Zobrazeno 1 - 10
of 16
pro vyhledávání: '"L. N. Sansom"'
Publikováno v:
Pharmacoepidemiology and drug safety. 8(4)
National medicinal drug policies are employed around the world as a means of maximizing the benefits of medication use. An essential component to the implementation of these policies is their concurrent evaluation, which informs future policy impleme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8f07d284bdfcf85759d6c8ede37b6cc8
https://pubmed.ncbi.nlm.nih.gov/15073922
https://pubmed.ncbi.nlm.nih.gov/15073922
Autor:
D. Rowett, K. Latimer, L. N. Sansom, R. E. Ruffin, F. May, G. Henderson, P. J. Hayball, Received: February 1995/Accepted May
The influence of hypoxaemia on the disposition of two common drugs has been examined in ten adults with stable chronic respiratory failure.There were two experimental periods in this cross-over study: during these periods supplemental oxygen was eith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd3be7fde0314f1e9f33283ab845b39
https://hdl.handle.net/1959.8/41089
https://hdl.handle.net/1959.8/41089
Autor:
John O. Miners, C. J. Doecke, S. M. Pond, Maurice E. Veronese, Donald J. Birkett, L. N. Sansom, Michael E. McManus
1. The metabolic interaction of phenytoin and tolbutamide in human liver microsomes was investigated. 2. Phenytoin 4-hydroxylation (mean Km 29.6 microM, n = 3) was competitively inhibited by tolbutamide (mean Ki 106.2 microM, n = 3) and tolbutamide m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b080942147c1fd50273338bbd910a9
https://europepmc.org/articles/PMC1368377/
https://europepmc.org/articles/PMC1368377/
Publikováno v:
European journal of clinical pharmacology. 38(2)
Thirteen male patients were administered 20 mg of temazepam orally 1 to 2 h prior to undergoing spinal anaesthesia for a urological procedure. Samples of blood and CSF were drawn just before insertion of the spinal and the concentration of drug estim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6436835b3946da217627d70f5c25b43c
https://pubmed.ncbi.nlm.nih.gov/1970959
https://pubmed.ncbi.nlm.nih.gov/1970959
Publikováno v:
Antimicrobial Agents and Chemotherapy. 28:293-298
Moxalactam kinetics during continuous ambulatory peritoneal dialysis (CAPD) was followed in eight patients after a single intraperitoneal dose of 1 g. Approximately 60% of the dose was absorbed after a dwell time of 4 h. Dialysis solutions were excha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915d961644842ef0e6b452972a04d692
https://doi.org/10.1128/aac.28.2.293
https://doi.org/10.1128/aac.28.2.293
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 21:527-530
The inadequacy of single, simple arithmetic corrections for salicylate interference in the widely employed Glynn and Kendal technique for plasma paracetamol assay is highlighted by reference to an actual case of combined salicylate/paracetamol intoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2bb2e8c1ec60e78e1ea9609a8cbe1af
https://doi.org/10.1177/000456328402100617
https://doi.org/10.1177/000456328402100617
Publikováno v:
Medical Journal of Australia. 2:590-592
In children, the blood level of phenytoin was found to be significantly higher when 100 mg capsules rather than 100 mg tablets were administered. When, on the other hand, 30 mg capsules and tablets were compared; the situation was reversed; tablets p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5931b9948b15ff59f740e14cae40d255
https://doi.org/10.5694/j.1326-5377.1975.tb106113.x
https://doi.org/10.5694/j.1326-5377.1975.tb106113.x
Publikováno v:
European Journal of Clinical Pharmacology. 35:437-439
The pharmacokinetics of a new 10 mg sublingual tablet formulation of temazepam and those of a currently marketed 10 mg oral capsule formulation were evaluated in a group of ten healthy volunteers. No significant differences were observed between the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d96b47efb2deef2889eeb6849f09e37a
https://doi.org/10.1007/bf00561380
https://doi.org/10.1007/bf00561380
Publikováno v:
Pharmaceutica acta Helvetiae. 51(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::afb14a9758f6e93959e6d2361f17b14f
https://pubmed.ncbi.nlm.nih.gov/821062
https://pubmed.ncbi.nlm.nih.gov/821062
Publikováno v:
The Medical journal of Australia. 2(4)
Displacement of phenytoin from plasma proteins by valproate causes a reduction in total serum phenytoin levels. However, no adjustment of phenytoin dosage is warranted, unless clinically indicated, since the free phenytoin levels remain unchanged.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::066b589b4f5439e56f42104b4dd2f9f6
https://pubmed.ncbi.nlm.nih.gov/6776391
https://pubmed.ncbi.nlm.nih.gov/6776391