Zobrazeno 1 - 10
of 11
pro vyhledávání: '"L. Patrice McDaniel"'
Autor:
Vasily N. Dobrovolsky, L. Patrice McDaniel, M. Monserrat Pacheco-Martinez, Wei Ding, Mason G. Pearce
Publikováno v:
Food and Chemical Toxicology. 87:120-127
Acrylamide (ACR) and glycidyl methacrylate (GMA) are structurally related compounds used for making polymers with various properties. Both chemicals can be present in food either as a byproduct of processing or a constituent of packaging. We performe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964ed4d02de75c58ed6e72dec903fd7c
https://doi.org/10.1016/j.fct.2015.12.006
https://doi.org/10.1016/j.fct.2015.12.006
Autor:
Daniel R. Doerge, Eden Tareke, L. Patrice McDaniel, John F. Young, Nathan C. Twaddle, Mona I. Churchwell
Publikováno v:
Toxicology and Applied Pharmacology. 217:63-75
Acrylamide (AA) is a widely studied industrial chemical that is neurotoxic, mutagenic to somatic and germ cells and carcinogenic in rodents. AA is also formed in many commonly consumed starchy foods during cooking. Our previous toxicokinetic investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c37d67c7dc4ca9cf9299f735dbe3f4
https://doi.org/10.1016/j.taap.2006.07.013
https://doi.org/10.1016/j.taap.2006.07.013
Publikováno v:
Toxicology and Applied Pharmacology. 202:258-267
Acrylamide (AA) is a widely studied industrial chemical that is neurotoxic, mutagenic to somatic and germ cells, and carcinogenic in rodents. The recent discovery of AA at ppm levels in a wide variety of commonly consumed foods has energized research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c83b11adb7fdbdcb9df19a9baf4fd840
https://doi.org/10.1016/j.taap.2004.07.001
https://doi.org/10.1016/j.taap.2004.07.001
Autor:
Gonçalo Gamboa da Costa, Frederick A. Beland, Mona I. Churchwell, Nathan C. Twaddle, L. Patrice McDaniel, Daniel R. Doerge
Publikováno v:
Cancer Letters. 207:9-17
Acrylamide (AA) is a well-studied industrial toxicant; however, recent findings of AA at ppm levels in cooked starchy foods have refocused attention on the potential for neurotoxicity, germ cell mutagenicity, and carcinogenicity from AA. Oxidative me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75005fa9c73bd32ebcef0c61bccf997
https://doi.org/10.1016/j.canlet.2003.10.017
https://doi.org/10.1016/j.canlet.2003.10.017
Autor:
Christine B. Ambrosone, Fred F. Kadlubar, Szilárd Kostic, L. Patrice McDaniel, Bernadette Schoket, Shogo Ozawa, István Vincze, Yong Ming Tang
Publikováno v:
Carcinogenesis. 20:991-995
Carcinogen-DNA adducts may represent an intermediate end-point in the carcinogenic cascade and may reflect exposure to chemical carcinogens, as well as susceptibility and, ultimately, cancer risk. Interindividual variability in activity of enzymes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813161add5bc088babb760bbd44a0b90
https://doi.org/10.1093/carcin/20.6.991
https://doi.org/10.1093/carcin/20.6.991
Publikováno v:
Environmental and molecular mutagenesis. 53(5)
Aristolochic acid (AA) is a potent human nephrotoxin and carcinogen. We previously reported that AA treatment resulted in DNA damage and mutation in the kidney and liver of rats. In this study, we have determined the DNA adducts and mutations induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22db615ba0fdedab9a10e0b233029cfe
https://pubmed.ncbi.nlm.nih.gov/22508110
https://pubmed.ncbi.nlm.nih.gov/22508110
Autor:
Daniel R. Doerge, Vasily N. Dobrovolsky, Robert H. Heflich, Joseph G. Shaddock, Roberta A. Mittelstaedt, Wei Ding, L. Patrice McDaniel
Publikováno v:
Mutation research. 742(1-2)
Furan is a multispecies liver carcinogen whose cancer mode of action (MOA) is unclear. A major metabolite of furan is a direct acting mutagen; however, it is not known if genotoxicity is a key step in the tumors that result from exposure to furan. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377785e44fa1b2e80f7b0ec5bbab7ab2
https://pubmed.ncbi.nlm.nih.gov/22200623
https://pubmed.ncbi.nlm.nih.gov/22200623
Autor:
L. Patrice McDaniel, Timothy R. Fennell, Nathan C. Twaddle, Rodney W. Snyder, Daniel R. Doerge, Burhan I. Ghanayem, Mona I. Churchwell
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 88(2)
Acrylamide (AA) is an animal carcinogen, neurotoxin, and reproductive toxin. AA is formed in baked and fried carbohydrate-rich foods. Metabolism of AA occurs via epoxidation to glycidamide (GA) or direct conjugation with glutathione. Using CYP2E1-nul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf481b135aa014248bb7ac42cbd2288e
https://pubmed.ncbi.nlm.nih.gov/16141435
https://pubmed.ncbi.nlm.nih.gov/16141435
Publikováno v:
Toxicology and applied pharmacology. 208(3)
Acrylamide (AA) is a widely studied industrial chemical that is neurotoxic, mutagenic to somatic and germ cells, and carcinogenic in rodents. The recent discovery of AA at ppm levels in a wide variety of commonly consumed foods has energized research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::828dad2af915c8fe1392f0d37ee04b2c
https://pubmed.ncbi.nlm.nih.gov/16239164
https://pubmed.ncbi.nlm.nih.gov/16239164
Autor:
Daniel R. Doerge, Gonçalo Gamboa da Costa, Frederick A. Beland, Nathan C. Twaddle, Mona I. Churchwell, L. Patrice McDaniel
Publikováno v:
Mutation research. 580(1-2)
Acrylamide (AA) is an important industrial chemical that is neurotoxic, mutagenic to somatic and germ cells, and carcinogenic in chronic rodent bioassays. Recent findings of AA in many common starchy foods have sparked renewed interest in determining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d1e89b64f5daf27ade11678181f5de
https://pubmed.ncbi.nlm.nih.gov/15668115
https://pubmed.ncbi.nlm.nih.gov/15668115