Zobrazeno 1 - 10
of 17
pro vyhledávání: '"L. Paul Sands"'
Autor:
Brittany Liebenow, Angela Jiang, Emily K. DiMarco, L. Paul Sands, Mary Moya-Mendez, Adrian W. Laxton, Mustafa S. Siddiqui, Ihtsham ul Haq, Kenneth T. Kishida
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Impulse Control Disorder (ICD) in Parkinson’s disease is a behavioral addiction induced by dopaminergic therapies, but otherwise unclear etiology. The current study investigates the interaction of reward processing variables, dopaminergic
Externí odkaz:
https://doaj.org/article/283fb407997245ceb2a70896a9a1a888
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 237 (2024)
Sex- and age-related differences in symptom prevalence and severity have been widely reported in patients with schizophrenia, yet the underlying mechanisms contributing to these differences are not well understood. N-methyl-D-aspartate (NMDA) recepto
Externí odkaz:
https://doaj.org/article/8d580c16c76248a9a7da302f4dbecf9c
Computational reinforcement learning, reward (and punishment), and dopamine in psychiatric disorders
Autor:
Brittany Liebenow, Rachel Jones, Emily DiMarco, Jonathan D. Trattner, Joseph Humphries, L. Paul Sands, Kasey P. Spry, Christina K. Johnson, Evelyn B. Farkas, Angela Jiang, Kenneth T. Kishida
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
In the DSM-5, psychiatric diagnoses are made based on self-reported symptoms and clinician-identified signs. Though helpful in choosing potential interventions based on the available regimens, this conceptualization of psychiatric diseases can limit
Externí odkaz:
https://doaj.org/article/ae18acc28f36488c8e1308bdf07ce8bf
Autor:
Kimberly M. Holter, Alex D. Lekander, Christina M. LaValley, Elizabeth G. Bedingham, Bethany E. Pierce, L. Paul Sands, Craig W. Lindsley, Carrie K. Jones, Robert W. Gould
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Selective negative allosteric modulators (NAMs) targeting the metabotropic glutamate receptor subtype 5 (mGlu5) demonstrate anxiolytic-like and antidepressant-like effects yet concern regarding adverse effect liability remains. Functional coupling of
Externí odkaz:
https://doaj.org/article/0a0ae44e0f6442668ba0e76ba53e03d1
Publikováno v:
Experimental and Clinical Psychopharmacology. 30:1-14
Females are uniquely sensitive to drugs of abuse at specific points in their reproductive cycle. Females' endogenous opioid system contributes to both reward-related processes and maternally relevant physiological functions, yet less is known about h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b72c5481a6e248a7848b2e28eee13a6e
https://doi.org/10.1037/pha0000427
https://doi.org/10.1037/pha0000427
Autor:
L. Paul Sands, Angela Jiang, Brittany Liebenow, Emily DiMarco, Adrian W. Laxton, Stephen B. Tatter, P. Read Montague, Kenneth T. Kishida
In the mammalian brain, midbrain dopamine neuron activity is hypothesized to encode reward prediction errors that promote learning and guide behavior by causing rapid changes in dopamine levels in target brain regions. This hypothesis (and alternativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6117ccfe6302bab54336eb3722948070
https://doi.org/10.1101/2023.02.24.529709
https://doi.org/10.1101/2023.02.24.529709
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173644 (2017)
Expanded polyglutamine repeats in different proteins are the known determinants of at least nine progressive neurodegenerative disorders whose symptoms include cognitive and motor impairment that worsen as patients age. One such disorder is Huntingto
Externí odkaz:
https://doaj.org/article/05a113113a294ca7923104d39982c885
Autor:
Rachel Jones, L. Paul Sands, Jonathan D. Trattner, Angela Jiang, Heather E. Douglas, Predrag V. Gligorovic, Kenneth Kishida
Publikováno v:
Biological Psychiatry. 91:S197-S198
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4726d3b36a575f6be5399978094684d5
https://doi.org/10.1016/j.biopsych.2022.02.508
https://doi.org/10.1016/j.biopsych.2022.02.508
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf282d94342e2bade47e859c052101a7
https://doi.org/10.1096/fasebj.2021.35.s1.03524
https://doi.org/10.1096/fasebj.2021.35.s1.03524
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bd57ebe0b4a4cf60c52f4653e9fc018
https://doi.org/10.1096/fasebj.2021.35.s1.03244
https://doi.org/10.1096/fasebj.2021.35.s1.03244