Zobrazeno 1 - 10
of 69
pro vyhledávání: '"L. P. Osipova"'
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 26, Iss 2, Pp 188-195 (2022)
Investigation of the frequencies of functionally signif icant gene variants in the context of medical biology and gene geography is a relevant issue for studying the genetic structure of human populations. The transition from a traditional to an urba
Externí odkaz:
https://doaj.org/article/426f7866ccee45e7823750df09f5ff19
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 23, Iss 8, Pp 1011-1019 (2020)
Lipid metabolism disorders underlie the pathogenesis of a number of diseases. Indigenous peoples of Siberia have a specific genetically determined type of metabolism supporting such lipid blood parameters that favor increased consumption (in comparis
Externí odkaz:
https://doaj.org/article/07acdca164d64d44bddbedd7b940e976
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 22, Iss 2, Pp 205-211 (2018)
The study of the gene polymorphism of the system of biotransformation of xenobiotics is an important area of modern medical and genetic research. The aim of this work is to study the frequency of the alleles of the CYP1A1 (A2455G (*2C), rs1048943), C
Externí odkaz:
https://doaj.org/article/460607cff7f64e89aeb729cc7381a452
Autor:
R. P. Tiis, L. P. Osipova, T. V. Churkina, L. E. Tabikhanova, D. V. Lichman, E. N. Voronina, M. L. Filipenko
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 20, Iss 1, Pp 16-22 (2016)
The work concerns a polymorphism of the cytochrome Р450 CYP1A1 gene, the CYP1A1*2C variant (Ile462Val, rs1048943). This substitution results in a two- fold increase in enzyme activity, which leads to accumulation of active intermediates and increase
Externí odkaz:
https://doaj.org/article/c8d0af50ce8b4648a9deca81739289ce
Autor:
L. E. Tabikhanova, L. P. Osipova, T. V. Churkina, S. S. Kovalev, M. L. Filipenko, E. N. Voronina
Publikováno v:
Molecular Biology. 57:329-337
Autor:
L. V. Bezuglova, L. P. Osipova, E. I. Sergeeva, I. V. Deliy, L. E. Tabikhanova, S. V. Netesov, I. G. Netesova
Publikováno v:
Molecular Genetics, Microbiology and Virology. 37:146-152
Autor:
N. D. Vashakmadze, L. S. Namazova-Baranova, A. K. Gevorkyan, L. M. Kuzenkova, T. V. Podkletnova, M. A. Babaikina, A. V. Anikin, G. V. Kuznetsova, L. A. Osipova
Publikováno v:
Rossijskij Vestnik Perinatologii i Pediatrii, Vol 61, Iss 4, Pp 114-120 (2016)
Joint pathology without signs of inflammation must always arouse suspicion of lysosomal storage diseases, mucopolysaccharidosis (MPS) in particular. It is these orthopedic diseases in mild MPS type I, which are an early sign of the disease; moreover,
Externí odkaz:
https://doaj.org/article/51bdde6c02e5480789d1be7781f7167f
Autor:
Roza Pavlovna Tiis, Elena N. Voronina, L. P. Osipova, Daria Veniaminovna Lichman, Maxim L. Filipenko
Publikováno v:
BMC Genetics, Vol 21, Iss S1, Pp 1-7 (2020)
BMC Genetics
BMC Genetics
BackgroundN-acetyltransferase 2 plays a crucial role in the metabolism of a wide range of xenobiotics, including many drugs, carcinogens, and other chemicals in the human environment. The article presents for the first time data on the frequency of t
Autor:
Maxim L. Filipenko, Yuriy L. Orlov, L. P. Osipova, A.V. Melikhova, Elena N. Voronina, Elvira R. Galieva, D. V. Lichman, R. P. Tiis
Publikováno v:
Biomeditsinskaia khimiia. 67(3)
To search for new targets of therapy, it is necessary to reconstruct the gene network of the disease, and identify the interaction of genes, proteins, and drug compounds. Using the online bioinformatics tools we have analyzed the current data set rel
Autor:
A. V. Zubova, G. S. Russkikh, L. P. Osipova, L. M. Polyakov, N. G. Biushkina, O. N. Poteryaeva, T. V. Goltsova, T. V. Churkina, A. A. Rozumenko
Publikováno v:
Human Physiology. 43:700-704
We studied the concentrations of insulin, cortisol and glucose in blood serum of two groups of inhabitants of the Yamalo-Nenets Autonomous okrug (YaNAO) settlements (indigenous population and those who arrived from Central Russia). The insulin level