Zobrazeno 1 - 10
of 135
pro vyhledávání: '"L. Moye"'
Autor:
Joselyn S. Soto, Yasaman Jami-Alahmadi, Jakelyn Chacon, Stefanie L. Moye, Blanca Diaz-Castro, James A. Wohlschlegel, Baljit S. Khakh
Publikováno v:
Nature. 616:764-773
Astrocytes and neurons extensively interact in the brain. Identifying astrocyte and neuron proteomes is essential for elucidating the protein networks that dictate their respective contributions to physiology and disease. Here we used cell-specific a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2de17a2dfbdad3f93dadeab3732637c1
https://doi.org/10.1038/s41586-023-05927-7
https://doi.org/10.1038/s41586-023-05927-7
Cancer-associated noncoding mutations affect RNA G-quadruplex-mediated regulation of gene expression
Autor:
Mahdi Zeraati, Aaron L. Moye, Jason W. H. Wong, Dilmi Perera, Mark J. Cowley, Daniel U. Christ, Tracy M. Bryan, Marcel E. Dinger
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Cancer is a multifactorial disease driven by a combination of genetic and environmental factors. Many cancer driver mutations have been characterised in protein-coding regions of the genome. However, mutations in noncoding regions associated
Externí odkaz:
https://doaj.org/article/59ab4a1d4af84fbd87536aa985af8b63
Autor:
Sungmin Yang, Kyungsik Ha, Woojeung Song, Masashi Fujita, Kirsten Kübler, Paz Polak, Carolina Garcia de Alba Rivas, Patrizia Pessina, Julio Sainz de Aja, Samuel Rowbotham, Preetida Bhetariya, Antonella Dost, Aaron L. Moye, Eiso Hiyama, Hidewaki Nakagawa, Carla F. Kim, Hong-Gee Kim, Hwajin Lee
We here present COOBoostR (https://github.com/SWJ9385/COOBoostR), a computational method designed for the putative prediction of tissue-or cell-of-origin of various cancer types. COOBoostR leverages regional somatic mutation density information and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f37cd5a7432f8ae9a82c6b1a86c27819
https://doi.org/10.1101/2022.10.24.513446
https://doi.org/10.1101/2022.10.24.513446
Autor:
Bin Zhu, Rachel Lokanga, Natalie Saini, Francisco Martínez-Jiménez, Jung Kim, Kevin M. Brown, Laura Mendoza, Kerstin Heselmeyer-Haddad, Andrea Castro, Mengying Li, Amy Hutchinson, Burcak Otlu, Aaron L Moye, Lucia Anna Muscarella, Nathan Cole, Michael Kebede, Neil E. Caporaso, Scott M. Lawrence, Paul Hofman, Dario Consonni, Manuela Costantini, Naser Ansari-Pour, Hannah Carter, Jonas S Almeida, Yohan Bossé, Maria Luana Poeta, Jian Sang, Bonnie E. Gould Rothberg, Mary E. Olanich, Maria Teresa Landi, Philippe Joubert, Jennifer Rosenbaum, Azhar Khandekar, Thomas Ried, Angela Cecilia Pesatori, Qing Lan, Carla F. Kim, Jiyeon Choi, Douglas R. Stewart, Samuel H. Wilson, Dmitry A. Gordenin, Abel Gonzalez-Perez, Tongwu Zhang, Petra Lenz, Montserrat Garcia-Closas, Nuria Lopez-Bigas, David C. Wedge, Daniela Hirsch, Praphulla M S Bhawsar, Matthew B. Schabath, Yves Pommier, Jianxin Shi, Nathaniel Rothman, Ludmil B. Alexandrov, Máire A. Duggan, S M Ashiqul Islam, Iliana Peneva, Stephen J. Chanock, Wei Zhao, Phuc H Hoang, Leszek J. Klimczak
Publikováno v:
Nat Genet
Lung cancer in never smokers (LCINS) is a common cause of cancer mortality but its genomic landscape is poorly characterized. Here high-coverage whole-genome sequencing of 232 LCINS showed 3 subtypes defined by copy number aberrations. The dominant s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f4ca097cf70b23aa95ba7142ac352f
https://doi.org/10.1038/s41588-021-00920-0
https://doi.org/10.1038/s41588-021-00920-0
Akademický článek
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Publikováno v:
Oncogene
Neurofibromatosis type 1 (NF1) is an autosomal dominant genetic disease and one of the most common inherited tumor predisposition syndromes, affecting 1 in 3000 individuals worldwide. The NF1 gene encodes neurofibromin, a large protein with RAS GTP-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad3c4d56ae5b996be654f874a0f4474f
https://pubmed.ncbi.nlm.nih.gov/35066574
https://pubmed.ncbi.nlm.nih.gov/35066574
Publikováno v:
J Neurosci
Astrocytes exist throughout the CNS and affect neural circuits and behavior through intracellular Ca(2+) signaling. Studying the function(s) of astrocyte Ca(2+) signaling has proven difficult because of the paucity of tools to achieve selective atten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::46a54e443e31124bd68f717f0f978281
https://pubmed.ncbi.nlm.nih.gov/33903221
https://pubmed.ncbi.nlm.nih.gov/33903221
Autor:
Sharon M. Louie, Aaron L. Moye, Irene G. Wong, Emery Lu, Andrea Shehaj, Carolina Garcia-de-Alba, Erhan Ararat, Benjamin A. Raby, Bao Lu, Margherita Paschini, Roderick T. Bronson, Carla F. Kim
Publikováno v:
Cell Reports. 39:110662
Lung progenitor cells are crucial for regeneration following injury, yet it is unclear whether lung progenitor cells can be functionally engrafted after transplantation. We transplanted organoid cells derived from alveolar type II (AT2) cells enriche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eebf00b0681ff8107da61d1c9153b937
https://doi.org/10.1016/j.celrep.2022.110662
https://doi.org/10.1016/j.celrep.2022.110662
Autor:
Roberto, F. M., Ochoa, M.L. F., Haro, L. Moye, Paul, A. G., Jose Manuel, A. R., Flores Rendon, A. R.
Publikováno v:
Endoscopy; 2024 Supplement 2, Vol. 56, pS447-S448, 2p
Autor:
Carla F. Kim, Ryan M. Hekman, Benjamin C. Blum, William D. Wallace, Eileen Fung, Steven M. Dubinett, Roderick T. Bronson, Preetida J. Bhetariya, Sharon M. Louie, Carlos Villacorta-Martin, Antonella F.M. Dost, Andrew Emili, Jane Yanagawa, Julio Sainz de Aja, Dar Heinze, Marall Vedaie, Gustavo Mostoslavsky, Gregory A. Fishbein, Mary E. Piper, Julian H. Kwan, Samuel P. Rowbotham, Linh M. Tran, Kostyantyn Krysan, Jessie Huang, Aaron L. Moye, Darrell N. Kotton
Publikováno v:
Cell stem cell, vol 27, iss 4
Cell Stem Cell
Cell Stem Cell
Summary Mutant KRAS is a common driver in epithelial cancers. Nevertheless, molecular changes occurring early after activation of oncogenic KRAS in epithelial cells remain poorly understood. We compared transcriptional changes at single-cell resoluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc7ee7e1f223f34dcae0593d2b9c2b20
https://escholarship.org/uc/item/59d4j07r
https://escholarship.org/uc/item/59d4j07r