Zobrazeno 1 - 10
of 265
pro vyhledávání: '"L. Radice"'
Publikováno v:
Cell Reports, Vol 21, Iss 8, Pp 2236-2250 (2017)
Many adult stem cells display prolonged quiescence, promoted by cues from their niche. Upon tissue damage, a coordinated transition to the activated state is required because non-physiological breaks in quiescence often lead to stem cell depletion an
Externí odkaz:
https://doaj.org/article/fd673d222e86401aa88ebc9e1983590d
The cardiomyocyte phenotypic switch from a proliferative to terminally differentiated state results in the loss of regenerative potential of the mammalian heart shortly after birth. Yet, the molecular mechanisms that regulate this critical developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1704ada5cd69e3f143f67d0df5c4dc5e
https://hdl.handle.net/11541.2/32645
https://hdl.handle.net/11541.2/32645
Autor:
Keeley L. Mui, Yong Ho Bae, Lin Gao, Shu-Lin Liu, Tina Xu, Glenn L. Radice, Christopher S. Chen, Richard K. Assoian
Publikováno v:
Cell Reports, Vol 10, Iss 9, Pp 1477-1486 (2015)
In contrast to the accepted pro-proliferative effect of cell-matrix adhesion, the proliferative effect of cadherin-mediated cell-cell adhesion remains unresolved. Here, we studied the effect of N-cadherin on cell proliferation in the vasculature. We
Externí odkaz:
https://doaj.org/article/dbf50ae3f4f74ad6933a55a8a67f774b
Autor:
Jifen Li, Glenn L. Radice
Publikováno v:
Dermatology Research and Practice, Vol 2010 (2010)
Adherens junctions and desmosomes are intercellular adhesive junctions and essential for the morphogenesis, differentiation, and maintenance of tissues that are subjected to high mechanical stress, including heart and skin. The different junction com
Externí odkaz:
https://doaj.org/article/aad5970e0b5f447f924fc5699306a629
Publikováno v:
Cell Reports, Vol 21, Iss 8, Pp 2236-2250 (2017)
Many adult stem cells display prolonged quiescence, promoted by cues from their niche. Upon tissue damage, a coordinated transition to the activated state is required because non-physiological breaks in quiescence often lead to stem cell depletion an
Autor:
Glenn L. Radice, A. Sue Menko, Caitlin Bowen, Caitlin M. Logan, Michael L. Robinson, Suren Rajakaruna
Publikováno v:
Developmental Biology. 428:118-134
Tissue development and regeneration involve high-ordered morphogenetic processes that are governed by elements of the cytoskeleton in conjunction with cell adhesion molecules. Such processes are particularly important in the lens whose structure dict
Autor:
John J. Schwarz, Mingfu Wu, Leo Q. Wan, Glenn L. Radice, Lianjie Miao, Peter A. Vincent, Hongbo Xin, Weimin Zhong, Zhen-Chuan Fan, Jingjing Li, Jian Li, Joseph E. Mazurkiewicz, Harold A. Singer, Yangyang Lu, Margarida Barroso, David Shieh, Guoying Huang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The formation of ridge-like trabeculae from the myocardium is central to heart formation, as it allows for the increase in muscle mass before the formation of coronary circulation. We found that cardiomyocytes display spatiotemporal orie
Akademický článek
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Publikováno v:
Circulation Research. 123
Cells sense and transduce mechanical signals through cell-cell adhesions and cell-extracellular matrix adhesions. After birth, contractile force generation and tissue stiffness increase as cardiac output increases to support the needs of the newborn
Publikováno v:
Development.
Shortly after birth, muscle cells of the mammalian heart lose their ability to divide. At the same time, the N-cadherin/catenin cell adhesion complex accumulates at the cell termini creating a specialized type of cell-cell contact called the intercal