Neonatal Peyer’s patch cDC activation as a pacemaker of postnatal immune maturation

Autor: N. Torow, R. Li, T. Hitch, C. Mingels, S. al Bounny, N. van Best, E.-L. Stange, A. Benabid, L. Rüttger, M. Gadermayr, S. Runge, N. Treichel, D. Merhof, S. Rosshart, N. Jehmlich, M. von Bergen, F. Heymann, T. Clavel, F. Tacke, H. Lelouard, I. Costa, M. W. Hornef

Publikováno v: Cold Spring Harbor : Cold Spring Harbor Laboratory, bioRxiv : the preprint server for biology 1-41 (2022). doi:10.1101/2022.03.03.482839

Marked differences exist between the mucosal immune system of the neonate and adult host. The pronounced influence of the enteric microbiota in adults suggests a causal relationship between postnatal colonization and immune maturation. However, using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12acd04ca31cb314d1c35caba02cccf9
https://doi.org/10.1101/2022.03.03.482839

Resident regulatory T cells reflect the immune history of individual lymph nodes.

Autor: Kaminski A; Institute of Molecular Medicine, RWTH Aachen University, Aachen 52074, Germany., Hager FT; Institute of Molecular Medicine, RWTH Aachen University, Aachen 52074, Germany., Kopplin L; Institute of Molecular Medicine, RWTH Aachen University, Aachen 52074, Germany., Ticconi F; Institute of Molecular Medicine, RWTH Aachen University, Aachen 52074, Germany.; Institute for Computational Genomics, RWTH Aachen University, Aachen 52074, Germany., Leufgen A; Institute of Molecular Medicine, RWTH Aachen University, Aachen 52074, Germany., Vendelova E; Würzburg Institute of Systems Immunology, Max Planck Research Group at the Julius-Maximilians-Universität Würzburg, Würzburg 97078, Germany., Rüttger L; Würzburg Institute of Systems Immunology, Max Planck Research Group at the Julius-Maximilians-Universität Würzburg, Würzburg 97078, Germany., Gasteiger G; Würzburg Institute of Systems Immunology, Max Planck Research Group at the Julius-Maximilians-Universität Würzburg, Würzburg 97078, Germany., Cerovic V; Institute of Molecular Medicine, RWTH Aachen University, Aachen 52074, Germany., Kastenmüller W; Würzburg Institute of Systems Immunology, Max Planck Research Group at the Julius-Maximilians-Universität Würzburg, Würzburg 97078, Germany., Pabst O; Institute of Molecular Medicine, RWTH Aachen University, Aachen 52074, Germany., Ugur M; Institute of Molecular Medicine, RWTH Aachen University, Aachen 52074, Germany.; Würzburg Institute of Systems Immunology, Max Planck Research Group at the Julius-Maximilians-Universität Würzburg, Würzburg 97078, Germany.

Publikováno v: Science immunology [Sci Immunol] 2023 Nov 24; Vol. 8 (89), pp. eadj5789. Date of Electronic Publication: 2023 Nov 24.