Zobrazeno 1 - 10
of 18
pro vyhledávání: '"L. Pharo"'
Publikováno v:
Journal of Clinical Oncology. 14:1913-1921
PURPOSE Based on preclinical and clinical studies that suggested amifostine may potentiate the effects of cytotoxic drugs, we conducted a phase II trial of amifostine, cisplatin, and vinblastine (ACV) in patients with metastatic non-small-cell lung c
Autor:
Marilyn Larson, Sharon M. Weber, Heidi Schalch, Dennis M. Heisey, Fushun Shi, David M. Mahvi, Joan H. Schiller, Paul M. Sondel, Thomas F. Warner, Jacek Gan, Ning-Sun Yang, L. Pharo, Hank Ja, Mark Albertini
Publikováno v:
Human gene therapy. 13(14)
The primary objective of this phase I study was to determine the safety of an autologous tumor vaccine given by intradermal injection of lethally irradiated granulocyte-macrophage colony-stimulating factor (GM-CSF) gene-transfected autologous melanom
Publikováno v:
European Journal of Cancer. 31:S230
Monthly cycles of A, 740–910 mg/m2, C, 120 mg/m2 were given on Day 1 & V, 5 mg/m2 weekly to 24 Stage IIIA/B & 23 stage IV NSCLC pts. After 2 cycles ACV, Stage III pts received 60 Gy chest RT. 67% stage III, 65% Stage IV responded to ACV. Median fol
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 90:16-23
Reduction of exogenous NADP by NADH2 in submitochondrial particles has been shown to proceed by an energy-unrelated and an energy-related transhydrogenase sequence. The latter is activated by Mg2+ and ATP, and inhibited by oligomycin and uncouplers o
Autor:
Pih-Kuei C. Huang, Richard L. Pharo
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 245:240-244
A simple procedure for the isolation and purification of the high-molecular-weight type NADH dehydrogenase from beef heart mitochondria is reported.
Publikováno v:
Archives of Biochemistry and Biophysics. 138:44-47
Dipyridamole (Persantin) inhibits the energy-linked reduction of NAD and oxidation of NADH with coenzyme Q 6 as acceptor catalyzed by submitochondrial particles. The aerobic oxidation of NADH or the anerobic oxidation catalyzed by fumarate were unaff
Publikováno v:
Journal of Biological Chemistry. 241:4771-4780
The ubiquinone reductase activity of a soluble extract of beef heart submitochondrial particles can be separated into two active fractions by chromatography on a hydroxylapatite column. Fraction I was further purified by ammonium sulfate fractionatio
Autor:
D.R. Sanadi, Richard L. Pharo
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects. 85:346-348
Publikováno v:
Biochimica et biophysica acta. 90