Zobrazeno 1 - 10
of 76
pro vyhledávání: '"L. Pierri"'
Autor:
Erika M. Palmieri, Ronald Holewinski, Christopher L. McGinity, Ciro L. Pierri, Nunziata Maio, Jonathan M. Weiss, Vincenzo Tragni, Katrina M. Miranda, Tracey A. Rouault, Thorkell Andresson, David A. Wink, Daniel W. McVicar
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract M1 macrophages enter a glycolytic state when endogenous nitric oxide (NO) reprograms mitochondrial metabolism by limiting aconitase 2 and pyruvate dehydrogenase (PDH) activity. Here, we provide evidence that NO targets the PDH complex by usi
Externí odkaz:
https://doaj.org/article/c6b5815c95e344bdaaa97f1c13a3f7f7
Autor:
Alessio Menga, Marina Serra, Simona Todisco, Carla Riera‐Domingo, Ummi Ammarah, Manuel Ehling, Erika M Palmieri, Maria Antonietta Di Noia, Rosanna Gissi, Maria Favia, Ciro L Pierri, Paolo E Porporato, Alessandra Castegna, Massimiliano Mazzone
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 10, Pp 1-24 (2020)
Abstract Glutamine synthetase (GS) generates glutamine from glutamate and controls the release of inflammatory mediators. In macrophages, GS activity, driven by IL10, associates to the acquisition of M2‐like functions. Conditional deletion of GS in
Externí odkaz:
https://doaj.org/article/2172c31045fb4eb88d755d43558791aa
Autor:
Roberta Seccia, Silvia De Santis, Maria A. Di Noia, Ferdinando Palmieri, Daniela V. Miniero, Raffaele Marmo, Eleonora Paradies, Antonella Santoro, Ciro L. Pierri, Luigi Palmieri, Carlo M. T. Marobbio, Angelo Vozza
Publikováno v:
Journal of Fungi, Vol 8, Iss 8, p 795 (2022)
The yeast mitochondrial transport of GTP and GDP is mediated by Ggc1p, a member of the mitochondrial carrier family. The physiological role of Ggc1p in S. cerevisiae is probably to transport GTP into mitochondria in exchange for GDP generated in the
Externí odkaz:
https://doaj.org/article/aa35e0edf64c447faf9856528a37510b
Autor:
Anna Santarsiero, Paolo Convertini, Simona Todisco, Ciro L. Pierri, Anna De Grassi, Niamh C. Williams, Dominga Iacobazzi, Giulio De Stefano, Luke A. J. O’Neill, Vittoria Infantino
Publikováno v:
Cells, Vol 10, Iss 11, p 2962 (2021)
Macrophage stimulation by pathogen-associated molecular patterns (PAMPs) like lipopolysaccharide (LPS) or lipoteichoic acid (LTA) drives a proinflammatory phenotype and induces a metabolic reprogramming to sustain the cell’s function. Nevertheless,
Externí odkaz:
https://doaj.org/article/4c0373f557ba404185f721458bb1f4e7
Autor:
Roberta, Seccia, Silvia, De Santis, Maria A, Di Noia, Ferdinando, Palmieri, Daniela V, Miniero, Raffaele, Marmo, Eleonora, Paradies, Antonella, Santoro, Ciro L, Pierri, Luigi, Palmieri, Carlo M T, Marobbio, Angelo, Vozza
Publikováno v:
Journal of fungi (Basel, Switzerland). 8(8)
The yeast mitochondrial transport of GTP and GDP is mediated by Ggc1p, a member of the mitochondrial carrier family. The physiological role of Ggc1p in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d343be13736c8ab1797aff32ed14e11f
https://pubmed.ncbi.nlm.nih.gov/36012783
https://pubmed.ncbi.nlm.nih.gov/36012783
Autor:
Letizia, Porcelli, Roberta, Di Fonte, Ciro L, Pierri, Livia, Fucci, Concetta, Saponaro, Andrea, Armenio, Simona, Serratì, Sabino, Strippoli, Rossella, Fasano, Mariateresa, Volpicella, Rossana, Daprile, Stefania, Tommasi, Cosmo M, Ressa, Michele, Guida, Amalia, Azzariti
Publikováno v:
Pharmacological research. 182
The V600E mutation in BRAF is associated with increased phosphorylation of Erk1/2 and high sensitivity to BRAFi/MEKi combination in metastatic melanoma. In very few patients, a tandem mutation in BRAF, V600 and K601, causes a different response to BR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f91072c3d3b6d637b6d86516801dfc6b
https://pubmed.ncbi.nlm.nih.gov/35752358
https://pubmed.ncbi.nlm.nih.gov/35752358
Autor:
Valentina Cigliola, Celine Populaire, Ciro L Pierri, Samuel Deutsch, Jacques-Antoine Haefliger, João Fadista, Valeriya Lyssenko, Leif Groop, Rico Rueedi, Fabrizio Thorel, Pedro Luis Herrera, Paolo Meda
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150880 (2016)
Signalling through gap junctions contributes to control insulin secretion and, thus, blood glucose levels. Gap junctions of the insulin-producing β-cells are made of connexin 36 (Cx36), which is encoded by the GJD2 gene. Cx36-null mice feature alter
Externí odkaz:
https://doaj.org/article/235ee19e0b3f4349a307a413ec2ed52d
Akademický článek
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Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Letizia Porcelli, Roberta Di Fonte, Ciro L. Pierri, Livia Fucci, Concetta Saponaro, Andrea Armenio, Simona Serratì, Sabino Strippoli, Rossella Fasano, Mariateresa Volpicella, Rossana Daprile, Stefania Tommasi, Cosmo M. Ressa, Michele Guida, Amalia Azzariti
Publikováno v:
Pharmacological Research. 182:106323
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe13addf6cb35f104f8e653bbd9362ec
https://doi.org/10.1016/j.phrs.2022.106323
https://doi.org/10.1016/j.phrs.2022.106323