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Engineering adoptive T cell therapy to co-opt Fas ligand-mediated death signaling in ovarian cancer enhances therapeutic efficacy

Autor: Philip D Greenberg, Kristin G Anderson, Shannon K Oda, Breanna M Bates, Madison G Burnett, Magdalia Rodgers Suarez, Susan L Ruskin

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)

Background In the USA, more than 50% of patients with ovarian cancer die within 5 years of diagnosis, highlighting the need for therapeutic innovations. Mesothelin (MSLN) is a candidate immunotherapy target; it is overexpressed by ovarian tumors and

Externí odkaz: https://doaj.org/article/16c482feb17b4df89dbc5b52b72fb431

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ДЕКОМПОЗИЦІЙНИЙ МЕТОД ВИРІШЕННЯ ЗАВДАНЬ АНАЛІЗУ МАРКОВСЬКИХ СИСТЕМ ВИСОКОЇ РОЗМІРНОСТІ

Autor: L. Ruskin, O. Sira, Roman Korsun

Publikováno v: Системи управління, навігації та зв’язку. Збірник наукових праць. 2:90-94

Предметом вивчення статті є декомпозиційна обчислювальна процедура, яка використовує метод фазового укрупнення станів системи. Мета �

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::89930fab585b472374e6753ab3a0ad47
https://doi.org/10.26906/sunz.2020.2.090

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Engineering adoptive T cell therapy to co-opt Fas ligand-mediated death signaling in ovarian cancer enhances therapeutic efficacy

Autor: Philip D. Greenberg, Shannon K. Oda, Breanna M. Bates, Susan L. Ruskin, Kristin G. Anderson, Madison G. Burnett, Magdalia Rodgers Suarez

BackgroundIn the U.S., more than 50% of ovarian cancer patients die within 5 years of diagnosis, highlighting the need for innovations such as engineered T cell therapies. Mesothelin (Msln) is an attractive immunotherapy target for this cancer, as it

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::794c480b791954a026fe52e6f7d6fbda
https://doi.org/10.1101/2021.07.30.454539

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Abstract 3608: Triple checkpoint blockade, but not anti-PD1 alone, enhances the efficacy of engineered adoptive T cell therapy in advanced ovarian cancer

Autor: Kristin G. Anderson, Yapeng Su, Madison G. Burnett, Breanna M. Bates, Magdalia L. Rodgers Suarez, Susan L. Ruskin, Aesha Vakil, Valentin Voillet, Raphael Gottardo, Philip Greenberg

Publikováno v: Cancer Research. 82:3608-3608

Background: Less than half of ovarian cancer patients survive five years after diagnosis. This rate has changed little in the last 30 years, highlighting the need for novel therapies. A promising new strategy with the potential to control tumor growt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::03aaff6eb667e3147872325e0bb0c71e
https://doi.org/10.1158/1538-7445.am2022-3608

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Engineering adoptive T cell therapy to co-opt Fas ligand-mediated death signaling in ovarian cancer enhances therapeutic efficacy

Autor: Kristin G Anderson, Shannon K Oda, Breanna M Bates, Madison G Burnett, Magdalia Rodgers Suarez, Susan L Ruskin, Philip D Greenberg

Publikováno v: Journal for ImmunoTherapy of Cancer. 10:e003959

BackgroundIn the USA, more than 50% of patients with ovarian cancer die within 5 years of diagnosis, highlighting the need for therapeutic innovations. Mesothelin (MSLN) is a candidate immunotherapy target; it is overexpressed by ovarian tumors and c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16389ed3e23693bb39eb82dd4b253c25
https://doi.org/10.1136/jitc-2021-003959

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561 Triple checkpoint blockade, but not anti-PD1 alone, enhances the efficacy of engineered adoptive T cell therapy in advanced ovarian cancer

Autor: Magdalia Rodgers Suarez, Raphael Gottardo, Valentin Voillet, Philip D. Greenberg, Kristin E. Anderson, Yapeng Su, Aesha Vakil, Madison G. Burnett, Susan L. Ruskin, Breanna M. Bates

Publikováno v: Journal for ImmunoTherapy of Cancer. 9:A590-A590

BackgroundOver 20,000 women are diagnosed with ovarian cancer annually, and more than half will die within 5 years. This rate has changed little in the last 20 years, highlighting the need for therapy innovation. A promising new strategy with the pot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c77a64a186fcfd176971ed6ebf09c27
https://doi.org/10.1136/jitc-2021-sitc2021.561

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The role of the coenzymes of the B complex vitamins and amino acids in muscle metabolism and balanced nutrition

Autor: Simon L. Ruskin

Publikováno v: The American journal of digestive diseases. 13

1. The system of amino acids and coenzymes of the B Complex is necessary for the formation of the respiratory enzymes on which we depend for energy and growth.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::addb97a4cc64de9563d7083ed96362c6
https://pubmed.ncbi.nlm.nih.gov/21025086

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