Zobrazeno 1 - 10
of 3 077
pro vyhledávání: '"L. Rubin"'
Autor:
Christian Merlo, Teja Thorat, Lisa J. McGarry, Christina V. Scirica, Maral DerSarkissian, Catherine Nguyen, Yuqian M. Gu, Aruna Muthukumar, Joe Healy, Jaime L. Rubin, M. Alan Brookhart
Publikováno v:
Pulmonary Therapy, Vol 10, Iss 4, Pp 483-494 (2024)
Abstract Introduction Ivacaftor (IVA) has been shown to change the trajectory of cystic fibrosis (CF) disease progression by slowing the rate of lung function decline in clinical studies. Long-term real-world data help to confirm the durability of th
Externí odkaz:
https://doaj.org/article/87a5f56fc12f4e5c98c0384be3eeadd6
Autor:
Khaled Saab, Siyi Tang, Mohamed Taha, Christopher Lee-Messer, Christopher Ré, Daniel L. Rubin
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-9 (2024)
Abstract A major barrier to deploying healthcare AI is trustworthiness. One form of trustworthiness is a model’s robustness across subgroups: while models may exhibit expert-level performance on aggregate metrics, they often rely on non-causal feat
Externí odkaz:
https://doaj.org/article/1fd90123b45c4a549e735c5d951c7690
Effect of Flooding on Water-Table Elevation and Salinity in an Abandoned Coastal Agricultural Field.
Autor:
L. Rubin, E. Victoria1 (AUTHOR), Blum, Linda K.1 (AUTHOR), Mills, Aaron L.1 (AUTHOR) amills@virginia.edu
Publikováno v:
Journal of Coastal Research. 2024, Vol. 40 Issue 4, p683-695. 13p.
Autor:
Laurel A. Habel, Stacey E. Alexeeff, Ninah Achacoso, Vignesh A. Arasu, Aimilia Gastounioti, Lawrence Gerstley, Robert J. Klein, Rhea Y. Liang, Jafi A. Lipson, Walter Mankowski, Laurie R. Margolies, Joseph H. Rothstein, Daniel L. Rubin, Li Shen, Adriana Sistig, Xiaoyu Song, Marvella A. Villaseñor, Mark Westley, Alice S. Whittemore, Martin J. Yaffe, Pei Wang, Despina Kontos, Weiva Sieh
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-9 (2023)
Abstract Background Breast density is strongly associated with breast cancer risk. Fully automated quantitative density assessment methods have recently been developed that could facilitate large-scale studies, although data on associations with long
Externí odkaz:
https://doaj.org/article/c80b8409fd6744bfba5b869ab41e08e7
Autor:
Dominique Kelly, Victoria L. Rubin
Publikováno v:
Social Media + Society, Vol 10 (2024)
Dark patterns are user interface (UI) strategies deliberately designed to influence users to perform actions or make choices that benefit online service providers. This mixed methods study examines dark patterns employed by social networking sites (S
Externí odkaz:
https://doaj.org/article/eb4ca54b2f2f4c429ef9218be542ae42
Autor:
Michelle E. Watts, Richard M. Giadone, Alban Ordureau, Kristina M. Holton, J. Wade Harper, Lee L. Rubin
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2024)
Amyotrophic lateral sclerosis (ALS) is a degenerative motor neuron (MN) disease with severely limited treatment options. Identification of effective treatments has been limited in part by the lack of predictive animal models for complex human disorde
Externí odkaz:
https://doaj.org/article/07a719891bc64b85b0e8e936ef3f5f4e
Autor:
Stephen M. Moore, James D. Quirk, Andrew W. Lassiter, Richard Laforest, Gregory D. Ayers, Cristian T. Badea, Andriy Y. Fedorov, Paul E. Kinahan, Matthew Holbrook, Peder E. Z. Larson, Renuka Sriram, Thomas L. Chenevert, Dariya Malyarenko, John Kurhanewicz, A. McGarry Houghton, Brian D. Ross, Stephen Pickup, James C. Gee, Rong Zhou, Seth T. Gammon, Henry Charles Manning, Raheleh Roudi, Heike E. Daldrup-Link, Michael T. Lewis, Daniel L. Rubin, Thomas E. Yankeelov, Kooresh I. Shoghi
Publikováno v:
Tomography, Vol 9, Iss 3, Pp 995-1009 (2023)
Preclinical imaging is a critical component in translational research with significant complexities in workflow and site differences in deployment. Importantly, the National Cancer Institute’s (NCI) precision medicine initiative emphasizes the use
Externí odkaz:
https://doaj.org/article/c03b45b43e1546d4a22efc4f2e820217
Autor:
Kimberly C. Paul, Richard C. Krolewski, Edinson Lucumi Moreno, Jack Blank, Kristina M. Holton, Tim Ahfeldt, Melissa Furlong, Yu Yu, Myles Cockburn, Laura K. Thompson, Alexander Kreymerman, Elisabeth M. Ricci-Blair, Yu Jun Li, Heer B. Patel, Richard T. Lee, Jeff Bronstein, Lee L. Rubin, Vikram Khurana, Beate Ritz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Parkinson’s disease (PD) is a complex neurodegenerative disease with etiology rooted in genetic vulnerability and environmental factors. Here we combine quantitative epidemiologic study of pesticide exposures and PD with toxicity screening
Externí odkaz:
https://doaj.org/article/47501552806549668543baa91639d880
Autor:
Emel Alkim, Heidi Dowst, Julie DiCarlo, Lacey E. Dobrolecki, Anadulce Hernández-Herrera, David A. Hormuth, Yuxing Liao, Apollo McOwiti, Robia Pautler, Mothaffar Rimawi, Ashley Roark, Ramakrishnan Rajaram Srinivasan, Jack Virostko, Bing Zhang, Fei Zheng, Daniel L. Rubin, Thomas E. Yankeelov, Michael T. Lewis
Publikováno v:
Tomography, Vol 9, Iss 2, Pp 810-828 (2023)
Co-clinical trials are the concurrent or sequential evaluation of therapeutics in both patients clinically and patient-derived xenografts (PDX) pre-clinically, in a manner designed to match the pharmacokinetics and pharmacodynamics of the agent(s) us
Externí odkaz:
https://doaj.org/article/e0d87f8b7a8e4f92951123a867d724ef
Autor:
Francesca Rapino, Ted Natoli, Francesco Limone, Erin O’Connor, Jack Blank, Matthew Tegtmeyer, William Chen, Erika Norabuena, Juhi Narula, Dane Hazelbaker, Gabriella Angelini, Lindy Barrett, Alison O’Neil, Ursula K. Beattie, Jessica M. Thanos, Heather de Rivera, Steven D. Sheridan, Roy H. Perlis, Steven A. McCarroll, Beth Stevens, Aravind Subramanian, Ralda Nehme, Lee L. Rubin
Publikováno v:
Stem Cell Reports, Vol 18, Iss 1, Pp 237-253 (2023)
Summary: In the brain, the complement system plays a crucial role in the immune response and in synaptic elimination during normal development and disease. Here, we sought to identify pathways that modulate the production of complement component 4 (C
Externí odkaz:
https://doaj.org/article/660be2f0da164413bfeab8d8ecac144d