Zobrazeno 1 - 10
of 21
pro vyhledávání: '"L. P. Pozdnyakova"'
Publikováno v:
Журнал инфектологии, Vol 15, Iss 3, Pp 15-28 (2023)
The literature review highlights modern ideas about the pathogenesis, pathomorphology, and clinical manifestations of central nervous system damage in patients with HIV infection, and also touches on the problems of diagnosis and treatment of these o
Externí odkaz:
https://doaj.org/article/96a5869405a941abb244d1f8ac0b212b
Autor:
O. G. Kurskaya, A. V. Anoshina, N. V. Leonova, O. A. Simkina, T. V. Komissarova, E. Yu. Esikova, L. L. Pozdnyakova, I. A. Sobolev, E. A. Prokopyeva, Т. A. Murashkina, E. A. Kazachkova, А. Yu. Alekseev, D. M. Danilenko, A. B. Komissarov, K. A. Stolyarov, A. V. Fadeev, A. A. Sominina, А. M. Shestopalov, K. A. Sharshov
Publikováno v:
Инфекция и иммунитет, Vol 11, Iss 4, Pp 723-736 (2021)
Influenza and other acute respiratory viral infections lead to a substantial incidence of severe cases and hospitalizations and so remain a global health problem. Within the frame of the Global Influenza Hospital Surveillance Network (GIHSN), we asse
Externí odkaz:
https://doaj.org/article/b519f8cfa0494e90b908374770564fb2
Publikováno v:
Журнал инфектологии, Vol 7, Iss 1, Pp 65-69 (2015)
The paper presents the analysis of clinical and laboratory symptoms in 35 adult patients with denger fever, Novosibirsk residents, which travelled in endemic countries, mostly Tailand. The classic form of the disease was determined in all cases. The
Externí odkaz:
https://doaj.org/article/4e4465d6039e406787f7a5eae678e0ec
Autor:
I. G. Dement’yeva, P. G. Sveshnikov, L. P. Pozdnyakova, Dmitry A. Dolgikh, T. K. Aliev, M. N. Bokov, V. A. Toporova, V. V. Argentova, Yu. A. Votchitseva, Mikhail P. Kirpichnikov, S.D. Varfolomeyev
Publikováno v:
Acta Naturae. 10:30-36
We obtained recombinant variants of human antibody FI6 broadly specific to hemagglutinins of the influenza A virus. On the basis of a bi-promoter (CMV, hEF1-HTLV) vector, we developed genetic constructs for the expression of the heavy and light chain
Autor:
I. G. Dementieva, Kirpichnikov Mp, D. A. Dolgikh, V. A. Toporova, O. B. Shchemchukova, A. A. Panina, D. S. Balabashin, M. N. Bokov, P. G. Sveshnikov, L. P. Pozdnyakova, T. K. Aliev
Publikováno v:
Acta Naturae
Currently, there are no approved therapies for targeted prevention and treatment of Ebola hemorrhagic fever. In the present work, we describe the development of a eukaryotic expression system for the production of three full-length chimeric antibodie
Autor:
A. A. Panina, P. G. Sveshnikov, I. G. Dement’yeva, V. A. Toporova, Mikhail P. Kirpichnikov, M. N. Bokov, D. A. Dolgikh, L. P. Pozdnyakova, T. K. Aliev, O. B. Shemchukova
Publikováno v:
Russian Journal of Bioorganic Chemistry. 43:409-420
Previously, we have determined the nucleotide and amino acid sequences of the variable domains of three mouse monoclonal antibodies specific to the individual epitopes of the Ebola virus glycoprotein: GPE118 (IgG), GPE325 (IgM) and GPE534 (IgG) [1].
Autor:
I. G. Dement’eva, V. A. Toporova, V. V. Argentova, Dmitry A. Dolgikh, M. N. Bokov, Mikhail P. Kirpichnikov, P. G. Sveshnikov, L. P. Pozdnyakova, T. K. Aliev
Publikováno v:
Doklady Biochemistry and Biophysics. 478:34-36
We obtained dimeric forms of IgA1- and IgA2m1-isotypes of FI6 antibody broadly specific to hemagglutinins of different subtypes of influenza A virus. It was shown that the dimers of IgA1 isotype are characterized by a higher antigen-binding activity
Autor:
D. A. Dolgikh, I. G. Dement’yeva, V. S. Rybchenko, M. N. Bokov, Mikhail P. Kirpichnikov, V. A. Toporova, P. G. Sveshnikov, L. P. Pozdnyakova, T. K. Aliev
Publikováno v:
Moscow University Biological Sciences Bulletin. 71:87-92
We studied the possibility of using a broadly neutralizing anti-influenza A antibody as a module for the development of different protein constructs for diagnostics. For this purpose, we constructed two recombinant proteins—a Fab-fragment of the an
Autor:
I. G. Dement’yeva, P. G. Sveshnikov, A. A. Panina, O. B. Schemchukova, D. A. Dolgikh, M. N. Bokov, L. P. Pozdnyakova, T. K. Aliev, Mikhail P. Kirpichnikov, N. E. Varlamov
Publikováno v:
Moscow University Biological Sciences Bulletin. 71:24-28
Balb/С mice were immunized with recombinant Ebola virus glycoprotein. Following the selection, screening, and cloning of murine hybridomas, we obtained five genetically stable clones of monoclonal antibodies GPE118 (IgG), GPE274 (IgM), GPE325 (IgM),
Autor:
T K, Aliev, I G, Dement'yeva, V A, Toporova, V V, Argentova, L P, Pozdnyakova, M N, Bokov, Yu A, Votchitseva, D A, Dolgikh, S D, Varfolomeyev, P G, Sveshnikov, M P, Kirpichnikov
Publikováno v:
Acta Naturae
We obtained recombinant variants of human antibody FI6 broadly specific to hemagglutinins of the influenza A virus. On the basis of a bi-promoter (CMV, hEF1-HTLV) vector, we developed genetic constructs for the expression of the heavy and light chain