Výsledky vyhledávání - "L. R. Velatooru"

In vitro apoptotic mechanism of a novel synthetic Quinazolinyl derivative: Induces caspase-dependent intrinsic pathway on THP-1, leukemia cell line

Autor: S.K. Arepalli, L. R. Velatooru, J. Venkateswara Rao, Sridhar Vakamullu, Banda Narsaiah, P Kavin Kennedy

Publikováno v: Chemico-biological interactions. 280

Several quinazoline derivatives have been found to possess a broad spectrum of biological activities. Previously our research group has synthesized and studied the anti-proliferative effects of N-Decyl-N-(2-Methyl-4-Quinazolinyl) Amine (DMQA). The cu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::221135490a145cc601914887db2fc718
https://pubmed.ncbi.nlm.nih.gov/29225136

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Synthesis of novel fluoro 1,2,3-triazole tagged amino bis(benzothiazole) derivatives, their antimicrobial and anticancer activity

Autor: Y. Khageswara Rao, J. Venkateswara Rao, Umesh B. Kosurkar, Rajesh Pamanji, Ravindra M. Kumbhare, L. R. Velatooru, Tulshiram L. Dadmal, K. Appalanaidu

Publikováno v: Medicinal Chemistry Research. 23:4404-4413

A new series of fluoro 1,2,3-triazole tagged amino bis (benzothiazole) derivatives 8, 9 were prepared starting from 2-amino benzothiazole in four steps via amination, cyclization, alkylation followed by reaction with various azides under sharpless co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ed29b73c54936c9d2f1d46209d6cd2c5
https://doi.org/10.1007/s00044-014-1006-0

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Synthesis, characterization, and anticancer studies of S and N alkyl piperazine-substituted positional isomers of 1,2,4-triazole derivatives

Autor: M. S. R. Murty, Rajesh Pamanji, Janapala Venkateswara Rao, Rayudu Venkateswara Rao, Kesur R. Ram, B. Ramalingeswara Rao, L. R. Velatooru, Mohana Rao Katiki

Publikováno v: Medicinal Chemistry Research. 23:1661-1671

A series of 3-[3-[4-(substituted)-1-cyclicamine]propyl]thio-5-substituted[1,2,4]triazoles (8a–m) and 2-[3-[4-(substituted)-1-cyclicamine]propyl]-5-(substituted)-2,4-dihydro-3H[1,2,4]triazole-3-thiones (9a–h) were synthesized with good yields star

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02eae2c73d650728459d67f0f872adee
https://doi.org/10.1007/s00044-013-0757-3

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Synthesis of New S-alkylated-3-mercapto-1,2,4-triazole Derivatives Bearing Cyclic Amine Moiety as Potent Anticancer Agents

Autor: Rayudu Venkateswara Rao, M. S. R. Murty, Janapala Venkateswara Rao, L. R. Velatooru, J. S. Yadav, Kesur R. Ram

Publikováno v: Letters in Drug Design & Discovery. 9:276-281

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee39a5e9dcbf29ecf0f14f9b127df184
https://doi.org/10.2174/157018012799129882

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GdCl3 promoted synthesis of novel pyrimidine fused indazole derivatives and their anticancer activity

Autor: B. P. V. Lingaiah, S. Gururaj, Balasubramanian Sridhar, T. Parthasarathy, Rajesh Pamanji, T. Yakaiah, L. R. Velatooru, Banda Narsaiah, C. Kurumurthy, J. Venkateswara Rao

Publikováno v: Medicinal Chemistry Research. 21:4261-4273

The three component Grieco condensation of indazoles, aliphatic/aromatic aldehydes, and electron rich olefins in the presence of GdCl3 resulted in a novel pyrimidine fused indazoles in single pot under mild conditions. Representative examples were sc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6aafa908c4f7e2f6e1b77e997b2ea45c
https://doi.org/10.1007/s00044-011-9962-0

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Synthesis of novel alkyltriazole tagged pyrido[2,3-d]pyrimidine derivatives and their anticancer activity

Autor: P. Sambasiva Rao, Banda Narsaiah, J. Venkateswara Rao, L. R. Velatooru, C. Kurumurthy, Rajesh Pamanji, B. Veera swamy, P. Shanthan Rao, G. Santhosh Kumar

Publikováno v: European Journal of Medicinal Chemistry. 46:3462-3468

A series of novel alkyltriazole tagged pyrido[2,3-d]pyrimidine derivatives 5 and 6 was prepared starting from 2,3-active functional pyridine 1via cyclization, propargylation followed by reaction with alkyl or perfluoroalkyl azides under Sharpless con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8293c5847ba5259966999647b0a5f8a
https://doi.org/10.1016/j.ejmech.2011.05.011

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ChemInform Abstract: Synthesis of Novel Alkyltriazole Tagged Pyrido[2,3-d]pyrimidine Derivatives and Their Anticancer Activity

Autor: L. R. Velatooru, Rajesh Pamanji, C. Kurumurthy, B. Veera swamy, P. Sambasiva Rao, Banda Narsaiah, G. Santhosh Kumar, J. Venkateswara Rao, P. Shanthan Rao

Publikováno v: ChemInform. 42

Pyridopyrimidines (VIII) and (IX) are obtained from the 2,3-active functional pyridine (I) via cyclization, propargylation and reaction with alkyl or perfluoroalkylazides under Sharpless conditions.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b9eaf9c983f2db802e7882235d7ed1e
https://doi.org/10.1002/chin.201144159

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