAMUNE, L. S. MELVIN, C. J. MULARSKI, B. A. NACLERIO, et al. et al.
Publikováno v:
ChemInform. 26
Autor:
Raphael Mechoulam, P. J. Little, Billy R. Martin, W. R. Prescott, S. J. Ward, L S Melvin, M R Johnson, Brian F. Thomas, D R Compton, Raj K. Razdan
Publikováno v:
Pharmacology Biochemistry and Behavior. 40:471-478
Numerous cannabinoids have been synthesized that are extremely potent in all of the behavioral assays conducted in our laboratory. An important feature in increasing potency has been the substitution of a dimethylheptyl (DMH) side chain for the penty
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 25(2)
Tenidap is a new antirheumatic drug currently undergoing clinical evaluation. It inhibits production and activity of cytokines in vivo and causes significant reductions in plasma markers of disease activity in rheumatoid arthritis. After the oral adm
Publikováno v:
Drug design and discovery. 13(2)
Previous studies of the structure-activity relationships (SAR) for binding of a series of AC-bicyclic cannabinoid structures to the cannabinoid receptors in rat brain (believed to comprise the CB1 subtype) demonstrated the importance of the A-ring ar
Publikováno v:
Molecular pharmacology. 44(5)
Cannabimimetic compounds, such as delta 9-tetrahydrocannabinol (delta 9-THC), evoke analgesia in addition to other behavioral responses in humans and animals. The cannabinoid receptor mediating this response has been characterized by its ability to b
Cannabinoid structure-activity relationships: correlation of receptor binding and in vivo activities
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 265(1)
Although a receptor exists for cannabinoid drugs, it is uncertain which pharmacological actions this receptor mediates. This structure-activity relationship investigation was initiated to determine which effects might correspond to binding affinity f
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 260(1)
Opening of the pyran ring of delta 9-tetrahydrocannabinol (THC) produces cannabidiol, a bicyclic cannabinoid devoid of many pharmacological properties produced by delta 8-THC or delta 9-THC. Interestingly, the bicyclic compound CP-47,497 (VI) has bee
Publikováno v:
NIDA research monograph. 105
Publikováno v:
NIDA research monograph. 96