Zobrazeno 1 - 5
of 5
pro vyhledávání: '"L. R. Mantegna"'
Autor:
R. Goodman, L. R. Mantegna, C. L. McAIlister, E. Bruin, R. L. Dowling, H. George, W. Feeser, B. Freimark, M. Lischwe, S. Pick, R. R. Harris, J. S. Kerr
Publikováno v:
Mediators of Inflammation, Vol 2, Iss 1, Pp 33-39 (1993)
The carrageenan pleurisy model, which is characterized by cellular influx and oedema, has been used to examine the effects of anti-inflammatory compounds such as naproxen. Interleukin-1α and β (IL-1) are known to be pro-inflammatory mediators, and
Externí odkaz:
https://doaj.org/article/c0fa3ac0cbd14908a8ab91e60fb102ca
Autor:
S. Pick, B. Freimark, E. M. Bruin, C. L. McAIlister, H. George, R. Goodman, L. R. Mantegna, R. L. Dowling, Janet S. Kerr, R. R. Harris, W. Feeser, M. Lischwe
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2, Iss 1, Pp 33-39 (1993)
Mediators of Inflammation, Vol 2, Iss 1, Pp 33-39 (1993)
The carrageenan pleurisy model, which is characterized by cellular influx and oedema, has been used to examine the effects of anti-inflammatory compounds such as naproxen. Interleukin-1alpha and beta (IL-1) are known to be pro-inflammatory mediators,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ed961487502a2959ba5bcbbc3d0a2a
http://europepmc.org/articles/PMC2365377
http://europepmc.org/articles/PMC2365377
ChemInform Abstract: 2′-Substituted Chalcone Derivatives as Inhibitors of Interleukin-1 Biosynthesis
Autor:
Janet S. Kerr, Sherrill Nurnberg, P. K. Welch, L. R. Mantegna, Robin Goodman, Robert Newton, David G Jones, Maryanne B. Covington, Candice McAllister, Douglas Guy Batt
Publikováno v:
ChemInform. 25
A series of 2'-substituted chalcone derivatives has been found to show potent inhibition of the production of IL-1 beta from human peripheral blood monocytes stimulated with lipopolysaccharide (LPS), with IC50 values in the 0.2-5.0-microM range. Some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4df4bc06f6e0f3005e2ddddf6b554db
https://doi.org/10.1002/chin.199410144
https://doi.org/10.1002/chin.199410144
Autor:
S W, Wright, R R, Harris, J S, Kerr, A M, Green, D J, Pinto, E M, Bruin, R J, Collins, R L, Dorow, L R, Mantegna, S R, Sherk
Publikováno v:
Journal of Medicinal Chemistry. 35:4061-4068
Vinylogous hydroxamic acids (3-(N-hydroxy-N-alkylamino)-2-propen-1-ones, VHA) were prepared as antiinflammatory agents. The synthesis, chemical properties, and in vitro biological activities of these relatively unexplored compounds are described. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1610f027838fd26641fc716db57f498d
https://doi.org/10.1021/jm00100a011
https://doi.org/10.1021/jm00100a011
Autor:
Maryanne B. Covington, Janet S. Kerr, Candice McAllister, P. K. Welch, Douglas Guy Batt, Robert Newton, David G Jones, Sherrill Nurnberg, L. R. Mantegna, Robin Goodman
Publikováno v:
Journal of medicinal chemistry. 36(10)
A series of 2'-substituted chalcone derivatives has been found to show potent inhibition of the production of IL-1 beta from human peripheral blood monocytes stimulated with lipopolysaccharide (LPS), with IC50 values in the 0.2-5.0-microM range. Some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f125b733f5559b861eef8375df10e993
https://pubmed.ncbi.nlm.nih.gov/8496911
https://pubmed.ncbi.nlm.nih.gov/8496911