Zobrazeno 1 - 10
of 570
pro vyhledávání: '"L. Ralph"'
Autor:
M Elise Lauterbur, Maria Izabel A Cavassim, Ariella L Gladstein, Graham Gower, Nathaniel S Pope, Georgia Tsambos, Jeffrey Adrion, Saurabh Belsare, Arjun Biddanda, Victoria Caudill, Jean Cury, Ignacio Echevarria, Benjamin C Haller, Ahmed R Hasan, Xin Huang, Leonardo Nicola Martin Iasi, Ekaterina Noskova, Jana Obsteter, Vitor Antonio Correa Pavinato, Alice Pearson, David Peede, Manolo F Perez, Murillo F Rodrigues, Chris CR Smith, Jeffrey P Spence, Anastasia Teterina, Silas Tittes, Per Unneberg, Juan Manuel Vazquez, Ryan K Waples, Anthony Wilder Wohns, Yan Wong, Franz Baumdicker, Reed A Cartwright, Gregor Gorjanc, Ryan N Gutenkunst, Jerome Kelleher, Andrew D Kern, Aaron P Ragsdale, Peter L Ralph, Daniel R Schrider, Ilan Gronau
Publikováno v:
eLife, Vol 12 (2023)
Simulation is a key tool in population genetics for both methods development and empirical research, but producing simulations that recapitulate the main features of genomic datasets remains a major obstacle. Today, more realistic simulations are pos
Externí odkaz:
https://doaj.org/article/ed75e3569fbf474782ef3b9546fe2394
Autor:
Ting Yang, Chengcheng Song, Donna L. Ralph, Portia Andrews, Matthew A. Sparks, Beverly H. Koller, Alicia A. McDonough, Thomas M. Coffman
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 19 (2022)
Background A beneficial role for prostanoids in hypertension is suggested by clinical studies showing nonsteroidal anti‐inflammatory drugs, which block the production of all prostanoids, cause sodium retention and exacerbate hypertension. Among pro
Externí odkaz:
https://doaj.org/article/1e745101eca4475590b2c265fe58e7d5
Publikováno v:
Quality Advancement in Nursing Education, Vol 8, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/413052055d0a454ab3ca554d9956c7c0
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3813-3824 (2019)
Since the autosomal genome is shared between the sexes, sex-specific fitness optima present an evolutionary challenge. While sexually antagonistic selection might favor different alleles within females and males, segregation randomly reassorts allele
Externí odkaz:
https://doaj.org/article/ee68887b530a42d28ba4669383ee3206
Publikováno v:
eLife, Vol 9 (2020)
Most organisms are more closely related to nearby than distant members of their species, creating spatial autocorrelations in genetic data. This allows us to predict the location of origin of a genetic sample by comparing it to a set of samples of kn
Externí odkaz:
https://doaj.org/article/c8f96fbabc284438b9d14bd1d30b6878
Autor:
Jeffrey R Adrion, Christopher B Cole, Noah Dukler, Jared G Galloway, Ariella L Gladstein, Graham Gower, Christopher C Kyriazis, Aaron P Ragsdale, Georgia Tsambos, Franz Baumdicker, Jedidiah Carlson, Reed A Cartwright, Arun Durvasula, Ilan Gronau, Bernard Y Kim, Patrick McKenzie, Philipp W Messer, Ekaterina Noskova, Diego Ortega-Del Vecchyo, Fernando Racimo, Travis J Struck, Simon Gravel, Ryan N Gutenkunst, Kirk E Lohmueller, Peter L Ralph, Daniel R Schrider, Adam Siepel, Jerome Kelleher, Andrew D Kern
Publikováno v:
eLife, Vol 9 (2020)
The explosion in population genomic data demands ever more complex modes of analysis, and increasingly, these analyses depend on sophisticated simulations. Recent advances in population genetic simulation have made it possible to simulate large and c
Externí odkaz:
https://doaj.org/article/3524c850e8cf4035a0c097b7202a542b
Autor:
Iuri C. Valadão, Ana Carolina L. Ralph, François Bordeleau, Luciana M. Dzik, Karen S.C. Borbely, Murilo V. Geraldo, Cynthia A. Reinhart-King, Vanessa M. Freitas
Publikováno v:
PeerJ, Vol 8, p e9153 (2020)
Breast cancer is a highly frequent and lethal malignancy which metastasis and relapse frequently associates with the existence of breast cancer stem cells (CSCs). CSCs are undifferentiated, aggressive and highly resistant to therapy, with traits modu
Externí odkaz:
https://doaj.org/article/1e0ac16b7741462d92bda7bffd6291cb
Autor:
Frederick A Matsen, Peter L Ralph
Publikováno v:
Journal of Computational Biology. 29:802-824
Although the rates at which positions in the genome mutate are known to depend not only on the nucleotide to be mutated, but also on neighboring nucleotides, it remains challenging to do phylogenetic inference using models of context-dependent mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a97d1685f13ce6ff06212af33ec243b1
https://doi.org/10.1089/cmb.2021.0644
https://doi.org/10.1089/cmb.2021.0644
Autor:
Sean Stankowski, Madeline A Chase, Allison M Fuiten, Murillo F Rodrigues, Peter L Ralph, Matthew A Streisfeld
Publikováno v:
PLoS Biology, Vol 17, Iss 7, p e3000391 (2019)
Speciation genomic studies aim to interpret patterns of genome-wide variation in light of the processes that give rise to new species. However, interpreting the genomic "landscape" of speciation is difficult, because many evolutionary processes can i
Externí odkaz:
https://doaj.org/article/69f877714acc4c49aa6616b2df8a3f76
Autor:
Piercy, L. Ralph (AUTHOR), Levy, Howard B. (AUTHOR)
Publikováno v:
CPA Journal. Dec2021, Vol. 91 Issue 12, p54-57. 4p. 2 Charts.