Zobrazeno 1 - 10 of 73 pro vyhledávání: '"L. O. Arthur"'
1
Inactivation of Human Immunodeficiency Virus Type 1 Infectivity with Preservation of Conformational and Functional Integrity of Virion Surface Proteins
Autor: Douglas K. Schneider, Kalachar Suryanarayana, Quentin J. Sattentau, Mark T. Esser, Jeffrey L. Rossio, Louis E. Henderson, Elena Chertova, J. D. Lifson, Jr Jw Bess, MK Grimes, Theresa A. Wiltrout, Gabriela M. Vasquez, L O Arthur
Publikováno v: Journal of Virology. 72:7992-8001
Whole inactivated viral particles have been successfully used as vaccines for some viruses, but procedures historically used for inactivation can denature virion proteins. Results have been inconsistent, with enhancement of disease rather than protec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90efad9e789c68a09a57ad3e17db6a42
https://doi.org/10.1128/jvi.72.10.7992-8001.1998
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2
Cytoskeletal proteins inside human immunodeficiency virus type 1 virions
Autor: Bradley P. Kane, Laura K. Busch, L O Arthur, Raymond Sowder, Louis E. Henderson, Elena Chertova, Lori V. Coren, David E. Ott, Donald G. Johnson
Publikováno v: Journal of Virology. 70:7734-7743
We have identified three types of cytoskeletal proteins inside human immunodeficiency virus type 1 (HIV-1) virions by analyzing subtilisin-digested particles. HIV-1 virions were digested with protease, and the treated particles were isolated by sucro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7aa894b88ba468c9c13f5dac877e1fc
https://doi.org/10.1128/jvi.70.11.7734-7743.1996
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3
Isolation and characterization of a syncytium-inducing, macrophage/T-cell line-tropic human immunodeficiency virus type 1 isolate that readily infects chimpanzee cells in vitro and in vivo
Autor: George Englund, Z Israel, Riri Shibata, Alan M. Schultz, H C Lane, C Broscius, Theodore S. Theodore, Alicia Buckler-White, L O Arthur, M D Hoggan
Publikováno v: Journal of Virology. 69:4453-4462
Fresh human immunodeficiency virus type 1 (HIV-1) isolates from patients with AIDS were screened for infectivity in chimpanzee peripheral blood mononuclear cells (PBMC) to identify strains potentially able to generate high virus loads in an inoculate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f34a603fd69027a57d8580204e6dfb
https://doi.org/10.1128/jvi.69.7.4453-4462.1995
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4
Macaques immunized with HLA-DR are protected from challenge with simian immunodeficiency virus
Autor: Jack L. Strominger, DL Mann, RG Urban, Jr Jw Bess, William R. Morton, Louis E. Henderson, Raoul E. Benveniste, L O Arthur
Publikováno v: Journal of Virology. 69:3117-3124
Macaques immunized with uninfected human cells have been shown to be protected from challenge with simian immunodeficiency virus (SIV) propagated in human cells. To identify the potential antigens involved in this protection, macaques were immunized
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6cb356837c3f7c4d85dc9b32e20098
https://doi.org/10.1128/jvi.69.5.3117-3124.1995
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5
The majority of cells are superinfected in a cloned cell line that produces high levels of human immunodeficiency virus type 1 strain MN
Autor: L O Arthur, S M Nigida, David E. Ott, Louis E. Henderson
Publikováno v: Journal of Virology. 69:2443-2450
We have isolated seven single-cell clones from an H9 culture infected with human immunodeficiency virus type 1 strain MN so that a stable producer of virus could be obtained. DNAs from these clones were examined by Southern blot analysis and found to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbd738d0de19aa23e1f47b72f8dfca3
https://doi.org/10.1128/jvi.69.4.2443-2450.1995
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6
The two zinc fingers in the human immunodeficiency virus type 1 nucleocapsid protein are not functionally equivalent
Autor: Louis E. Henderson, Robert J. Gorelick, L O Arthur, D J Chabot, Alan Rein
Publikováno v: Journal of Virology. 67:4027-4036
The highly conserved zinc fingers in retroviral nucleocapsid (NC) proteins have the general structure Cys-(X)2-Cys-(X)4-His-(X)4-Cys. Human immunodeficiency virus type 1 (HIV-1) contains two Zn2+ fingers, and mutants were constructed in which the nat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5175b8de6e0e48fd0135383476615c3
https://doi.org/10.1128/jvi.67.7.4027-4036.1993
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7
Potent stimulation of monocytic endothelin-1 production by HIV-1 glycoprotein 120
Autor: H Ehrenreich, P Rieckmann, F Sinowatz, K A Weih, L O Arthur, F D Goebel, P R Burd, J E Coligan, K A Clouse
Publikováno v: The Journal of Immunology. 150:4601-4609
Monocytes/macrophages play a critical role in the pathogenesis of HIV infection, both as targets for virus replication and as sources of production of multifunctional cytokines. Endothelins, peptides with potent vasoconstricting activities originally
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e2485df6965ece480077c063a4ab3f9f
https://doi.org/10.4049/jimmunol.150.10.4601
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8
Conversion of an immunogenic human immunodeficiency virus (HIV) envelope synthetic peptide to a tolerogen in chimpanzees by the fusogenic domain of HIV gp41 envelope protein
Autor: L O Arthur, P Frost, Mary Kate Hart, Thomas J. Palker, T J Matthews, Barton F. Haynes, Richard M. Scearce, Charlene McDanal, A. J. Langlois, D M Jones
Publikováno v: The Journal of Experimental Medicine
The fusogenic (F) domain of human immunodeficiency virus (HIV) gp41 envelope (env) protein has sequence similarities to many virus and mediates the fusion of HIV-infected cells. During a survey of the immunogenicity of HIV env peptides in chimpanzees
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df7a7902a4f93786913f05e279d2015
https://doi.org/10.1084/jem.177.3.717
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9
Tightly bound zinc in human immunodeficiency virus type 1, human T-cell leukemia virus type I, and other retroviruses
Autor: LJ Schumack, HJ Issaq, MK Grimes, Louis E. Henderson, L O Arthur, Jr Jw Bess, PJ Powell
Publikováno v: Journal of Virology. 66:840-847
Human immunodeficiency virus type 1 (HIV-1) and human T-cell leukemia virus type I (HTLV-I) were purified by sucrose density gradient centrifugation in the presence of 1 mM EDTA. Pelleted gradient fractions were analyzed for total protein, total Gag
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a113449875123092fa79ea097f03651
https://doi.org/10.1128/jvi.66.2.840-847.1992
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10
Whole inactivated SIV virion vaccines with functional envelope glycoproteins: safety, immunogenicity, and activity against intrarectal challenge
Autor: J D, Lifson, M, Piatak, J L, Rossio, J, Bess, E, Chertova, D, Schneider, R, Kiser, V, Coalter, B, Poore, R, Imming, R C, Desrosiers, L E, Henderson, L O, Arthur
Publikováno v: Journal of medical primatology. 31(4-5)
A novel type of whole inactivated simian immunodeficiency virus (SIV) virion vaccine immunogen with functional envelope glycoproteins was evaluated, without adjuvant, in rhesus macaques. Immunogens included purified inactivated virions of SIVmac239,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::955dbb0be0d5f205ff76a08c299a5872
https://pubmed.ncbi.nlm.nih.gov/12390543
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