Zobrazeno 1 - 10
of 86
pro vyhledávání: '"L. N. Harris"'
Autor:
A. S. Mansfield, Z. Wei, R. Mehra, A. T. Shaw, C. H. Lieu, P. M. Forde, A. E. Drilon, E. P. Mitchell, J. J. Wright, N. Takebe, E. Sharon, D. Hovelson, S. Tomlins, J. Zeng, K. Poorman, N. Malik, R. J. Gray, S. Li, L. M. McShane, L. V. Rubinstein, D. Patton, P. M. Williams, S. R. Hamilton, B. A. Conley, C. L. Arteaga, L. N. Harris, P. J. O’Dwyer, A. P. Chen, K. T. Flaherty
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-6 (2022)
Abstract The NCI-MATCH was designed to characterize the efficacy of targeted therapies in histology-agnostic driver mutation-positive malignancies. Sub-protocols F and G were developed to evaluate the role of crizotinib in rare tumors that harbored e
Externí odkaz:
https://doaj.org/article/3cae99beef0c4a4abe8621283988fc92
Publikováno v:
Journal of fish biology. 84(1)
Three populations of Arctic charr Salvelinus alpinus from southern Baffin Island were previously identified to display variable migratory phenotypes, with an anadromous component of the population and another remaining resident in fresh water. In thi
Publikováno v:
American Journal of Enology and Viticulture. 42:109-112
Publikováno v:
American Journal of Enology and Viticulture. 42:103-108
Publikováno v:
Clinical genetics. 69(5)
Although social and ethical issues related to the storage and use of biologic specimens for genetic research have been discussed extensively in the medical literature, few empiric data exist describing patients' views. This qualitative study explored
Autor:
C L, Vogel, M A, Cobleigh, D, Tripathy, J C, Gutheil, L N, Harris, L, Fehrenbacher, D J, Slamon, M, Murphy, W F, Novotny, M, Burchmore, S, Shak, S J, Stewart
Publikováno v:
Oncology. 61
The pivotal phase II and III Herceptin trials proved the efficacy and safety of second- or third-line single-agent Herceptin and first-line Herceptin in combination with chemotherapy, respectively. In the current trial, 114 patients were randomized t
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(6)
ErbB2 (HER-2) gene amplification and overexpression have been shown to predict a better outcome with doxorubicin-based chemotherapy as opposed to alkylator-based chemotherapy in early stage breast cancer. To understand the mechanism of differential r
Autor:
C, Vogel, M A., Cobleigh, D, Tripathy, J C., Gutheil, L N., Harris, L, Fehrenbacher, D J., Slamon, M, Murphy, W F., Novotny, M, Burchmore, S, Shak, S J., Stewart
Publikováno v:
European journal of cancer (Oxford, England : 1990). 37
Following confirmation of the appropriate dosage, safety and potential efficacy of Herceptin(R) (trastuzumab) in small-scale phase I and II trials involving patients with refractory disease, a large trial was conducted in 222 patients with breast can
Autor:
C, Vogel, M A, Cobleigh, D, Tripathy, J C, Gutheil, L N, Harris, L, Fehrenbacher, D J, Slamon, M, Murphy, W F, Novotny, M, Burchmore, S, Shak, S J, Stewart
Publikováno v:
European journal of cancer (Oxford, England : 1990). 37
Following confirmation of the appropriate dosage, safety and potential efficacy of Herceptin(trastuzumab) in small-scale phase I and II trials involving patients with refractory disease, a large trial was conducted in 222 patients with breast cancer
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(4)
HER2 (erbB-2) proto-oncogene amplification and/or overexpression correlate with poor prognosis in many malignancies. The precise biological role of this oncogenic signaling pathway (which also involves the HER4 gene) in breast cancer is unclear. One