T006 Increase in S100B and LDH as early outcome predictors for non-responsiveness to anti-PD1 monotherapy in advanced melanoma

Autor: L. Rozeman, R. Mortiz, S. Wilgenhof, H. Van Thienen, J. Haanen, M. Van Den Heuvel, C. Blank, H. Van Rossum

Publikováno v: Clinica Chimica Acta. 530:S51

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2cf228b050fb3d6cce85e9dca0e7fb0a
https://doi.org/10.1016/j.cca.2022.04.243

THU0024 Treatment with immune checkpoint inhibitors and the break of b-cell tolerance to autoantigens

Autor: E.H. Kapiteijn, Els M. E. Verdegaal, Annette Grummels, Jaap A. Bakker, Twj Huizinga, L. Rozeman, Rem Toes, E.C. de Moel, J.B.A.G. Haanen, D. van der Woude

Publikováno v: THURSDAY, 14 JUNE 2018.

Background The field of autoimmunity may benefit from the knowledge gained by studying immune checkpoint inhibitors. These agents, which have proven remarkably successful in treating various types of cancer, inhibit negative costimulatory signals to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a6b295e2272f72bc6a26162b94fc3442
https://doi.org/10.1136/annrheumdis-2018-eular.3017

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Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

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C, Manning B, Woelcke J, Tan M, Manfreda S, Ponce T, Kam J, Saini R, Banker K, Salko T, Nandy P, Tawfik R, O’Neil G, Manne S, Jirvankar P, Lal S, Nema D, Jose J, Collins R, Bailey K, Blumenthal R, Colhoun H, Gersh B, Abreu M, Actis MV, Aiub J, Aiub F, Albisu J, Alvarisqueta A, Avalos V, Barreto M, Berli MA, Blumberg C, Bocanera M, Botta C, Bowen L, Budassi N, Buhlman S, Westberg JC, Carabajal T, Caruso G, Casala J, Cendali G, Coloma G, Berra FC, Cuneo C, Degennaro N, Dellasa M, Diaz M, Dos Santos P, Espinosa V, Facello A, Facello M, Farias E, Fernandez AA, Ferrari V, Pacora FF, Flores GS, Franco M, Gabito A, Viola HG, Garcia F, Garcia Duran R, Garcia Pinna J, Glenny J, Godoy Sanchez M, Grosse A, Guzman P, Hasbani E, Hominal M, Ibañez J, Jure H, Jure D, Vico ML, Liniado G, Luciardi H, Luquez H, Maehara G, Maffei L, Majul C, Mallagray M, Marinaro S, Martinez J, Massaccesi R, De Los Milagros Had M, Azize GM, Montana O, Montenegro E, Morell Y, Muntaner J, Navarrete S, Olmedo M, Paganini M, 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Publikováno v: Paediatrics Publications
New England journal of medicine, 377(12), 1119-1131. Massachussetts Medical Society

Background: Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved. Methods: We conduc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9352d7ff99dee51001e96d9b05970fb
https://doi.org/10.1056/nejmoa1707914