Zobrazeno 1 - 10 of 13 pro vyhledávání: '"L. R. Meyerson"'
1
Use of ex vivo magnetic resonance imaging to detect onset of vigabatrin-induced intramyelinic edema in canine brain
Autor: B. L. Hershey, L. R. Meyerson, John P. Gibson, John T. Yarrington, Neil M. Sussman, Robert G. Peyster, William E Heydorn
Publikováno v: Epilepsia. 36(1)
Vigabatrin (VGB) causes intramyelinic edema (microvacuolation) in brain of dogs and rodent, which has encouraged development of noninvasive methods to monitor for this effect during clinical trials. We report the qualitative ex vivo magnetic resonanc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a30cb395e6bb72455e53c0c18a65737
https://pubmed.ncbi.nlm.nih.gov/8001516
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2
2-Nitroimipramine: a photoaffinity probe for the serotonin uptake/tricyclic binding site complex
Autor: D. I. Schuster, R. B. Murphy, L. P. Wennogle, R. A. Ashton, L. R. Meyerson
Publikováno v: The EMBO Journal. 4:971-977
[3H]2-Nitroimipramine ([3H]2-NI), a compound with high affinity for the serotonin uptake system, is shown to be an effective photoaffinity probe which incorporates covalently into membrane homogenates prepared from human platelets, as well as rat bra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf8264d10f2f95eee1ba39ed6e14b245
https://doi.org/10.1002/j.1460-2075.1985.tb03726.x
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3
Synthesis and analgesic activity of some 5-(4-hydroxyphenyl)-2-azabicyclo[3.2.1]octanes
Autor: V. B. Anderson, L. R. Meyerson, J. C. Wilker, Helen H. Ong, T. C. Spaulding
Publikováno v: Journal of Medicinal Chemistry. 23:726-729
A representative series of 5-(4-hydroxyphenyl)-2-azabicyclo[3.2.1]octanes was synthesized and evaluated in vitro, as well as in vivo, as potential analgetic agents. In general, moderate to good activity (19 twice as active as morphine) was observed i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::877b8d5fb65be411a166e232192050b3
https://doi.org/10.1021/jm00181a005
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4
5-Aryl-3-azabicyclo[3.2.0]heptan-6-one ketals, compounds with morphine-like analgesic activity
Autor: T C, McKenzie, J W, Epstein, W J, Fanshawe, J S, Dixon, A C, Osterberg, L P, Wennogle, B A, Regan, M S, Abel, L R, Meyerson
Publikováno v: Journal of medicinal chemistry. 27(5)
A series of 5-aryl-3-azabicyclo[3.2.0] heptan -6-one ketals 6 were synthesized by hydride reduction of 1-aryl-4, 4-dimethoxy-1,2- cyclobutanedicarboximides 5. Imides 5 were obtained as the sole, regioselective products of the [2 + 2] photocycloadditi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b663f4920a9b9b23c76c315640448673
https://pubmed.ncbi.nlm.nih.gov/6325691
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8
ChemInform Abstract: SYNTHESIS AND ANALGESIC ACTIVITY OF SOME 5-(4-HYDROXYPHENYL)-2-AZABICYCLO(3.2.1)OCTANES
Autor: T. C. Spaulding, J. C. Wilker, V. B. Anderson, L. R. Meyerson, Helen H. Ong
Publikováno v: Chemischer Informationsdienst. 11
A representative series of 5-(4-hydroxyphenyl)-2-azabicyclo[3.2.1]octanes was synthesized and evaluated in vitro, as well as in vivo, as potential analgetic agents. In general, moderate to good activity (19 twice as active as morphine) was observed i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8c9369e943ae3eac7ee6eeab1e60ed27
https://doi.org/10.1002/chin.198049219
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