Zobrazeno 1 - 10
of 23
pro vyhledávání: '"L. R. Ellingsworth"'
Publikováno v:
The Journal of Immunology. 145:2514-2519
We investigated potential mechanisms by which lymphocytes infiltrating rheumatoid synovium become immunosuppressed. In 20 of 22 synovial fluids and 12 of 13 synovial tissue culture supernatants, no IL-1 bioactivity could be detected in the thymocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::309ffe1a42e26cbeea336c1666b3cf92
https://doi.org/10.4049/jimmunol.145.8.2514
https://doi.org/10.4049/jimmunol.145.8.2514
Publikováno v:
Blood. 75:626-632
We examined the effect of transforming growth factor-beta (TGF-beta) alone and in combinations with other factors on the growth and differentiation of the human promyelocytic cell line HL60 and the human monoblastic cell line U937. Treatment with TGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d87c0d3c7a298aa6109fd349d82a5d8
https://doi.org/10.1182/blood.v75.3.626.bloodjournal753626
https://doi.org/10.1182/blood.v75.3.626.bloodjournal753626
Publikováno v:
Experimental hematology. 20(8)
Transforming growth factor beta 1 (TGF-beta 1) has been shown to inhibit the development of most early hemopoietic progenitors in vitro. The present series of in vivo experiments show that TGF-beta 1 can simultaneously augment and suppress distinct c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81b27efd7a5961fec7151e648fbbcad8
https://pubmed.ncbi.nlm.nih.gov/1505639
https://pubmed.ncbi.nlm.nih.gov/1505639
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 145(8)
We investigated potential mechanisms by which lymphocytes infiltrating rheumatoid synovium become immunosuppressed. In 20 of 22 synovial fluids and 12 of 13 synovial tissue culture supernatants, no IL-1 bioactivity could be detected in the thymocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::22226b1a08393d5376967863828bbf01
https://pubmed.ncbi.nlm.nih.gov/2212650
https://pubmed.ncbi.nlm.nih.gov/2212650
Autor:
U I, Heine, S M, Wahl, E F, Munoz, J B, Allen, L R, Ellingsworth, K C, Flanders, A B, Roberts, M B, Sporn
Publikováno v:
Archiv fur Geschwulstforschung. 60(4)
We report here that extracellular TGF-beta 1 is associated exclusively with microfibrils of elastin which are present in the extracellular matrix of the inflamed articular joint of the rat. Inflammation was initiated by bacterial cell walls localized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4424d285e2e38f3e98c08fe6003c2b00
https://pubmed.ncbi.nlm.nih.gov/2167651
https://pubmed.ncbi.nlm.nih.gov/2167651
Publikováno v:
American Journal of Obstetrics and Gynecology. 139:932-936
Normal pregnancy serum from the rhesus monkey was found to have immunosuppressive activity. Using two-way stimulation, the mixed lymphocyte response was suppressed as much as 80%. Control serum from nonpregnant females was not suppressive. The inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc6f3192c3e34943d7b8cb0a2dce20c
https://doi.org/10.1016/0002-9378(81)90961-3
https://doi.org/10.1016/0002-9378(81)90961-3
Publikováno v:
Veterinary Immunology and Immunopathology. 5:141-149
A microtiter system was used to measure hemolytic complement levels in serum from eleven nonhuman primate species. The species studied were Macaca mulatta (rhesus macaque), Macaca radiata (bonnet macaque), Macaca nemestrina (pig-tailed macaque), Maca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284135b583a32356f0f9d8b94be4cef4
https://doi.org/10.1016/0165-2427(83)90015-6
https://doi.org/10.1016/0165-2427(83)90015-6
Autor:
Nancy L. Thompson, L R Ellingsworth, Anita B. Roberts, J M Smith, Michael B. Sporn, Kathleen C. Flanders
Publikováno v:
The Journal of Cell Biology
We have used immunohistochemical techniques to detect transforming growth factor-beta 1 (TGF-beta 1) in many tissues of adult and neonatal mice. Each of two antibodies raised to the amino-terminal 30 amino acids of TGF-beta 1 selectively stained this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb079436da8af6dc1839b4cee8b05c2
https://doi.org/10.1083/jcb.108.2.661
https://doi.org/10.1083/jcb.108.2.661
Autor:
U. Heine, Kathleen C. Flanders, Michael B. Sporn, Anita B. Roberts, L R Ellingsworth, E. F. Munoz, H.-Y. P. Lam, Nancy L. Thompson
Publikováno v:
The Journal of Cell Biology
Using immunohistochemical methods, we have investigated the role of transforming growth factor-beta (TGF-beta) in the development of the mouse embryo. For detection of TGF-beta in 11-18-d-old embryos, we have used a polyclonal antibody specific for T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3589bc651edb482c5bc7d093652b12be
https://doi.org/10.1083/jcb.105.6.2861
https://doi.org/10.1083/jcb.105.6.2861
Publikováno v:
The Journal of Immunology. 142:3875-3883
The ability of stromal cells in bone marrow to support B lymphopoiesis may be partially mediated by secretion of biologically active factors. The first cytokine with lymphopoietic activity to be molecularly cloned from stromal cells, IL-7, was origin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec156f2ba101f9429b7a4b0b8cbe042f
https://doi.org/10.4049/jimmunol.142.11.3875
https://doi.org/10.4049/jimmunol.142.11.3875